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UniProtKB - H0Y931 (H0Y931_HUMAN)

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Protein
Submitted name:

Ankyrin-2

Gene

ANK2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Ankyrin-2Imported
Gene namesi
Name:ANK2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

HGNCiHGNC:493. ANK2.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000145362.

PTM / Processingi

Proteomic databases

MaxQBiH0Y931.
PeptideAtlasiH0Y931.
PRIDEiH0Y931.

Expressioni

Gene expression databases

ExpressionAtlasiH0Y931. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliH0Y931.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 119ZU5InterPro annotationAdd BLAST108
Domaini486 – 570DeathInterPro annotationAdd BLAST85

Phylogenomic databases

GeneTreeiENSGT00840000129677.

Family and domain databases

InterProiView protein in InterPro
IPR030301. Ankyrin-B.
IPR011029. DEATH-like_dom.
IPR000488. Death_domain.
IPR000906. ZU5_dom.
PANTHERiPTHR24123:SF34. PTHR24123:SF34. 1 hit.
PfamiView protein in Pfam
PF00531. Death. 1 hit.
PF00791. ZU5. 2 hits.
SMARTiView protein in SMART
SM00005. DEATH. 1 hit.
SM00218. ZU5. 1 hit.
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiView protein in PROSITE
PS50017. DEATH_DOMAIN. 1 hit.
PS51145. ZU5. 1 hit.

Sequencei

Sequence statusi: Fragment.

H0Y931-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
XNVALSSSPI HSGFLVSFMV DARGGAMRGC RHNGLRIIIP PRKCTAPTRV 
        60         70         80         90        100
TCRLVKRHRL ATMPPMVEGE GLASRLIEVG PSGAQFLGPV IVEIPHFAAL 
       110        120        130        140        150
RGKERELVVL RSENGDSWKE HFCDYTEDEL NEILNGMDEV LDSPEDLEKK 
       160        170        180        190        200
RICRIITRDF PQYFAVVSRI KQDSNLIGPE GGVLSSTVVP QVQAVFPEGA 
       210        220        230        240        250
LTKRIRVGLQ AQPMHSELVK KILGNKATFS PIVTLEPRRR KFHKPITMTI 
       260        270        280        290        300
PVPKASSDVM LNGFGGDAPT LRLLCSITGG TTPAQWEDIT GTTPLTFVNE 
       310        320        330        340        350
CVSFTTNVSA RFWLIDCRQI QESVTFASQV YREIICVPYM AKFVVFAKSH 
       360        370        380        390        400
DPIEARLRCF CMTDDKVDKT LEQQENFAEV ARSRDVEVLE GKPIYVDCFG 
       410        420        430        440        450
NLVPLTKSGQ HHIFSFFAFK ENRLPLFVKV RDTTQEPCGR LSFMKEPKST 
       460        470        480        490        500
RGLVHQAICN LNITLPIYTK IDMTSEKNPQ DEQERIEERL AYIADHLGFS 
       510        520        530        540        550
WTELARELDF TEEQIHQIRI ENPNSLQDQS HALLKYWLER DGKHATDTNL 
       560        570        580        590        600
VECLTKINRM DIVHLMETNT EPLQERISHS YAEIEQTITL DHSEGFSVLQ 
       610        620        630        640        650
EELCTAQHKQ KEEQAVSKES ETCDHPPIVS EEDISVGYST FQDGVPKTEG 
       660        670        680        690        700
DSSATALFPQ THKEQVQQDF SGKMQDLPEE SSLEYQQEYF VTTPGTETSE 
       710        720        730        740        750
TQKAMIVPSS PSKTPEEVST PAEEEKLYLQ TPTSSERGGS PIIQEPEEPS 
       760        770        780        790        800
EHREESSPRK TSLVIVESAD NQPETCERLD EDAAFEKELT EELGELEASS 
       810        820        830        840        850
DEEAMVTTRV VRRRVIIQGD DMPEIPPETV TEEEYIDEHG HTVVKKVTRK 
       860        870        880        890        900
IIRRYVSSEG TEKEEIMVQG MPQEPVNIEE GDGYSKVIKR VVLKSDTEQS 
       910        920        930        940        950
EVTLCEPSIL SSTSQFQAEP VEGRRVSKVV KTTVVLGERM EKHLGDSSLA 
       960 
TDLPSAKDDF EEDNNE
Length:966
Mass (Da):108,728
Last modified:February 22, 2012 - v1
Checksum:i661F6E2132935F46
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004057 Genomic DNA. No translation available.
AC017007 Genomic DNA. No translation available.
AC093617 Genomic DNA. No translation available.
AC093879 Genomic DNA. No translation available.
AC093900 Genomic DNA. No translation available.
AC108042 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000514960; ENSP00000422853; ENSG00000145362.
UCSCiuc062zdl.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004057 Genomic DNA. No translation available.
AC017007 Genomic DNA. No translation available.
AC093617 Genomic DNA. No translation available.
AC093879 Genomic DNA. No translation available.
AC093900 Genomic DNA. No translation available.
AC108042 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliH0Y931.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiH0Y931.
PeptideAtlasiH0Y931.
PRIDEiH0Y931.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000514960; ENSP00000422853; ENSG00000145362.
UCSCiuc062zdl.1. human.

Organism-specific databases

HGNCiHGNC:493. ANK2.
OpenTargetsiENSG00000145362.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00840000129677.

Miscellaneous databases

ChiTaRSiANK2. human.

Gene expression databases

ExpressionAtlasiH0Y931. baseline and differential.

Family and domain databases

InterProiView protein in InterPro
IPR030301. Ankyrin-B.
IPR011029. DEATH-like_dom.
IPR000488. Death_domain.
IPR000906. ZU5_dom.
PANTHERiPTHR24123:SF34. PTHR24123:SF34. 1 hit.
PfamiView protein in Pfam
PF00531. Death. 1 hit.
PF00791. ZU5. 2 hits.
SMARTiView protein in SMART
SM00005. DEATH. 1 hit.
SM00218. ZU5. 1 hit.
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiView protein in PROSITE
PS50017. DEATH_DOMAIN. 1 hit.
PS51145. ZU5. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiH0Y931_HUMAN
AccessioniPrimary (citable) accession number: H0Y931
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: June 7, 2017
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.