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Protein
Submitted name:

Nuclear receptor ROR-alpha

Gene

RORA

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi72 – 147Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear receptor ROR-alphaImported
Gene namesi
Name:RORAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 15

Organism-specific databases

EuPathDBiHostDB:ENSG00000069667.15
HGNCiHGNC:10258 RORA

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000069667

PTM / Processingi

Proteomic databases

PeptideAtlasiH0YLS5
PRIDEiH0YLS5

Expressioni

Gene expression databases

BgeeiENSG00000069667
ExpressionAtlasiH0YLS5 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0YLS5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini72 – 147Nuclear receptorInterPro annotationAdd BLAST76

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG4216 Eukaryota
ENOG410XUGR LUCA
GeneTreeiENSGT00870000136388

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00105 zf-C4, 1 hit
PRINTSiPR00047 STROIDFINGER
SMARTiView protein in SMART
SM00399 ZnF_C4, 1 hit
PROSITEiView protein in PROSITE
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequencei

Sequence statusi: Fragment.

H0YLS5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRVTVAPQTK PVFSTNELAH LSPPSAPASQ RESGVGLRAS CPTEWGQKVV
60 70 80 90 100
RGAFRGALRA EKRPAATAQI EIIPCKICGD KSSGIHYGVI TCEGCKGFFR
110 120 130 140 150
RSQQSNATYS CPRQKNCLID RTSRNRCQHC RLQKCLAVGM SRDAVKFGRM

SKK
Length:153
Mass (Da):16,799
Last modified:February 22, 2012 - v1
Checksum:i5D7973129AD57FC8
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei153Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC087385 Genomic DNA No translation available.
AC107241 Genomic DNA No translation available.
KC877548 Genomic DNA No translation available.
KC877551 Genomic DNA No translation available.
KC877555 Genomic DNA No translation available.
KF456062 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000559343; ENSP00000453322; ENSG00000069667
UCSCiuc059jyl.1 human

Similar proteinsi

Entry informationi

Entry nameiH0YLS5_HUMAN
AccessioniPrimary (citable) accession number: H0YLS5
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: May 23, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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