Ankyrin-2

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processⁱ

• signal transduction Source: InterPro

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechⁱ

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingⁱ

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressionⁱ

Gene expression databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structureⁱ

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Fragment.

        10         20         30         40         50
XNVALSSSPI HSGFLVSFMV DARGGAMRGC RHNGLRIIIP PRKCTAPTRV 
        60         70         80         90        100
TCRLVKRHRL ATMPPMVEGE GLASRLIEVG PSGAQFLGPV IVEIPHFAAL 
       110        120        130        140        150
RGKERELVVL RSENGDSWKE HFCDYTEDEL NEILNGMDEV LDSPEDLEKK 
       160        170        180        190        200
RICRIITRDF PQYFAVVSRI KQDSNLIGPE GGVLSSTVVP QVQAVFPEGA 
       210        220        230        240        250
LTKRIRVGLQ AQPMHSELVK KILGNKATFS PIVTLEPRRR KFHKPITMTI 
       260        270        280        290        300
PVPKASSDVM LNGFGGDAPT LRLLCSITGG TTPAQWEDIT GTTPLTFVNE 
       310        320        330        340        350
CVSFTTNVSA RFWLIDCRQI QESVTFASQV YREIICVPYM AKFVVFAKSH 
       360        370        380        390        400
DPIEARLRCF CMTDDKVDKT LEQQENFAEV ARSRDVEVLE GKPIYVDCFG 
       410        420        430        440        450
NLVPLTKSGQ HHIFSFFAFK ENRLPLFVKV RDTTQEPCGR LSFMKEPKST 
       460        470        480        490        500
RGLVHQAICN LNITLPIYTK IDMTSEKNPQ DEQERIEERL AYIADHLGFS 
       510        520        530        540        550
WTELARELDF TEEQIHQIRI ENPNSLQDQS HALLKYWLER DGKHATDTNL 
       560        570        580        590        600
VECLTKINRM DIVHLMETNT EPLQERISHS YAEIEQTITL DHSEGFSVLQ 
       610        620        630        640        650
EELCTAQHKQ KEEQAVSKES ETCDHPPIVS EEDISVGYST FQDGVPKTEG 
       660        670        680        690        700
DSSATALFPQ THKEQVQQDF SGKMQDLPEE SSLEYQQEYF VTTPGTETSE 
       710        720        730        740        750
TQKAMIVPSS PSKTPEEVST PAEEEKLYLQ TPTSSERGGS PIIQEPEEPS 
       760        770        780        790        800
EHREESSPRK TSLVIVESAD NQPETCERLD EDAAFEKELT EELGELEASS 
       810        820        830        840        850
DEEAMVTTRV VRRRVIIQGD DMPEIPPETV TEEEYIDEHG HTVVKKVTRK 
       860        870        880        890        900
IIRRYVSSEG TEKEEIMVQG MPQEPVNIEE GDGYSKVIKR VVLKSDTEQS 
       910        920        930        940        950
EVTLCEPSIL SSTSQFQAEP VEGRRVSKVV KTTVVLGERM EKHLGDSSLA 
       960 
TDLPSAKDDF EEDNNE                                      

Experimental Info

Sequence databases

Genome annotation databases

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 90% Identity
• 50% Identity

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termⁱ