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Protein
Submitted name:

Bcl-2-like protein 2

Gene

BCL2L2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Bcl-2-like protein 2Imported
Gene namesi
Name:BCL2L2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

HGNCiHGNC:995. BCL2L2.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei113 – 134HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000129473.

PTM / Processingi

Proteomic databases

MaxQBiH0YJC7.
PaxDbiH0YJC7.
PeptideAtlasiH0YJC7.

Expressioni

Gene expression databases

ExpressionAtlasiH0YJC7. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000250405.

Structurei

3D structure databases

ProteinModelPortaliH0YJC7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG4209. Eukaryota.
ENOG4111PFV. LUCA.
GeneTreeiENSGT00530000062935.

Family and domain databases

InterProiIPR013280. Apop_reg_BclW.
IPR002475. Bcl2-like.
IPR020717. Bcl2_BH1_motif_CS.
IPR020726. Bcl2_BH2_motif_CS.
IPR026298. Blc2_fam.
[Graphical view]
PANTHERiPTHR11256. PTHR11256. 1 hit.
PTHR11256:SF13. PTHR11256:SF13. 1 hit.
PfamiPF00452. Bcl-2. 1 hit.
[Graphical view]
PRINTSiPR01865. APOPREGBCLW.
PR01862. BCL2FAMILY.
PROSITEiPS50062. BCL2_FAMILY. 1 hit.
PS01080. BH1. 1 hit.
PS01258. BH2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

H0YJC7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
XRTFSDLAAQ LHVTPGSAQQ RFTQVSDELF QGGPNWGRLV AFFVFGAALC
60 70 80 90 100
AESVNKEMEP LVGQVQEWMV AYLETQLADW IHSSGGWAEF TALYGDGALE
110 120 130 140 150
EARRLREGNW ASVRTVLTGA VALGALVWST LFTLPSTTGH ISLLAFPGTF
160
SQEELQGPWP GYQNALL
Length:167
Mass (Da):18,232
Last modified:February 22, 2012 - v1
Checksum:i5C8D006FFE396CCB
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL049829 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000556599; ENSP00000451197; ENSG00000129473.
UCSCiuc058zqo.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL049829 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliH0YJC7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000250405.

Proteomic databases

MaxQBiH0YJC7.
PaxDbiH0YJC7.
PeptideAtlasiH0YJC7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000556599; ENSP00000451197; ENSG00000129473.
UCSCiuc058zqo.1. human.

Organism-specific databases

HGNCiHGNC:995. BCL2L2.
OpenTargetsiENSG00000129473.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4209. Eukaryota.
ENOG4111PFV. LUCA.
GeneTreeiENSGT00530000062935.

Miscellaneous databases

ChiTaRSiBCL2L2. human.

Gene expression databases

ExpressionAtlasiH0YJC7. baseline and differential.

Family and domain databases

InterProiIPR013280. Apop_reg_BclW.
IPR002475. Bcl2-like.
IPR020717. Bcl2_BH1_motif_CS.
IPR020726. Bcl2_BH2_motif_CS.
IPR026298. Blc2_fam.
[Graphical view]
PANTHERiPTHR11256. PTHR11256. 1 hit.
PTHR11256:SF13. PTHR11256:SF13. 1 hit.
PfamiPF00452. Bcl-2. 1 hit.
[Graphical view]
PRINTSiPR01865. APOPREGBCLW.
PR01862. BCL2FAMILY.
PROSITEiPS50062. BCL2_FAMILY. 1 hit.
PS01080. BH1. 1 hit.
PS01258. BH2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiH0YJC7_HUMAN
AccessioniPrimary (citable) accession number: H0YJC7
Entry historyi
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: November 2, 2016
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.