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Protein
Submitted name:

Aquaporin-9

Gene

AQP9

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Biological processTransportUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Aquaporin-9Imported
Gene namesi
Name:AQP9Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 15

Organism-specific databases

EuPathDBiHostDB:ENSG00000103569.9.
HGNCiHGNC:643. AQP9.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei6 – 30HelicalSequence analysisAdd BLAST25
Transmembranei37 – 60HelicalSequence analysisAdd BLAST24
Transmembranei93 – 114HelicalSequence analysisAdd BLAST22
Transmembranei126 – 144HelicalSequence analysisAdd BLAST19
Transmembranei178 – 200HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000103569.

PTM / Processingi

Proteomic databases

PaxDbiH0YK62.
PeptideAtlasiH0YK62.

Expressioni

Gene expression databases

BgeeiENSG00000103569.
ExpressionAtlasiH0YK62. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliH0YK62.
SMRiH0YK62.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MIP/aquaporin (TC 1.A.8) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0224. Eukaryota.
COG0580. LUCA.
GeneTreeiENSGT00510000046311.

Family and domain databases

CDDicd00333. MIP. 1 hit.
Gene3Di1.20.1080.10. 1 hit.
InterProiView protein in InterPro
IPR023271. Aquaporin-like.
IPR015685. Aquaporin_9.
IPR000425. MIP.
IPR022357. MIP_CS.
PANTHERiPTHR43829:SF6. PTHR43829:SF6. 1 hit.
PfamiView protein in Pfam
PF00230. MIP. 1 hit.
PRINTSiPR02021. AQUAPORIN9.
PR00783. MINTRINSICP.
SUPFAMiSSF81338. SSF81338. 1 hit.
TIGRFAMsiTIGR00861. MIP. 1 hit.
PROSITEiView protein in PROSITE
PS00221. MIP. 1 hit.

Sequencei

Sequence statusi: Complete.

H0YK62-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVAMAIYVA GGVSGGHINP AVSLAMCLFG RMKWFKLPFY VGAQFLGAFV
60 70 80 90 100
GAATVFGIYY DGLMSFAGGK LLIVGENATA HIFATYPAPY LSLANAFADQ
110 120 130 140 150
VVATMILLII VFAIFDSRNL GAPRGLEPIA IGLLIIVIAS SLGLNSGCAM
160 170 180 190 200
NPARDLSPRL FTALAGWGFE VFRAGNNFWW IPVVGPLVGA VIGGLIYVLV
210 220 230
IEIHHPEPDS VFKTEQSEDK PEKYELSVIM
Length:230
Mass (Da):24,546
Last modified:February 22, 2012 - v1
Checksum:i8CAD0CA08EC56EFC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC025431 Genomic DNA. No translation available.
AC066616 Genomic DNA. No translation available.
RefSeqiNP_001307565.1. NM_001320636.1.
UniGeneiHs.104624.

Genome annotation databases

EnsembliENST00000558772; ENSP00000452673; ENSG00000103569.
GeneIDi366.
UCSCiuc010ugx.2. human.

Similar proteinsi

Entry informationi

Entry nameiH0YK62_HUMAN
AccessioniPrimary (citable) accession number: H0YK62
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: November 22, 2017
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported