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Protein

Putative chitinase 2

Gene
N/A
Organism
Pinctada margaritifera (Black-lipped pearl oyster)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.Sequence analysis

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei141Proton donorPROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase

Protein family/group databases

CAZyiGH18. Glycoside Hydrolase Family 18.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative chitinase 2By similarity (EC:3.2.1.14)
Alternative name(s):
Chitinase-like protein 3By similarity
Short name:
Clp3
OrganismiPinctada margaritifera (Black-lipped pearl oyster)
Taxonomic identifieri102329 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaBivalviaPteriomorphiaPterioidaPterioideaPteriidaePinctada

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_000041797618 – 466Putative chitinase 2Sequence analysisAdd BLAST449

Expressioni

Tissue specificityi

Prismatic layer of shell (at protein level). Expressed primarily in the mantle with highest level in the mantle edge and lower level in the mantle pallium.1 Publication

Structurei

3D structure databases

SMRiH2A0L5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili395 – 447Sequence analysisAdd BLAST53

Sequence similaritiesi

Belongs to the glycosyl hydrolase 18 family.Sequence analysis

Keywords - Domaini

Coiled coil, Signal

Family and domain databases

Gene3Di3.10.50.10. 1 hit.
InterProiView protein in InterPro
IPR011583. Chitinase_II.
IPR029070. Chitinase_insertion.
IPR001223. Glyco_hydro18_cat.
IPR001579. Glyco_hydro_18_chit_AS.
IPR017853. Glycoside_hydrolase_SF.
PfamiView protein in Pfam
PF00704. Glyco_hydro_18. 1 hit.
SMARTiView protein in SMART
SM00636. Glyco_18. 1 hit.
SUPFAMiSSF51445. SSF51445. 2 hits.
SSF54556. SSF54556. 1 hit.
PROSITEiView protein in PROSITE
PS01095. CHITINASE_18. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

H2A0L5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYLTIWLVPL LAVGTWGQKF NRFCHYNSWA LSRNPQHGLV PEDIDPFLCT
60 70 80 90 100
HMILGFAEID ESGLRLKDPN HYQQQYLYQR IVRLRRINPR LNMILSVGGW
110 120 130 140 150
DKSQEGYSKL VSSRENIIFF TKWIITYLRR HDFDGLDLDW EYPTFKGSPM
160 170 180 190 200
VDKKKFVDLV ENLAYEFDIE EIPDIKWKLT LTWTADPLES VRTSAYDIKG
210 220 230 240 250
IASKVHYVNL KMYDFHGHWD DPLRVNHHSP LTSSNSPRNV NELAKTWVKA
260 270 280 290 300
GVRIEKLILG IPFFGRSFTL KTANMSAPGS PAVGPGSDFG DGIPIHNLCH
310 320 330 340 350
IIRGGTKELY LPEKKVPYIV SGSEWIGYDN PRSVMEKAQL VFNNALAGVM
360 370 380 390 400
IYSLDMDDHH GTCGKKWPMM MAVIHGLNAY MEYIDSKHKS LELTYNKKIL
410 420 430 440 450
RARVSLRNYR RRNQQGKVAE MEQRIRNLEQ ELQQSMGNMA YERQQAQAML
460
NRGVSLPPIE QQSWSW
Length:466
Mass (Da):53,985
Last modified:March 21, 2012 - v1
Checksum:iF8AE0ABB4571A13E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE610382 mRNA. Translation: CCE46156.1.

Similar proteinsi

Entry informationi

Entry nameiCHI2_PINMG
AccessioniPrimary (citable) accession number: H2A0L5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 13, 2012
Last sequence update: March 21, 2012
Last modified: May 10, 2017
This is version 19 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families