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H0YEJ5

- H0YEJ5_HUMAN

UniProt

H0YEJ5 - H0YEJ5_HUMAN

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Protein
Submitted name:

7-dehydrocholesterol reductase

Gene

DHCR7

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
7-dehydrocholesterol reductaseImported
Gene namesi
Name:DHCR7Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 11

Organism-specific databases

HGNCiHGNC:2860. DHCR7.

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiH0YEJ5.
ExpressionAtlasiH0YEJ5. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliH0YEJ5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000000417.
OMAiWWATTSS.

Family and domain databases

InterProiIPR001171. Ergosterol_biosynth_ERG4_ERG24.
IPR018083. Sterol_reductase_CS.
[Graphical view]
PfamiPF01222. ERG4_ERG24. 1 hit.
[Graphical view]
PROSITEiPS01017. STEROL_REDUCT_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

H0YEJ5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
TGNFFYNYMM GIEFNPRIGK WFDFKLFFNG RPGIVAWTLI NLSFAAKQRE
60 70 80 90 100
LHSHVTNAMV LVNVLQAIYV IDFFWNETWY LKTIDICHDH FGWYLGWGDC
110 120 130 140 150
VWLPYLYTLQ KRTRRQGVCQ RQSWGLTPGR WAPEPTLLSS PWAKHRLTPS
160 170 180 190 200
PSPPRVCTWC TTPCSCPPRT PWASCCWAWW ATTSSGWPTT RRTCSAARMG
210 220 230 240
AASSGAGSPR SSSAPTHPPM GRGTTASCWC RASGAWPATS TTSAT
Length:245
Mass (Da):27,644
Last modified:February 22, 2012 - v1
Checksum:i9C99C1D658E396C5
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP002387 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000525137; ENSP00000435956; ENSG00000172893.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP002387 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali H0YEJ5.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000525137 ; ENSP00000435956 ; ENSG00000172893 .

Organism-specific databases

HGNCi HGNC:2860. DHCR7.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00390000000417.
OMAi WWATTSS.

Miscellaneous databases

NextBioi 35522430.

Gene expression databases

Bgeei H0YEJ5.
ExpressionAtlasi H0YEJ5. baseline and differential.

Family and domain databases

InterProi IPR001171. Ergosterol_biosynth_ERG4_ERG24.
IPR018083. Sterol_reductase_CS.
[Graphical view ]
Pfami PF01222. ERG4_ERG24. 1 hit.
[Graphical view ]
PROSITEi PS01017. STEROL_REDUCT_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JAN-2012) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiH0YEJ5_HUMAN
AccessioniPrimary (citable) accession number: H0YEJ5
Entry historyi
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: October 29, 2014
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3