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Protein
Submitted name:

Alpha-2-macroglobulin

Gene

A2M

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha-2-macroglobulinImported
Gene namesi
Name:A2MImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

HGNCiHGNC:7. A2M.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000175899.

PTM / Processingi

Proteomic databases

MaxQBiH0YFH1.
PaxDbiH0YFH1.
PeptideAtlasiH0YFH1.
PRIDEiH0YFH1.

Expressioni

Gene expression databases

BgeeiENSG00000175899.
ExpressionAtlasiH0YFH1. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000323929.

Structurei

3D structure databases

ProteinModelPortaliH0YFH1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 62A2M_N_2InterPro annotationAdd BLAST50

Phylogenomic databases

eggNOGiKOG1366. Eukaryota.
ENOG410XRED. LUCA.
GeneTreeiENSGT00760000118982.

Family and domain databases

InterProiIPR011625. A2M_N_2.
[Graphical view]
PfamiPF07703. A2M_N_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

H0YFH1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
NGGTLLGLKK LSFYYLIMAK GGIVRTGTHG LLVKQEDMKG HFSISIPVKS
60 70
DIAPVARFTT CYQKRTSLAS LGL
Length:73
Mass (Da):7,899
Last modified:February 22, 2012 - v1
Checksum:iB6B84D4D97A8CF2E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007436 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000546069; ENSP00000438599; ENSG00000175899.
UCSCiuc058kzs.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007436 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliH0YFH1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000323929.

Proteomic databases

MaxQBiH0YFH1.
PaxDbiH0YFH1.
PeptideAtlasiH0YFH1.
PRIDEiH0YFH1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000546069; ENSP00000438599; ENSG00000175899.
UCSCiuc058kzs.1. human.

Organism-specific databases

HGNCiHGNC:7. A2M.
OpenTargetsiENSG00000175899.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1366. Eukaryota.
ENOG410XRED. LUCA.
GeneTreeiENSGT00760000118982.

Miscellaneous databases

ChiTaRSiA2M. human.

Gene expression databases

BgeeiENSG00000175899.
ExpressionAtlasiH0YFH1. baseline and differential.

Family and domain databases

InterProiIPR011625. A2M_N_2.
[Graphical view]
PfamiPF07703. A2M_N_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiH0YFH1_HUMAN
AccessioniPrimary (citable) accession number: H0YFH1
Entry historyi
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: November 2, 2016
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.