Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

H2A0L6

- HEX_PINMG

UniProt

H2A0L6 - HEX_PINMG

Protein

Putative beta-hexosaminidase

Gene
N/A
Organism
Pinctada margaritifera (Black-lipped pearl oyster)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 14 (01 Oct 2014)
      Sequence version 1 (21 Mar 2012)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.By similarity

    Pathwayi

    GO - Molecular functioni

    1. beta-N-acetylhexosaminidase activity Source: UniProtKB-EC
    2. polysaccharide binding Source: InterPro

    GO - Biological processi

    1. carbohydrate metabolic process Source: InterPro
    2. chitin catabolic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Hydrolase

    Enzyme and pathway databases

    UniPathwayiUPA00349.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative beta-hexosaminidaseBy similarity (EC:3.2.1.52By similarity)
    Alternative name(s):
    Beta-N-acetylhexosaminidaseBy similarity
    ChitobiaseBy similarity
    N-acetyl-beta-glucosaminidaseBy similarity
    OrganismiPinctada margaritifera (Black-lipped pearl oyster)
    Taxonomic identifieri102329 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaBivalviaPteriomorphiaPterioidaPterioideaPteriidaePinctada

    Subcellular locationi

    Secreted 1 Publication

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2323Sequence AnalysisAdd
    BLAST
    Chaini24 – 11351112Putative beta-hexosaminidaseSequence AnalysisPRO_0000418019Add
    BLAST

    Expressioni

    Tissue specificityi

    Prismatic layer of shell (at protein level). Expressed primarily in the mantle with highest level in the mantle edge and lower level in the mantle pallium.1 Publication

    Family & Domainsi

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi937 – 100468Pro-richSequence AnalysisAdd
    BLAST
    Compositional biasi1006 – 1133128Gln-richSequence AnalysisAdd
    BLAST

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 20 family.Sequence Analysis

    Keywords - Domaini

    Signal

    Family and domain databases

    Gene3Di2.60.40.290. 1 hit.
    3.20.20.80. 1 hit.
    3.30.379.10. 1 hit.
    InterProiIPR025705. Beta_hexosaminidase_sua/sub.
    IPR008965. Carb-bd_dom.
    IPR012291. CBD_carb-bd_dom.
    IPR004866. CHB/HEX_N_dom.
    IPR029018. Chitobiase/Hex_dom_2-like.
    IPR015883. Glyco_hydro_20_cat-core.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view]
    PfamiPF03173. CHB_HEX. 1 hit.
    PF00728. Glyco_hydro_20. 1 hit.
    [Graphical view]
    PRINTSiPR00738. GLHYDRLASE20.
    SUPFAMiSSF49384. SSF49384. 1 hit.
    SSF51445. SSF51445. 2 hits.
    SSF55545. SSF55545. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    H2A0L6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKWVKSGVGI LGILLTICHA VTSQGHILDI TDSLKITFKT LSNFGPRAQS     50
    IQNVTIENVG IKDIPDSGWR CYFCHDQLLF PGTFNLARNQ YFLRPILDNY 100
    VVLSDGFLLE FIKGCMYRIT PIPRNAPIKT RDKREFTLLA EQFSVSKYDS 150
    FPKWYCETIS GGNTEVGIIR NTENLKYVED FDSSYNWFRI PHDFRSVPLQ 200
    PQDRFSANHK ASSVDECKYK VIPTPVKASV SKVQRNFGTT VYYGTTDTSI 250
    RGREKLFKVA EQLALKHNLG LVEITPGLTV NNGISLVVTG NYVERNIPSP 300
    DEAYSLTVTA DLISIEAPAL PGLINGIETI HSLSAWDMAL PYGGIKDFPR 350
    FPFRGIFLDI ASNFPGYNYI KKFLTVMAQY KLNKLVLPMY NNEGFRLQLN 400
    DSPRYEFQAL HMIGGKRCHD LKEEKCLFSQ LGSGPDSSGG YLTKAQMTDL 450
    IKTADLLNIE IIMSMNIGES ARGAIVPLKQ SPHSRLLYDP DDTDFVDRFY 500
    PQKDTSMNPC REETTYFYDH MLKQLKDIYN AASVPLKTIM IGSKVNFDQV 550
    LNSKYCYASN LNSTQRLMAR GNLERNINGF KLNFTKRLVK TAHDNGIKEV 600
    MAIDDVFTTE FDAEGNTPNT VYDTKNSDNS TRFNATVTAV HSRYDTVRDE 650
    RLWKRGDRFA ELGYKVILSP PILDFNYAVE PDPDRPGDYD SVIRNISFSK 700
    LFRFVPDSRC CNIPNAIQHD CALESDCTTA GAKDSYIGTL GKLDTRKLRS 750
    LKDWNELLFP RLLIFAERSW HKSSWEDSFG PHRASVNNIT RQLITNYTVP 800
    NWNDINNEES KVLGCISRKE KLRLMHEDGL KPYVEPPGAR LLGGNTMRIA 850
    ASTTEDSFWV QASVNGNPWT DNVKILDVNP TDSVRLRTVH PAKAELRSKE 900
    VKLNLTSLPT PRERFRKIAQ DALSRRIGID IQRARMPPMP VNPAYRPPVP 950
    LPSFDPADDR APDLAAIAAA HPPPLPPGMP SHMMPNMPPP FPPRPPFGPP 1000
    MLPPGQMRAL GQQAGQALRG QGTALGPQTG QQPMPAQPRG PLTGQAAGTG 1050
    VAGQTGQQPS TAGQGTQQGL PGQQRGGVLP GQWPFFPGMP AAQFPPMFNP 1100
    QMQRALQMRG QGQIPQRTQG AAAGAGQSRI PQQAG 1135
    Length:1,135
    Mass (Da):126,661
    Last modified:March 21, 2012 - v1
    Checksum:i208E25A2E93AA61E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HE610383 mRNA. Translation: CCE46157.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HE610383 mRNA. Translation: CCE46157.1 .

