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Protein
Submitted name:

Thyroglobulin

Gene

TG

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Protein family/group databases

ESTHERihuman-TG. Thyroglobulin.

Names & Taxonomyi

Protein namesi
Submitted name:
ThyroglobulinImported
Gene namesi
Name:TGImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

EuPathDBiHostDB:ENSG00000042832.11.
HGNCiHGNC:11764. TG.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000042832.

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PaxDbiH0YBY1.
PeptideAtlasiH0YBY1.
PRIDEiH0YBY1.

Expressioni

Gene expression databases

BgeeiENSG00000042832.
ExpressionAtlasiH0YBY1. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliH0YBY1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 85Thyroglobulin type-1InterPro annotationAdd BLAST55

Phylogenomic databases

eggNOGiENOG410IG6K. Eukaryota.
COG2272. LUCA.
GeneTreeiENSGT00680000100015.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
4.10.800.10. 1 hit.
InterProiView protein in InterPro
IPR029058. AB_hydrolase.
IPR002018. CarbesteraseB.
IPR019819. Carboxylesterase_B_CS.
IPR000716. Thyroglobulin_1.
IPR036857. Thyroglobulin_1_sf.
PfamiView protein in Pfam
PF00135. COesterase. 1 hit.
SMARTiView protein in SMART
SM00211. TY. 1 hit.
SUPFAMiSSF53474. SSF53474. 1 hit.
SSF57610. SSF57610. 1 hit.
PROSITEiView protein in PROSITE
PS00941. CARBOXYLESTERASE_B_2. 1 hit.
PS51162. THYROGLOBULIN_1_2. 1 hit.

Sequencei

Sequence statusi: Fragment.

H0YBY1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
XQEQAGSLAC VPCPVGRTTI SAGAFSQTHC VTDCQRNEAG LQCDQNGQYR
60 70 80 90 100
ASQKDRGSGK AFCVDGEGRR LPWWETEAPL EDSQCLMMQK FEKVPESKVI
110 120 130 140 150
FDANAPVAVR SKVPDSEFPV MQCLTDCTED EACSFFTVST TEPEISCDFY
160 170 180 190 200
AWTSDNVACM TSDQKRDALG NSKATSFGSL RCQVKVRSHG QDSPAVYLKK
210 220 230 240 250
GAIICGLLSS PSVLLCNVKD WMDPSEAWAN ATCPGVTYDQ ESHQVILRLG
260 270 280 290 300
DQEFIKSLTP LEGTQDTFTN FQQVYLWKDS DMGSRPESMG CRKDTVPRPA
310 320 330 340 350
SPTEAGLTTE LFSPVDLNQV IVNGNQSLSS QKHWLFKHLF SAQQANLWCL
360 370 380 390 400
SRCVQEHSFC QLAEITESAS LYFTCTLYPE AQVCDDIMES NAQGCRLILP
410 420 430 440 450
QMPKALFRKK VILEDKVKNF YTRLPFQKLM GISIRNKVPM SEKSISNGFF
460 470 480 490 500
ECERRCDADP CCTGFGFLNV SQLKGGEVTC LTLNSLGIQM CSEENGGAWR
510 520 530 540 550
ILDCGSPDIE VHTYPFGWYQ KPIAQNNAPS FCPLVVLPSL TEKVSLDSWQ
560 570 580 590 600
SLALSSVVVD PSIRHFDVAH VSTAATSNFS AVRDLCLSEC SQHEACLITT
610 620 630 640 650
LQTQPGAVRC MFYADTQSCT HSLQGQNCRL LLREEATHIY RKPGISLLSY
660 670 680 690 700
EASVPSVPIS THGRLLGRSQ AIQVGTSWKQ VDQFLGVPYA APPLAERRFQ
710 720 730 740 750
APEPLNWTGS WDASKPRASC WQPGTRTSTS PGVSEDCLYL NVFIPQNVAP
760 770 780 790 800
NASVLVFFHN TMDREESEGW PAIDGSFLAA VGNLIVVTAS YRVGVFGFLS
810 820 830 840 850
SGSGEVSGNW GLLDQVAALT WVQTHIRGFG GDPRRVSLAA DRGGADVASI
860 870 880 890 900
HLLTARATNS QLFRRAVLMG GSALSPAAVI SHERAQQQAI ALAKEVSCPM
910 920 930 940 950
SSSQEVVSCL RQKPANVLND AQTKLLAVSG PFHYWGPVID GHFLREPPAR
960 970 980 990 1000
ALKRSLWVEV DLLIGSSQDD GLINRAKAVK QFEESRGRTS SKTAFYQALQ
1010 1020 1030 1040 1050
NSLGGEDSDA RVEAAATWYY SLEHSTDDYA SFSRALENAT RDYFIICPII
1060 1070 1080 1090 1100
DMASAWAKRA RGNVFMYHAP ENYGHGSLEL LADVQFALGL PFYPAYEGQF
1110 1120 1130 1140 1150
SLEEKSLSLK IMQYFSHFIR SGNPNYPYEF SRKVPTFATP WPDFVPRAGG
1160 1170 1180 1190 1200
ENYKEFSELL PNRQGLKKAD CSFWSKYISS LKTSADGAKG GQSAESEEEE
1210 1220
LTAGSGLRED LLSLQEPGSK TYSK
Length:1,224
Mass (Da):134,741
Last modified:February 22, 2012 - v1
Checksum:iF4B293ACF020D0B4
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF230666 Genomic DNA. No translation available.
AF230667 Genomic DNA. No translation available.
AF235100 Genomic DNA. No translation available.
AF305872 Genomic DNA. No translation available.
KF458854 Genomic DNA. No translation available.
KF495732 Genomic DNA. No translation available.
KF511066 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000519178; ENSP00000430523; ENSG00000042832.
UCSCiuc064qjm.1. human.

Similar proteinsi

Entry informationi

Entry nameiH0YBY1_HUMAN
AccessioniPrimary (citable) accession number: H0YBY1
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: October 25, 2017
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported