H0ZXQ4 (H0ZXQ4_TAEGU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Histone deacetylase PIRNR PIRNR037913
EC=3.5.1.98 PIRNR PIRNR037913

Gene names

Name:

HDAC3 Ensembl ENSTGUP00000015405

Organism

Taeniopygia guttata (Zebra finch) (Poephila guttata) [Reference proteome] Ensembl ENSTGUP00000015405

Taxonomic identifier

59729 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Sauropsida › Sauria › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Passeriformes › Passeroidea › Estrildidae › Estrildinae › Taeniopygia

Protein attributes

Sequence length	428 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone. PIRNR PIRNR037913
Subcellular location	Nucleus By similarity PIRNR PIRNR037913.
Sequence similarities	Belongs to the histone deacetylase family. HD Type 1 subfamily. PIRNR PIRNR037913
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSTGUP00000015405

Ontologies

Keywords
Biological process	Transcription Transcription regulation PIRNR PIRNR037913
Cellular component	Nucleus PIRNR PIRNR037913
Molecular function	Chromatin regulator PIRNR PIRNR037913 Hydrolase SAAS SAAS000286 PIRNR PIRNR037913
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	circadian regulation of gene expression Inferred from electronic annotation. Source: Compara histone H3 deacetylation Inferred from electronic annotation. Source: GOC histone H4 deacetylation Inferred from electronic annotation. Source: GOC negative regulation of JNK cascade Inferred from electronic annotation. Source: Compara negative regulation of transcription from RNA polymerase II promoter Inferred from electronic annotation. Source: Compara regulation of mitotic cell cycle Inferred from electronic annotation. Source: Compara regulation of multicellular organism growth Inferred from electronic annotation. Source: Compara spindle assembly Inferred from electronic annotation. Source: Compara transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	spindle microtubule Inferred from electronic annotation. Source: Compara transcriptional repressor complex Inferred from electronic annotation. Source: Compara
Molecular_function	NAD-dependent histone deacetylase activity (H3-K14 specific) Inferred from electronic annotation. Source: EC NAD-dependent histone deacetylase activity (H3-K18 specific) Inferred from electronic annotation. Source: EC NAD-dependent histone deacetylase activity (H3-K9 specific) Inferred from electronic annotation. Source: EC NAD-dependent histone deacetylase activity (H4-K16 specific) Inferred from electronic annotation. Source: EC chromatin DNA binding Inferred from electronic annotation. Source: Compara transcription corepressor activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	H0ZXQ4 [UniParc]. Last modified February 22, 2012. Version 1. Checksum: C7F30DE3EFD31180	FASTA	428	48,964
	10 20 30 40 50 60 MAKTVDYFYD PDVANFPYGA GHPMKPHRLA LTHSLVLHYG LYKKMIVFKP YQASQHDMCR 70 80 90 100 110 120 FHSEDYIDFL QRVSPNNMQG FTKSLNAFNV GDDCPVFPGL FEFCSRYTGA SLQGATQLNN 130 140 150 160 170 180 KICDIAINWA GGLHHAKKFE ASGFCYVNDI VIGILELLKY HPRVLYIDID IHHGDGVQEA 190 200 210 220 230 240 FYLTDRVMTV SFHKYGNYFF PGTGDMYEVG AESGRYYCLN VPLRDGIDDQ SYKHLFQPVI 250 260 270 280 290 300 NQVVDYYQPT CIVLQCGADS LGCDRLGCFN LSIRGHGECV EYVKSFNIPL LVLGGGGYTV 310 320 330 340 350 360 RNVARCWTYE TSLLVDEPIS DELPYSEYFE YFAPDFTLHP DVSTRIENQN SRQYLDQIRQ 370 380 390 400 410 420 TIFENLKMLN HAPSVQIHDV PSDLLSYDRT DEPDPEERGS EENYNRPEAP NEFYDGDHDN DKESDVEI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome of a songbird." Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W., Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A., Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P., Velho T.A. , Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E., Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P., Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O., Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L., McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C., Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K., Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z., Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T., Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A., Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L., Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K. Nature 464:757-762(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (JAN-2012) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	ABQF01061867 Genomic DNA. No translation available. ABQF01061868 Genomic DNA. No translation available. ABQF01061869 Genomic DNA. No translation available. ABQF01061870 Genomic DNA. No translation available. ABQF01061871 Genomic DNA. No translation available.
RefSeq	XP_002189056.1. XM_002189020.2.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSTGUT00000015661; ENSTGUP00000015405; ENSTGUG00000015013.
GeneID	100222558.
KEGG	tgu:100222558.
Organism-specific databases
CTD	8841.
Phylogenomic databases
GeneTree	ENSGT00530000062889.
KO	K11404.
OMA	NFHYGPG.
Family and domain databases
Gene3D	3.40.800.20. 1 hit.
InterPro	IPR000286. His_deacetylse. IPR003084. His_deacetylse_1. IPR023801. His_deacetylse_dom. [Graphical view]
PANTHER	PTHR10625. PTHR10625. 1 hit.
Pfam	PF00850. Hist_deacetyl. 1 hit. [Graphical view]
PIRSF	PIRSF037913. His_deacetylse_1. 1 hit.
PRINTS	PR01270. HDASUPER. PR01271. HISDACETLASE.
ProtoNet	Search...

Entry information

Entry name

H0ZXQ4_TAEGU

Accession

Primary (citable) accession number: H0ZXQ4

Entry history

Integrated into UniProtKB/TrEMBL:	February 22, 2012
Last sequence update:	February 22, 2012
Last modified:	May 1, 2013
This is version 12 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)