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H0YNP5

- H0YNP5_HUMAN

UniProt

H0YNP5 - H0YNP5_HUMAN

Protein

Annexin

Gene

ANXA2

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
  1. Functioni

    GO - Molecular functioni

    1. calcium-dependent phospholipid binding Source: UniProtKB-KW
    2. calcium ion binding Source: InterPro
    3. phospholipase inhibitor activity Source: InterPro

    Keywords - Ligandi

    Calcium, Calcium/phospholipid-bindingUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    AnnexinUniRule annotation
    Gene namesi
    Name:ANXA2Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 15

    Organism-specific databases

    HGNCiHGNC:537. ANXA2.

    PTM / Processingi

    Proteomic databases

    PRIDEiH0YNP5.

    Expressioni

    Gene expression databases

    ArrayExpressiH0YNP5.
    BgeeiH0YNP5.

    Structurei

    3D structure databases

    ProteinModelPortaliH0YNP5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domaini

    A pair of annexin repeats may form one binding site for calcium and phospholipid.UniRule annotation

    Sequence similaritiesi

    Belongs to the annexin family.UniRule annotation
    Contains 2 annexin repeats.UniRule annotation

    Keywords - Domaini

    AnnexinUniRule annotationSAAS annotation, RepeatUniRule annotationSAAS annotation

    Family and domain databases

    Gene3Di1.10.220.10. 2 hits.
    InterProiIPR001464. Annexin.
    IPR018502. Annexin_repeat.
    IPR018252. Annexin_repeat_CS.
    IPR002389. AnnexinII.
    [Graphical view]
    PANTHERiPTHR10502:SF18. PTHR10502:SF18. 1 hit.
    PfamiPF00191. Annexin. 2 hits.
    [Graphical view]
    PRINTSiPR00196. ANNEXIN.
    SMARTiSM00335. ANX. 1 hit.
    [Graphical view]
    PROSITEiPS00223. ANNEXIN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    H0YNP5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSTVHEILCK LSLEGDELAS ALKSALSGHL ETVILGLLKT PAQYDASELK    50
    ASMKGLGTDE DSLIEIICSR TNQELQEINR VYKEMYKTDL EKDIISDTSG 100
    DFRKLMVALA KGRRAEDGSV IDYELIDQDA RDLYDAGVKR KGTDVPKWIS 150
    IMTERSVPHL QKVFDRYKSY SPYDM 175
    Length:175
    Mass (Da):19,727
    Last modified:February 22, 2012 - v1
    Checksum:i4EC242122752954C
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei175 – 1751Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC087385 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000558132; ENSP00000454096; ENSG00000182718.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC087385 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali H0YNP5.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi H0YNP5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000558132 ; ENSP00000454096 ; ENSG00000182718 .

    Organism-specific databases

    HGNCi HGNC:537. ANXA2.
    GenAtlasi Search...

    Miscellaneous databases

    ChiTaRSi ANXA2. human.
    NextBioi 35525101.

    Gene expression databases

    ArrayExpressi H0YNP5.
    Bgeei H0YNP5.

    Family and domain databases

    Gene3Di 1.10.220.10. 2 hits.
    InterProi IPR001464. Annexin.
    IPR018502. Annexin_repeat.
    IPR018252. Annexin_repeat_CS.
    IPR002389. AnnexinII.
    [Graphical view ]
    PANTHERi PTHR10502:SF18. PTHR10502:SF18. 1 hit.
    Pfami PF00191. Annexin. 2 hits.
    [Graphical view ]
    PRINTSi PR00196. ANNEXIN.
    SMARTi SM00335. ANX. 1 hit.
    [Graphical view ]
    PROSITEi PS00223. ANNEXIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Analysis of the DNA sequence and duplication history of human chromosome 15."
      Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K., Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N., Abouelleil A.
      , Arachchi H.M., Baradarani L., Birditt B., Bloom S., Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K., DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M., Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.
      Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. Ensembl
      Submitted (JAN-2012) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiH0YNP5_HUMAN
    AccessioniPrimary (citable) accession number: H0YNP5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 22, 2012
    Last sequence update: February 22, 2012
    Last modified: October 1, 2014
    This is version 18 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3