Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Histone deacetylase

Gene

HDAC3

Organism
Taeniopygia guttata (Zebra finch) (Poephila guttata)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chromatin regulatorUniRule annotation, HydrolaseUniRule annotationSAAS annotation

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotation

Enzyme and pathway databases

ReactomeiREACT_316219. Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha).
REACT_317642. Transcriptional regulation of white adipocyte differentiation.
REACT_325443. NOTCH1 Intracellular Domain Regulates Transcription.
REACT_352695. p75NTR negatively regulates cell cycle via SC1.

Names & Taxonomyi

Protein namesi
Recommended name:
Histone deacetylaseUniRule annotation (EC:3.5.1.98UniRule annotation)
Gene namesi
Name:HDAC3Imported
OrganismiTaeniopygia guttata (Zebra finch) (Poephila guttata)Imported
Taxonomic identifieri59729 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaePasseriformesPasseroideaEstrildidaeEstrildinaeTaeniopygia
ProteomesiUP000007754 Componenti: Unplaced

Subcellular locationi

  • Nucleus UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi59729.ENSTGUP00000015405.

Structurei

3D structure databases

ProteinModelPortaliH0ZXQ4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the histone deacetylase family. HD Type 1 subfamily.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00530000062889.
InParanoidiH0ZXQ4.
KOiK11404.
OMAiLFDFCSM.
OrthoDBiEOG7DNNTW.
TreeFamiTF352182.

Family and domain databases

Gene3Di3.40.800.20. 1 hit.
InterProiIPR000286. His_deacetylse.
IPR003084. His_deacetylse_1.
IPR023801. His_deacetylse_dom.
[Graphical view]
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiPF00850. Hist_deacetyl. 1 hit.
[Graphical view]
PIRSFiPIRSF037913. His_deacetylse_1. 1 hit.
PRINTSiPR01270. HDASUPER.
PR01271. HISDACETLASE.

Sequencei

Sequence statusi: Complete.

H0ZXQ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKTVDYFYD PDVANFPYGA GHPMKPHRLA LTHSLVLHYG LYKKMIVFKP
60 70 80 90 100
YQASQHDMCR FHSEDYIDFL QRVSPNNMQG FTKSLNAFNV GDDCPVFPGL
110 120 130 140 150
FEFCSRYTGA SLQGATQLNN KICDIAINWA GGLHHAKKFE ASGFCYVNDI
160 170 180 190 200
VIGILELLKY HPRVLYIDID IHHGDGVQEA FYLTDRVMTV SFHKYGNYFF
210 220 230 240 250
PGTGDMYEVG AESGRYYCLN VPLRDGIDDQ SYKHLFQPVI NQVVDYYQPT
260 270 280 290 300
CIVLQCGADS LGCDRLGCFN LSIRGHGECV EYVKSFNIPL LVLGGGGYTV
310 320 330 340 350
RNVARCWTYE TSLLVDEPIS DELPYSEYFE YFAPDFTLHP DVSTRIENQN
360 370 380 390 400
SRQYLDQIRQ TIFENLKMLN HAPSVQIHDV PSDLLSYDRT DEPDPEERGS
410 420
EENYNRPEAP NEFYDGDHDN DKESDVEI
Length:428
Mass (Da):48,964
Last modified:February 22, 2012 - v1
Checksum:iC7F30DE3EFD31180
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABQF01061867 Genomic DNA. No translation available.
ABQF01061868 Genomic DNA. No translation available.
ABQF01061869 Genomic DNA. No translation available.
ABQF01061870 Genomic DNA. No translation available.
ABQF01061871 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSTGUT00000015661; ENSTGUP00000015405; ENSTGUG00000015013.
KEGGitgu:100222558.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABQF01061867 Genomic DNA. No translation available.
ABQF01061868 Genomic DNA. No translation available.
ABQF01061869 Genomic DNA. No translation available.
ABQF01061870 Genomic DNA. No translation available.
ABQF01061871 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliH0ZXQ4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi59729.ENSTGUP00000015405.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSTGUT00000015661; ENSTGUP00000015405; ENSTGUG00000015013.
KEGGitgu:100222558.

Organism-specific databases

CTDi8841.

Phylogenomic databases

GeneTreeiENSGT00530000062889.
InParanoidiH0ZXQ4.
KOiK11404.
OMAiLFDFCSM.
OrthoDBiEOG7DNNTW.
TreeFamiTF352182.

Enzyme and pathway databases

ReactomeiREACT_316219. Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha).
REACT_317642. Transcriptional regulation of white adipocyte differentiation.
REACT_325443. NOTCH1 Intracellular Domain Regulates Transcription.
REACT_352695. p75NTR negatively regulates cell cycle via SC1.

Family and domain databases

Gene3Di3.40.800.20. 1 hit.
InterProiIPR000286. His_deacetylse.
IPR003084. His_deacetylse_1.
IPR023801. His_deacetylse_dom.
[Graphical view]
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiPF00850. Hist_deacetyl. 1 hit.
[Graphical view]
PIRSFiPIRSF037913. His_deacetylse_1. 1 hit.
PRINTSiPR01270. HDASUPER.
PR01271. HISDACETLASE.
ProtoNetiSearch...

Publicationsi

  1. Ensembl
    Submitted (JAN-2012) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiH0ZXQ4_TAEGU
AccessioniPrimary (citable) accession number: H0ZXQ4
Entry historyi
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: July 22, 2015
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.