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Protein

Annexin

Gene

ANXA2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandCalcium, Calcium/phospholipid-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
AnnexinUniRule annotation
Gene namesi
Name:ANXA2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 15

Organism-specific databases

EuPathDBiHostDB:ENSG00000182718.16.
HGNCiHGNC:537. ANXA2.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000182718.

PTM / Processingi

Proteomic databases

MaxQBiH0YNP5.
PaxDbiH0YNP5.
PeptideAtlasiH0YNP5.
PRIDEiH0YNP5.

Expressioni

Gene expression databases

BgeeiENSG00000182718.
ExpressionAtlasiH0YNP5. baseline and differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliH0YNP5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domaini

A pair of annexin repeats may form one binding site for calcium and phospholipid.UniRule annotation

Sequence similaritiesi

Belongs to the annexin family.UniRule annotation

Keywords - Domaini

AnnexinUniRule annotationSAAS annotation, RepeatUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0819. Eukaryota.
ENOG410XPUN. LUCA.
GeneTreeiENSGT00760000118972.

Family and domain databases

Gene3Di1.10.220.10. 3 hits.
InterProiView protein in InterPro
IPR001464. Annexin.
IPR018502. Annexin_repeat.
IPR018252. Annexin_repeat_CS.
IPR037104. Annexin_sf.
IPR002389. ANX2.
PANTHERiPTHR10502:SF18. PTHR10502:SF18. 2 hits.
PfamiView protein in Pfam
PF00191. Annexin. 2 hits.
PRINTSiPR00196. ANNEXIN.
SMARTiView protein in SMART
SM00335. ANX. 1 hit.
PROSITEiView protein in PROSITE
PS00223. ANNEXIN. 1 hit.

Sequencei

Sequence statusi: Fragment.

H0YNP5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTVHEILCK LSLEGDELAS ALKSALSGHL ETVILGLLKT PAQYDASELK
60 70 80 90 100
ASMKGLGTDE DSLIEIICSR TNQELQEINR VYKEMYKTDL EKDIISDTSG
110 120 130 140 150
DFRKLMVALA KGRRAEDGSV IDYELIDQDA RDLYDAGVKR KGTDVPKWIS
160 170
IMTERSVPHL QKVFDRYKSY SPYDM
Length:175
Mass (Da):19,727
Last modified:February 22, 2012 - v1
Checksum:i4EC242122752954C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei175Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC087385 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000558132; ENSP00000454096; ENSG00000182718.
UCSCiuc059jwo.1. human.

Similar proteinsi

Entry informationi

Entry nameiH0YNP5_HUMAN
AccessioniPrimary (citable) accession number: H0YNP5
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: October 25, 2017
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported