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Protein
Submitted name:

E3 ubiquitin-protein ligase RNF4

Gene

RNF4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
E3 ubiquitin-protein ligase RNF4Imported
Gene namesi
Name:RNF4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

HGNCiHGNC:10067. RNF4.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000063978.

PTM / Processingi

Proteomic databases

MaxQBiH0YAI5.
PaxDbiH0YAI5.
PeptideAtlasiH0YAI5.

Expressioni

Gene expression databases

ExpressionAtlasiH0YAI5. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliH0YAI5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini48 – 93RING-typeInterPro annotationAdd BLAST46

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0320. Eukaryota.
ENOG410XV78. LUCA.
GeneTreeiENSGT00390000010318.

Family and domain databases

CDDicd00162. RING. 1 hit.
Gene3Di3.30.40.10. 1 hit.
InterProiView protein in InterPro
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
IPR017907. Znf_RING_CS.
PfamiView protein in Pfam
PF13639. zf-RING_2. 1 hit.
SMARTiView protein in SMART
SM00184. RING. 1 hit.
PROSITEiView protein in PROSITE
PS00518. ZF_RING_1. 1 hit.
PS50089. ZF_RING_2. 1 hit.

Sequencei

Sequence statusi: Fragment.

H0YAI5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
XDHADSCVVS SDDEELSRDR DVYVTTHTPR NARDEGATGL RPSGTVSCPI
60 70 80 90 100
CMDGYSEIVQ NGRLIVSTEC GHVFCSQCLR DSLKNANTCP TCRKKINHKR

LLLVLA
Length:106
Mass (Da):11,663
Last modified:February 22, 2012 - v1
Checksum:i534554BD47146B7C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL110117 Genomic DNA. No translation available.
AL645924 Genomic DNA. No translation available.
BX322586 Genomic DNA. No translation available.
CR450722 Genomic DNA. No translation available.
CR545473 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000508235; ENSP00000427212; ENSG00000063978.
UCSCiuc062uqg.1. human.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiH0YAI5_HUMAN
AccessioniPrimary (citable) accession number: H0YAI5
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: July 5, 2017
This is version 31 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported