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Protein
Submitted name:

Ankyrin-2

Gene

ANK2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Ankyrin-2Imported
Gene namesi
Name:ANK2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

HGNCiHGNC:493. ANK2.

PTM / Processingi

Proteomic databases

EPDiH0Y931.
MaxQBiH0Y931.

Expressioni

Gene expression databases

ExpressionAtlasiH0Y931. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliH0Y931.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini12 – 119108ZU5InterPro annotationAdd
BLAST
Domaini486 – 57085DeathInterPro annotationAdd
BLAST

Phylogenomic databases

GeneTreeiENSGT00840000129677.

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
InterProiIPR030301. Ankyrin-B.
IPR011029. DEATH-like_dom.
IPR000488. Death_domain.
IPR000906. ZU5_dom.
[Graphical view]
PANTHERiPTHR24123:SF17. PTHR24123:SF17. 1 hit.
PfamiPF00531. Death. 1 hit.
PF00791. ZU5. 2 hits.
[Graphical view]
SMARTiSM00005. DEATH. 1 hit.
SM00218. ZU5. 1 hit.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiPS50017. DEATH_DOMAIN. 1 hit.
PS51145. ZU5. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

H0Y931-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
XNVALSSSPI HSGFLVSFMV DARGGAMRGC RHNGLRIIIP PRKCTAPTRV
60 70 80 90 100
TCRLVKRHRL ATMPPMVEGE GLASRLIEVG PSGAQFLGPV IVEIPHFAAL
110 120 130 140 150
RGKERELVVL RSENGDSWKE HFCDYTEDEL NEILNGMDEV LDSPEDLEKK
160 170 180 190 200
RICRIITRDF PQYFAVVSRI KQDSNLIGPE GGVLSSTVVP QVQAVFPEGA
210 220 230 240 250
LTKRIRVGLQ AQPMHSELVK KILGNKATFS PIVTLEPRRR KFHKPITMTI
260 270 280 290 300
PVPKASSDVM LNGFGGDAPT LRLLCSITGG TTPAQWEDIT GTTPLTFVNE
310 320 330 340 350
CVSFTTNVSA RFWLIDCRQI QESVTFASQV YREIICVPYM AKFVVFAKSH
360 370 380 390 400
DPIEARLRCF CMTDDKVDKT LEQQENFAEV ARSRDVEVLE GKPIYVDCFG
410 420 430 440 450
NLVPLTKSGQ HHIFSFFAFK ENRLPLFVKV RDTTQEPCGR LSFMKEPKST
460 470 480 490 500
RGLVHQAICN LNITLPIYTK IDMTSEKNPQ DEQERIEERL AYIADHLGFS
510 520 530 540 550
WTELARELDF TEEQIHQIRI ENPNSLQDQS HALLKYWLER DGKHATDTNL
560 570 580 590 600
VECLTKINRM DIVHLMETNT EPLQERISHS YAEIEQTITL DHSEGFSVLQ
610 620 630 640 650
EELCTAQHKQ KEEQAVSKES ETCDHPPIVS EEDISVGYST FQDGVPKTEG
660 670 680 690 700
DSSATALFPQ THKEQVQQDF SGKMQDLPEE SSLEYQQEYF VTTPGTETSE
710 720 730 740 750
TQKAMIVPSS PSKTPEEVST PAEEEKLYLQ TPTSSERGGS PIIQEPEEPS
760 770 780 790 800
EHREESSPRK TSLVIVESAD NQPETCERLD EDAAFEKELT EELGELEASS
810 820 830 840 850
DEEAMVTTRV VRRRVIIQGD DMPEIPPETV TEEEYIDEHG HTVVKKVTRK
860 870 880 890 900
IIRRYVSSEG TEKEEIMVQG MPQEPVNIEE GDGYSKVIKR VVLKSDTEQS
910 920 930 940 950
EVTLCEPSIL SSTSQFQAEP VEGRRVSKVV KTTVVLGERM EKHLGDSSLA
960
TDLPSAKDDF EEDNNE
Length:966
Mass (Da):108,728
Last modified:February 22, 2012 - v1
Checksum:i661F6E2132935F46
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004057 Genomic DNA. No translation available.
AC017007 Genomic DNA. No translation available.
AC093617 Genomic DNA. No translation available.
AC093879 Genomic DNA. No translation available.
AC093900 Genomic DNA. No translation available.
AC108042 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000514960; ENSP00000422853; ENSG00000145362.
UCSCiuc062zdl.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004057 Genomic DNA. No translation available.
AC017007 Genomic DNA. No translation available.
AC093617 Genomic DNA. No translation available.
AC093879 Genomic DNA. No translation available.
AC093900 Genomic DNA. No translation available.
AC108042 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliH0Y931.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiH0Y931.
MaxQBiH0Y931.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000514960; ENSP00000422853; ENSG00000145362.
UCSCiuc062zdl.1. human.

Organism-specific databases

HGNCiHGNC:493. ANK2.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00840000129677.

Miscellaneous databases

ChiTaRSiANK2. human.
NextBioi35520578.

Gene expression databases

ExpressionAtlasiH0Y931. baseline and differential.

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
InterProiIPR030301. Ankyrin-B.
IPR011029. DEATH-like_dom.
IPR000488. Death_domain.
IPR000906. ZU5_dom.
[Graphical view]
PANTHERiPTHR24123:SF17. PTHR24123:SF17. 1 hit.
PfamiPF00531. Death. 1 hit.
PF00791. ZU5. 2 hits.
[Graphical view]
SMARTiSM00005. DEATH. 1 hit.
SM00218. ZU5. 1 hit.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiPS50017. DEATH_DOMAIN. 1 hit.
PS51145. ZU5. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. Ensembl
    Submitted (JAN-2012) to UniProtKB
    Cited for: IDENTIFICATION.
  5. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
    Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.
    J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiH0Y931_HUMAN
AccessioniPrimary (citable) accession number: H0Y931
Entry historyi
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: May 11, 2016
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.