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Protein
Submitted name:

7-dehydrocholesterol reductase

Gene

DHCR7

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
7-dehydrocholesterol reductaseImported
Gene namesi
Name:DHCR7Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000172893.15
HGNCiHGNC:2860 DHCR7

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei26 – 46HelicalSequence analysisAdd BLAST21
Transmembranei58 – 75HelicalSequence analysisAdd BLAST18
Transmembranei91 – 107HelicalSequence analysisAdd BLAST17

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000172893

PTM / Processingi

Proteomic databases

PeptideAtlasiH0YEJ5
PRIDEiH0YEJ5

Expressioni

Gene expression databases

BgeeiENSG00000172893
ExpressionAtlasiH0YEJ5 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0YEJ5
SMRiH0YEJ5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1435 Eukaryota
ENOG410XP67 LUCA
GeneTreeiENSGT00390000000417

Family and domain databases

InterProiView protein in InterPro
IPR001171 Ergosterol_biosynth_ERG4_ERG24
IPR018083 Sterol_reductase_CS
PfamiView protein in Pfam
PF01222 ERG4_ERG24, 1 hit
PROSITEiView protein in PROSITE
PS01017 STEROL_REDUCT_1, 1 hit

Sequencei

Sequence statusi: Fragment.

H0YEJ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
TGNFFYNYMM GIEFNPRIGK WFDFKLFFNG RPGIVAWTLI NLSFAAKQRE
60 70 80 90 100
LHSHVTNAMV LVNVLQAIYV IDFFWNETWY LKTIDICHDH FGWYLGWGDC
110 120 130 140 150
VWLPYLYTLQ KRTRRQGVCQ RQSWGLTPGR WAPEPTLLSS PWAKHRLTPS
160 170 180 190 200
PSPPRVCTWC TTPCSCPPRT PWASCCWAWW ATTSSGWPTT RRTCSAARMG
210 220 230 240
AASSGAGSPR SSSAPTHPPM GRGTTASCWC RASGAWPATS TTSAT
Length:245
Mass (Da):27,644
Last modified:February 22, 2012 - v1
Checksum:i9C99C1D658E396C5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP002387 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000525137; ENSP00000435956; ENSG00000172893
UCSCiuc058euk.1 human

Similar proteinsi

Entry informationi

Entry nameiH0YEJ5_HUMAN
AccessioniPrimary (citable) accession number: H0YEJ5
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: May 23, 2018
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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