UniProtKB - H0YLS5 (H0YLS5_HUMAN)
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Protein
Submitted name:
Nuclear receptor ROR-alpha
Gene
RORA
Organism
Homo sapiens (Human)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 72 – 147 | Nuclear receptorPROSITE-ProRule annotationAdd BLAST | 76 |
GO - Molecular functioni
- DNA binding transcription factor activity Source: InterPro
- sequence-specific DNA binding Source: InterPro
- zinc ion binding Source: InterPro
GO - Biological processi
- transcription, DNA-templated Source: UniProtKB-UniRule
Keywordsi
Molecular function | DNA-bindingPROSITE-ProRule annotationSAAS annotation |
Biological process | Transcription, Transcription regulationPROSITE-ProRule annotationSAAS annotation |
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Nuclear receptor ROR-alphaImported |
Gene namesi | Name:RORAImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000069667.15 |
HGNCi | HGNC:10258 RORA |
Subcellular locationi
Keywords - Cellular componenti
NucleusPROSITE-ProRule annotationSAAS annotationExpressioni
Gene expression databases
Bgeei | ENSG00000069667 |
ExpressionAtlasi | H0YLS5 baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 72 – 147 | Nuclear receptorInterPro annotationAdd BLAST | 76 |
Keywords - Domaini
Zinc-fingerPROSITE-ProRule annotationSAAS annotationPhylogenomic databases
eggNOGi | KOG4216 Eukaryota ENOG410XUGR LUCA |
GeneTreei | ENSGT00870000136388 |
Family and domain databases
Gene3Di | 3.30.50.101 hit |
InterProi | View protein in InterPro IPR001628 Znf_hrmn_rcpt IPR013088 Znf_NHR/GATA |
Pfami | View protein in Pfam PF00105 zf-C4, 1 hit |
PRINTSi | PR00047 STROIDFINGER |
SMARTi | View protein in SMART SM00399 ZnF_C4, 1 hit |
PROSITEi | View protein in PROSITE PS00031 NUCLEAR_REC_DBD_1, 1 hit PS51030 NUCLEAR_REC_DBD_2, 1 hit |
i Sequence
Sequence statusi: Fragment.
H0YLS5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRVTVAPQTK PVFSTNELAH LSPPSAPASQ RESGVGLRAS CPTEWGQKVV
60 70 80 90 100
RGAFRGALRA EKRPAATAQI EIIPCKICGD KSSGIHYGVI TCEGCKGFFR
110 120 130 140 150
RSQQSNATYS CPRQKNCLID RTSRNRCQHC RLQKCLAVGM SRDAVKFGRM
SKK
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 153 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC087385 Genomic DNA No translation available. AC107241 Genomic DNA No translation available. KC877548 Genomic DNA No translation available. KC877551 Genomic DNA No translation available. KC877555 Genomic DNA No translation available. KF456062 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000559343; ENSP00000453322; ENSG00000069667 |
UCSCi | uc059jyl.1 human |
Similar proteinsi
Entry informationi
Entry namei | H0YLS5_HUMAN | |
Accessioni | H0YLS5Primary (citable) accession number: H0YLS5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 22, 2012 |
Last sequence update: | February 22, 2012 | |
Last modified: | March 28, 2018 | |
This is version 48 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |