H2A0M7 (PLSP_PINMG) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Peroxidase-like protein
Organism	Pinctada margaritifera (Black-lipped pearl oyster)
Taxonomic identifier	102329 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Lophotrochozoa › Mollusca › Bivalvia › Pteriomorphia › Pterioida › Pterioidea › Pteriidae › Pinctada

Protein attributes

Sequence length	793 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Secreted Ref.2.
Tissue specificity	Prismatic layer of shell (at protein level). Ref.2
Sequence similarities	Belongs to the peroxidase family.

Ontologies

Keywords
Cellular component	Secreted
Domain	Signal
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological_process	response to oxidative stress Inferred from electronic annotation. Source: InterPro
Cellular_component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	heme binding Inferred from electronic annotation. Source: InterPro peroxidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 20	20	Potential
	Chain	21 – 793	773	Peroxidase-like protein		PRO_0000418021

Sequences

	Sequence		Length	Mass (Da)
	H2A0M7 [UniParc]. Last modified March 21, 2012. Version 1. Checksum: DD91EEE3CD70A1E4	FASTA	793	88,310
	10 20 30 40 50 60 MNLFICHVFL LLLHGYLIIC QDIPPDTIIS AVNTAQQEVT QREASSFSQQ QARASVAAFA 70 80 90 100 110 120 GAPQPAAVLA ASRPARTGLD RFNRRNDPQR NTELSIGGQV TQRATLALRS SDPASAAAPA 130 140 150 160 170 180 ARTLTPLDAR APAAGFSASS TMTFRNAAAQ SCTDSRPVTV CDPQQRYRET DGQCNNLVFP 190 200 210 220 230 240 SFPSGAFKLG AAFTAQGRFL FPAYDDGVSS PRIRSVIPGF LLPNARLVSR NVHSGTAFDS 250 260 270 280 290 300 DRHTPFLTHF GQFIDHDIVS TPETEPKFTM PNSHCCLEPN LEECFNINFE PDPLLQGSCI 310 320 330 340 350 360 RFNRADTAPS YFCNPGPRLQ QNQRSSFVDG TMVYGWDVEQ ENRLREPGTG RLISEGDDQL 370 380 390 400 410 420 KLEPVADPLN PPCFPVDNRC FEAGDHRSLE TVPLTVMHIM FLRRHNLIVQ ELQNLPLPWT 430 440 450 460 470 480 PELLFQEAKR IVVAELQHIT YNEFLPRVLG PQFMTIFRLW PAPLFSDTYS PLVDPRTTSG 490 500 510 520 530 540 FSVAAYRFGH SLVRNVHDQI GPGGLPVNNL LLQDHFDRLQ THLNVFPGGN TEGFARWMKL 550 560 570 580 590 600 SQKSRADRTL VDGLQNNLFP CEDPDCPMGG GVTKSFDLAA LNIQRGRDHG LPPYTAWRYW 610 620 630 640 650 660 CTGRRAFVFT PNAVGLSDHS PFEANILSNT YRHVDDIDLF TGGMTEMRRP GALLGPTLSC 670 680 690 700 710 720 IIGLQFSNYK RGDRFFYERP DPVMAFTPGQ LQAIKETSLA KILCSTMRSF SNVQIBAMDR 730 740 750 760 770 780 VSPSNPIVNC DELRSQDIIA KIPFLWNQLP NRAIQSAAAR ASNISGRTGL RVSTRFEDPA 790 MLRLIGRRRL YKH

References

[1]	"Transcriptome and proteome analysis of Pinctada margaritifera calcifying mantle and shell: focus on biomineralization." Joubert C., Piquemal D., Marie B., Manchon L., Pierrat F., Zanella-Cleon I., Cochennec-Laureau N., Gueguen Y., Montagnani C. BMC Genomics 11:613-613(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], IDENTIFICATION. Tissue: Mantle.
[2]	"Dissimilar protein secretions control the deposition of nacreous and prismatic shell layers by the pearl oyster mantle epithelia." Marie B., Zanella-cleon I., Jackson D., Marin F. Submitted (OCT-2011) to UniProtKB Cited for: PROTEIN SEQUENCE OF 431-447 AND 633-648, SUBCELLULAR LOCATION, TISSUE SPECIFICITY. Tissue: Shell.

Cross-references

Sequence databases
EMBL GenBank DDBJ	HE610394 mRNA. Translation: CCE46168.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	1.10.640.10. 2 hits.
InterPro	IPR010255. Haem_peroxidase. IPR002007. Haem_peroxidase_animal. IPR019791. Haem_peroxidase_animal_subgr. [Graphical view]
Pfam	PF03098. An_peroxidase. 1 hit. [Graphical view]
PRINTS	PR00457. ANPEROXIDASE.
SUPFAM	SSF48113. Peroxidase_super. 1 hit.
PROSITE	PS00435. PEROXIDASE_1. False negative. PS00436. PEROXIDASE_2. False negative. PS50292. PEROXIDASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PLSP_PINMG

Accession

Primary (citable) accession number: H2A0M7

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 13, 2012
Last sequence update:	March 21, 2012
Last modified:	March 6, 2013
This is version 8 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)