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Protein

Histone-lysine N-methyltransferase

Gene

KMT5B

Organism
Taeniopygia guttata (Zebra finch) (Poephila guttata)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N6-methyl-L-lysine-[histone].PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferasePROSITE-ProRule annotation, Transferase
LigandS-adenosyl-L-methioninePROSITE-ProRule annotation

Enzyme and pathway databases

ReactomeiR-TGU-3214841 PKMTs methylate histone lysines

Names & Taxonomyi

Protein namesi
Recommended name:
Histone-lysine N-methyltransferasePROSITE-ProRule annotation (EC:2.1.1.43PROSITE-ProRule annotation)
Gene namesi
Name:KMT5BImported
OrganismiTaeniopygia guttata (Zebra finch) (Poephila guttata)Imported
Taxonomic identifieri59729 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaePasseriformesPasseroideaEstrildidaeEstrildinaeTaeniopygia
Proteomesi
  • UP000007754 Componenti: Chromosome 5

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini168 – 283SETInterPro annotationAdd BLAST116

Sequence similaritiesi

Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG2589 Eukaryota
ENOG410XPH8 LUCA
GeneTreeiENSGT00520000055640
KOiK11429

Family and domain databases

InterProiView protein in InterPro
IPR025790 Hist-Lys_N-MTase_Suvar4-20
IPR001214 SET_dom
PfamiView protein in Pfam
PF00856 SET, 1 hit
SMARTiView protein in SMART
SM00317 SET, 1 hit
PROSITEiView protein in PROSITE
PS51570 SAM_MT43_SUVAR420_2, 1 hit
PS50280 SET, 1 hit

Sequencei

Sequence statusi: Complete.

H0ZI28-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKWLGESKNM VVNGRRSGSK SSNDHAQTKL QHAGKENPKT GKNGVERRSS
60 70 80 90 100
RCSGASGFEG QSRYVPSSGM SAKELCENDD LATSLVLDPY LGFQTHKMNT
110 120 130 140 150
RFRPIKGRQE ELKEVIERFK KDEHLEKAFK SLTSGDWARH YFLNKNKMQE
160 170 180 190 200
RLFKEHVFIY LRMFATDSGF EILPCNRYSS EQNGAKIVAT KEWKRNDKIE
210 220 230 240 250
LLVGCIAELS EMEENMLLRH GENDFSVMYS TRKNCAQLWL GPAAFINHDC
260 270 280 290 300
RPNCKFVSTG RDTACVKALR DIEPGEEISC YYGDGFFGEN NEYCECYTCE
310 320 330 340 350
RRGTGAFKSR VGLPAPTPVI NSKYGLRETD KRLNRLKKLG DSSKNSDSQS
360 370 380 390 400
VSSNTDADTT QEKGNATNRK SSIGVKKNSK NRTLTRQSIS RIPASSNSTS
410 420 430 440 450
SKLTHINNSR VPKRLKKPAK PLLSKIKLRN QCKRPEQKNA SRKLEMGNLV
460 470 480 490 500
LKEPKVVLYK NLPIKKDKEL EGPVKVAVSS GCLTRHAARE HKLNSVKGAY
510 520 530 540 550
EHGGIAPCTY ITRRSMRTRM SLKETSDTKL EPNTLDSYQS NLTGTQSDIA
560 570 580 590 600
EQQSRALNNN VAHGPSHKGE GRCQKSDAGT SKKKSRQGKL VKPSSKTEES
610 620 630 640 650
DTMHNTPVKD EVPDLISSHS ELEERNNVVD APVGFKDCVP GSGGCSVTTD
660 670 680 690 700
NFKAKDSFRT AKSKKKRRIT RYDAQLILEN SSGIPKLTLR RRHDSSSKAN
710 720 730 740 750
DQESDGMNSS KISIKLSKDH EKDNNLYVAK LNNGFNSGSG NSSTKLKIQL
760 770 780 790 800
KREDENRGAY SEDLHENGVC CSETLSLLES RMEVDDYGHY EEETADESSS
810 820 830 840 850
EEDDEEEDDY DDEFDDFIPL PPAKRLRLIV GKDSIDIDIS SRRREDQSLR

LNA
Length:853
Mass (Da):95,823
Last modified:February 22, 2012 - v1
Checksum:i63C10B9BB3BF1C6D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABQF01002100 Genomic DNA No translation available.
ABQF01002101 Genomic DNA No translation available.
ABQF01002102 Genomic DNA No translation available.
RefSeqiXP_002199524.1, XM_002199488.3

Genome annotation databases

EnsembliENSTGUT00000010354; ENSTGUP00000010245; ENSTGUG00000009927
GeneIDi100222904
KEGGitgu:100222904

Similar proteinsi

Entry informationi

Entry nameiH0ZI28_TAEGU
AccessioniPrimary (citable) accession number: H0ZI28
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: March 28, 2018
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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