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H0YHK3

- H0YHK3_HUMAN

UniProt

H0YHK3 - H0YHK3_HUMAN

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Protein
Submitted name:

Liprin-alpha-2

Gene

PPFIA2

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Biological processi

  1. cell-matrix adhesion Source: InterPro
  2. signal transduction Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Liprin-alpha-2Imported
Gene namesi
Name:PPFIA2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 12

Organism-specific databases

HGNCiHGNC:9246. PPFIA2.

Subcellular locationi

GO - Cellular componenti

  1. presynaptic active zone Source: InterPro
Complete GO annotation...

Expressioni

Gene expression databases

ExpressionAtlasiH0YHK3. baseline.

Structurei

3D structure databases

ProteinModelPortaliH0YHK3.
SMRiH0YHK3. Positions 718-1029.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000119138.

Family and domain databases

Gene3Di1.10.150.50. 2 hits.
InterProiIPR029515. Liprin.
IPR001660. SAM.
IPR013761. SAM/pointed.
IPR011510. SAM_2.
IPR021129. SAM_type1.
[Graphical view]
PANTHERiPTHR12587. PTHR12587. 1 hit.
PfamiPF00536. SAM_1. 2 hits.
PF07647. SAM_2. 1 hit.
[Graphical view]
SMARTiSM00454. SAM. 3 hits.
[Graphical view]
SUPFAMiSSF47769. SSF47769. 3 hits.
PROSITEiPS50105. SAM_DOMAIN. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H0YHK3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTVVKRQAQS PSGVSSEVEV LKALKSLFEH HKALDEKVRE RLRVSLERVS
60 70 80 90 100
ALEEELAAAN QEIVALREQN VHIQRKMASS EGSTESEHLE GMEPGQKVHE
110 120 130 140 150
KRLSNGSIDS TDETSQIVEL QELLEKQNYE MAQMKERLAA LSSRVGEVEQ
160 170 180 190 200
EAETARKDLI KTEEMNTKYQ RDIREAMAQK EDMEERITTL EKRYLSAQRE
210 220 230 240 250
STSIHDMNDK LENELANKEA ILRQMEEKNR QLQERLELAE QKLQQTMRKA
260 270 280 290 300
ETLPEVEAEL AQRIAALTKA EERHGNIEER MRHLEGQLEE KNQELQRARQ
310 320 330 340 350
REKMNEEHNK RLSDTVDRLL TESNERLQLH LKERMAALEE KNVLIQESET
360 370 380 390 400
FRKNLEESLH DKERLAEEIE KLRSELDQLK MRTGSLIEPT IPRTHLDTSA
410 420 430 440 450
ELRYSVGSLV DSQSDYRTTK VIRRPRRGRM GVRRDEPKVK SLGDHEWNRT
460 470 480 490 500
QQIGVLSSHP FESDTEMSDI DDDDRETIFS SMDLLSPSGH SDAQTLAMML
510 520 530 540 550
QEQLDAINKE IRLIQEEKES TELRAEEIEN RVASVSLEGL NLARVHPGTS
560 570 580 590 600
ITASVTASSL ASSSPPSGHS TPKLTPRSPA REMDRMGVMT LPSDLRKHRR
610 620 630 640 650
KIAVVEEDGR EDKATIKCET SPPPTPRALR MTHTLPSSYH NDARSSLSVS
660 670 680 690 700
LEPESLGLGS ANSSQDSLHK APKKKGIKSS IGRLFGKKEK ARLGQLRGFM
710 720 730 740 750
ETEAAAQESL GLGKLGTQAE KDRRLKKKHE LLEEARRKGL PFAQWDGPTV
760 770 780 790 800
VAWLELWLGM PAWYVAACRA NVKSGAIMSA LSDTEIQREI GISNPLHRLK
810 820 830 840 850
LRLAIQEMVS LTSPSAPPTS RTPSGNVWVT HEEMENLAAP AKTKESEEGS
860 870 880 890 900
WAQCPVFLQT LAYGDMNHEW IGNEWLPSLG LPQYRSYFME CLVDARMLDH
910 920 930 940 950
LTKKDLRVHL KMVDSFHRTS LQYGIMCLKR LNYDRKELER RREASQHEIK
960 970 980 990 1000
DVLVWSNDRV IRWIQAIGLR EYANNILESG VHGSLIALDE NFDYSSLALL
1010 1020 1030 1040 1050
LQIPTQNTQA RQILEREYNN LLALGTERRL DESDDKNFRR GSTWRRQFPP
1060 1070 1080 1090 1100
REVHGISMMP GSSETLPAGF RLTTTSGQSR KMTTDVASSR LQRLDNSTVR

TYSC
Length:1,104
Mass (Da):125,906
Last modified:June 26, 2013 - v2
Checksum:iBA107C7C0ECBFB3B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC011316 Genomic DNA. No translation available.
AC069228 Genomic DNA. No translation available.
AC078920 Genomic DNA. No translation available.
AC079363 Genomic DNA. No translation available.
AC079408 Genomic DNA. No translation available.
RefSeqiNP_001269465.1. NM_001282536.1.
UniGeneiHs.506216.
Hs.737103.