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00349 .

    Family and domain databases

    Gene3Di 2.60.40.290. 1 hit.
    3.20.20.80. 1 hit.
    3.30.379.10. 1 hit.
    InterProi IPR025705. Beta_hexosaminidase_sua/sub.
    IPR008965. Carb-bd_dom.
    IPR012291. CBD_carb-bd_dom.
    IPR004866. CHB/HEX_N_dom.
    IPR029018. Chitobiase/Hex_dom_2-like.
    IPR015883. Glyco_hydro_20_cat-core.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view ]
    Pfami PF03173. CHB_HEX. 1 hit.
    PF00728. Glyco_hydro_20. 1 hit.
    [Graphical view ]
    PRINTSi PR00738. GLHYDRLASE20.
    SUPFAMi SSF49384. SSF49384. 1 hit.
    SSF51445. SSF51445. 2 hits.
    SSF55545. SSF55545. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Transcriptome and proteome analysis of Pinctada margaritifera calcifying mantle and shell: focus on biomineralization."
      Joubert C., Piquemal D., Marie B., Manchon L., Pierrat F., Zanella-Cleon I., Cochennec-Laureau N., Gueguen Y., Montagnani C.
      BMC Genomics 11:613-613(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], IDENTIFICATION.
      Tissue: Mantle.
    2. "Different secretory repertoires control the biomineralization processes of prism and nacre deposition of the pearl oyster shell."
      Marie B., Joubert C., Tayale A., Zanella-Cleon I., Belliard C., Piquemal D., Cochennec-Laureau N., Marin F., Gueguen Y., Montagnani C.
      Proc. Natl. Acad. Sci. U.S.A. 109:20986-20991(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 259-266, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
      Tissue: Shell.

    Entry informationi

    Entry nameiHEX_PINMG
    AccessioniPrimary (citable) accession number: H2A0L6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 13, 2012
    Last sequence update: March 21, 2012
    Last modified: October 1, 2014
    This is version 14 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Keywords - Technical termi

    Direct protein sequencing

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3