H0YEJ5 (H0YEJ5_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
7-dehydrocholesterol reductase Ensembl ENSP00000435956

Gene names

Name:

DHCR7 Ensembl ENSP00000435956

Organism

Homo sapiens (Human) [Reference proteome] Ensembl ENSP00000435956

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	245 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000435956

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	membrane Inferred from electronic annotation. Source: InterPro
Molecular_function	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	Ensembl ENSP00000435956

Sequences

	Sequence		Length	Mass (Da)
	H0YEJ5 [UniParc]. Last modified February 22, 2012. Version 1. Checksum: 9C99C1D658E396C5	FASTA	245	27,644
	10 20 30 40 50 60 TGNFFYNYMM GIEFNPRIGK WFDFKLFFNG RPGIVAWTLI NLSFAAKQRE LHSHVTNAMV 70 80 90 100 110 120 LVNVLQAIYV IDFFWNETWY LKTIDICHDH FGWYLGWGDC VWLPYLYTLQ KRTRRQGVCQ 130 140 150 160 170 180 RQSWGLTPGR WAPEPTLLSS PWAKHRLTPS PSPPRVCTWC TTPCSCPPRT PWASCCWAWW 190 200 210 220 230 240 ATTSSGWPTT RRTCSAARMG AASSGAGSPR SSSAPTHPPM GRGTTASCWC RASGAWPATS TTSAT

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Human chromosome 11 DNA sequence and analysis including novel gene identification." Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K., Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T., Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G. , Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C., Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A., Hattori M., Rogers J., Lander E.S., Sakaki Y. Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (JAN-2012) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP002387 Genomic DNA. No translation available.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000525137; ENSP00000435956; ENSG00000172893.
Organism-specific databases
HGNC	HGNC:2860. DHCR7.
GenAtlas	Search...
Gene expression databases
ArrayExpress	H0YEJ5.
Bgee	H0YEJ5.
Family and domain databases
InterPro	IPR001171. Ergosterol_biosynth_ERG4_ERG24. IPR018083. Sterol_reductase_CS. [Graphical view]
Pfam	PF01222. ERG4_ERG24. 1 hit. [Graphical view]
PROSITE	PS01017. STEROL_REDUCT_1. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35522430.

Entry information

Entry name

H0YEJ5_HUMAN

Accession

Primary (citable) accession number: H0YEJ5

Entry history

Integrated into UniProtKB/TrEMBL:	February 22, 2012
Last sequence update:	February 22, 2012
Last modified:	April 3, 2013
This is version 7 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.