Genome annotation databases

EnsembliENST00000550359; ENSP00000447273; ENSG00000139220.
GeneIDi8499.
KEGGihsa:8499.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC011316 Genomic DNA. No translation available.
AC069228 Genomic DNA. No translation available.
AC078920 Genomic DNA. No translation available.
AC079363 Genomic DNA. No translation available.
AC079408 Genomic DNA. No translation available.
RefSeqi NP_001269465.1. NM_001282536.1.
UniGenei Hs.506216.
Hs.737103.

3D structure databases

ProteinModelPortali H0YHK3.
SMRi H0YHK3. Positions 718-1029.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000550359 ; ENSP00000447273 ; ENSG00000139220 .
GeneIDi 8499.
KEGGi hsa:8499.

Organism-specific databases

CTDi 8499.
HGNCi HGNC:9246. PPFIA2.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00760000119138.

Miscellaneous databases

ChiTaRSi PPFIA2. human.
GenomeRNAii 8499.
NextBioi 35523228.

Gene expression databases

ExpressionAtlasi H0YHK3. baseline.

Family and domain databases

Gene3Di 1.10.150.50. 2 hits.
InterProi IPR029515. Liprin.
IPR001660. SAM.
IPR013761. SAM/pointed.
IPR011510. SAM_2.
IPR021129. SAM_type1.
[Graphical view ]
PANTHERi PTHR12587. PTHR12587. 1 hit.
Pfami PF00536. SAM_1. 2 hits.
PF07647. SAM_2. 1 hit.
[Graphical view ]
SMARTi SM00454. SAM. 3 hits.
[Graphical view ]
SUPFAMi SSF47769. SSF47769. 3 hits.
PROSITEi PS50105. SAM_DOMAIN. 3 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The finished DNA sequence of human chromosome 12."
    Baylor College of Medicine Human Genome Sequencing Center Sequence Production Team
    Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.
    , Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Montgomery K.T., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H., Draper H., Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S., Kelly S.H., Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J., Santibanez J., Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q., Williams G.A., Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V., Bailey M., Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E., Burkett C.E., Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K., Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D., Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., Dathorne S.R., David R., Davis C.M., Davy-Carroll L., Deshazo D.R., Donlin J.E., D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., Escotto M., Flagg N., Forbes L.D., Gabisi A.M., Garza M., Hamilton C., Henderson N., Hernandez O., Hines S., Hogues M.E., Huang M., Idlebird D.G., Johnson R., Jolivet A., Jones S., Kagan R., King L.M., Leal B., Lebow H., Lee S., LeVan J.M., Lewis L.C., London P., Lorensuhewa L.M., Loulseged H., Lovett D.A., Lucier A., Lucier R.L., Ma J., Madu R.C., Mapua P., Martindale A.D., Martinez E., Massey E., Mawhiney S., Meador M.G., Mendez S., Mercado C., Mercado I.C., Merritt C.E., Miner Z.L., Minja E., Mitchell T., Mohabbat F., Mohabbat K., Montgomery B., Moore N., Morris S., Munidasa M., Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O., Nwokenkwo S., Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J., Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A., Perrin W., Pickens A., Primus E.L., Pu L.L., Puazo M., Quiles M.M., Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I., Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A., Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., Trejos Z.Y., Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., Vera V.A., Villasana D.M., Wang L., Ward-Moore S., Warren J.T., Wei X., White F., Williamson A.L., Wleczyk R., Wooden H.S., Wooden S.H., Yen J., Yoon L., Yoon V., Zorrilla S.E., Nelson D., Kucherlapati R., Weinstock G., Gibbs R.A., null.
    Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JAN-2012) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiH0YHK3_HUMAN
AccessioniPrimary (citable) accession number: H0YHK3
Entry historyi
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: June 26, 2013
Last modified: October 29, 2014
This is version 24 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3