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Protein
Submitted name:

Trifunctional enzyme subunit alpha, mitochondrial

Gene

HADHA

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Trifunctional enzyme subunit alpha, mitochondrialImported
Gene namesi
Name:HADHAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000084754.10.
HGNCiHGNC:4801. HADHA.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000084754.

PTM / Processingi

Proteomic databases

MaxQBiH0YFD6.
PeptideAtlasiH0YFD6.
PRIDEiH0YFD6.

Expressioni

Gene expression databases

BgeeiENSG00000084754.
ExpressionAtlasiH0YFD6. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliH0YFD6.
SMRiH0YFD6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 1253HCDHInterPro annotationAdd BLAST96

Phylogenomic databases

GeneTreeiENSGT00880000137923.

Family and domain databases

Gene3Di1.10.1040.10. 2 hits.
InterProiView protein in InterPro
IPR006180. 3-OHacyl-CoA_DH_CS.
IPR006108. 3HC_DH_C.
IPR008927. 6-PGluconate_DH-like_C_sf.
IPR013328. 6PGD_dom2.
PfamiView protein in Pfam
PF00725. 3HCDH. 1 hit.
SUPFAMiSSF48179. SSF48179. 2 hits.
PROSITEiView protein in PROSITE
PS00067. 3HCDH. 1 hit.

Sequencei

Sequence statusi: Fragment.

H0YFD6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
EKTSKDTSAS AVAVGLKQGK VIIVVKDGPG FYTTRCLAPM MSEVIRILQE
60 70 80 90 100
GVDPKKLDSL TTSFGFPVGA ATLVDEVGVD VAKHVAEDLG KVFGERFGGG
110 120 130 140 150
NPELLTQMVS KGFLGRKSGK GFYIYQEGVK RKDLNSDMDS ILASLKLPPK
160 170 180 190 200
SEVSSDEDIQ FRLVTRFVNE AVMCLQEGIL ATPAEGDIGA VFGLGFPPCL
210 220 230 240 250
GGWSRRLGRK LTLAWSPCCV SFNEVLFLYS GPFRFVDLYG AQKIVDRLKK
Length:250
Mass (Da):27,108
Last modified:February 22, 2012 - v1
Checksum:iCCC001BAFB843C52
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei250Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010896 Genomic DNA. No translation available.
AC011742 Genomic DNA. No translation available.
KF510807 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000492433; ENSP00000438039; ENSG00000084754.
UCSCiuc061hgx.1. human.

Similar proteinsi

Entry informationi

Entry nameiH0YFD6_HUMAN
AccessioniPrimary (citable) accession number: H0YFD6
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: November 22, 2017
This is version 37 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported