ID   H0YBY2_HUMAN            Unreviewed;       149 AA.
AC   H0YBY2;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   27-MAR-2024, entry version 77.
DE   SubName: Full=Macrophage scavenger receptor 1 {ECO:0000313|Ensembl:ENSP00000430536.1};
DE   Flags: Fragment;
GN   Name=MSR1 {ECO:0000313|Ensembl:ENSP00000430536.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000430536.1, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000430536.1, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16421571; DOI=10.1038/nature04406;
RA   Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S., Garber M.,
RA   Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A., Chang J.L.,
RA   Cuomo C.A., Dewar K., FitzGerald M.G., Yang X., Allen N.R., Anderson S.,
RA   Asakawa T., Blechschmidt K., Bloom T., Borowsky M.L., Butler J., Cook A.,
RA   Corum B., DeArellano K., DeCaprio D., Dooley K.T., Dorris L. III,
RA   Engels R., Glockner G., Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K.,
RA   Jaffe D.B., Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P.,
RA   Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H.,
RA   Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C., O'Leary S.B.,
RA   O'Neill K., Parker S.C., Polley A., Raymond C.K., Reichwald K.,
RA   Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R., Smith C.L.,
RA   Sneddon T.P., Talamas J.A., Tenzin P., Topham K., Venkataraman V., Wen G.,
RA   Yamazaki S., Young S.K., Zeng Q., Zimmer A.R., Rosenthal A., Birren B.W.,
RA   Platzer M., Shimizu N., Lander E.S.;
RT   "DNA sequence and analysis of human chromosome 8.";
RL   Nature 439:331-335(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000430536.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AC010785; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC023396; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC087360; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC091162; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC145059; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; H0YBY2; -.
DR   SMR; H0YBY2; -.
DR   MassIVE; H0YBY2; -.
DR   PeptideAtlas; H0YBY2; -.
DR   ProteomicsDB; 36878; -.
DR   Antibodypedia; 601; 1059 antibodies from 39 providers.
DR   Ensembl; ENST00000522672.5; ENSP00000430536.1; ENSG00000038945.15.
DR   UCSC; uc064klu.1; human.
DR   HGNC; HGNC:7376; MSR1.
DR   VEuPathDB; HostDB:ENSG00000038945; -.
DR   GeneTree; ENSGT00950000183074; -.
DR   HOGENOM; CLU_1916319_0_0_1; -.
DR   ChiTaRS; MSR1; human.
DR   Proteomes; UP000005640; Chromosome 8.
DR   Bgee; ENSG00000038945; Expressed in right lung and 129 other cell types or tissues.
DR   ExpressionAtlas; H0YBY2; baseline and differential.
DR   GO; GO:0005581; C:collagen trimer; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; IEA:InterPro.
DR   InterPro; IPR008160; Collagen.
DR   InterPro; IPR003543; SR-AI/II.
DR   PANTHER; PTHR37456:SF5; -; 1.
DR   PANTHER; PTHR37456; SI:CH211-266K2.1; 1.
DR   Pfam; PF01391; Collagen; 1.
DR   PRINTS; PR01408; MACSCAVRCPTR.
PE   1: Evidence at protein level;
KW   Proteomics identification {ECO:0007829|MaxQB:H0YBY2,
KW   ECO:0007829|PeptideAtlas:H0YBY2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT   REGION          57..149
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        125..149
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|Ensembl:ENSP00000430536.1"
SQ   SEQUENCE   149 AA;  15920 MW;  4F4E610ABAE2BAE2 CRC64;
     EISKLEERVY NVSAEIMAMK EEQVHLEQEI KGEVKVLNNI TNDLRLKDWE HSQTLRNITL
     IQGPPGPPGE KGDRGPTGES GPRGFPGPIG PPGLKGDRGA IGFPGSRGLP GYAGRPGNSG
     PKGQKGEKGS GNTLKSRNLT TRKVFAISK
//