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Protein
Submitted name:

Glutamate--cysteine ligase catalytic subunit

Gene

GCLC

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Glutamate--cysteine ligase catalytic subunitImported
Gene namesi
Name:GCLCImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiHostDB:ENSG00000001084.10.
HGNCiHGNC:4311. GCLC.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000001084.

PTM / Processingi

Proteomic databases

MaxQBiH0Y9I7.
PeptideAtlasiH0Y9I7.
PRIDEiH0Y9I7.

Expressioni

Gene expression databases

BgeeiENSG00000001084.
ExpressionAtlasiH0Y9I7. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliH0Y9I7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000011908.

Family and domain databases

InterProiView protein in InterPro
IPR004308. GCS.
IPR014746. Gln_synth/guanido_kin_cat_dom.
PANTHERiPTHR11164. PTHR11164. 2 hits.
SUPFAMiSSF55931. SSF55931. 1 hit.

Sequencei

Sequence statusi: Fragment.

H0Y9I7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
XETKRHADHV RRHGILQFLH IYHAVKDRHK DVLKWGDEVE YMLVSFDHEN
60 70 80 90 100
KKVRLVLSGE KVLETLQEKG ERTNPNHPTL WRPEYGSYMI EGTPGQPYGG
110 120 130 140 150
TMSEFNTVEA NMRKRRKEAT SILEENQALC TITSFPSTLT RNIRHRRGEK
160 170
VVINVPIFKD KNTPSPFIET FTE
Length:173
Mass (Da):20,196
Last modified:February 22, 2012 - v1
Checksum:i2C18AC34BE3F5BAE
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei173Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL033397 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000513939; ENSP00000424211; ENSG00000001084.
UCSCiuc063pcd.1. human.

Similar proteinsi

Entry informationi

Entry nameiH0Y9I7_HUMAN
AccessioniPrimary (citable) accession number: H0Y9I7
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: October 25, 2017
This is version 29 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported