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Protein
Submitted name:

Ankyrin-2

Gene

ANK2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Ankyrin-2Imported
Gene namesi
Name:ANK2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

HGNCiHGNC:493. ANK2.

PTM / Processingi

Proteomic databases

PaxDbiH0Y8Y2.
PeptideAtlasiH0Y8Y2.

Expressioni

Gene expression databases

BgeeiENSG00000145362.
ExpressionAtlasiH0Y8Y2. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000349588.

Structurei

3D structure databases

ProteinModelPortaliH0Y8Y2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini579 – 66385DeathInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG4177. Eukaryota.
COG0666. LUCA.
GeneTreeiENSGT00840000129677.

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
InterProiIPR030301. Ankyrin-B.
IPR011029. DEATH-like_dom.
IPR000488. Death_domain.
[Graphical view]
PANTHERiPTHR24123:SF17. PTHR24123:SF17. 1 hit.
PfamiPF00531. Death. 1 hit.
[Graphical view]
SMARTiSM00005. DEATH. 1 hit.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiPS50017. DEATH_DOMAIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

H0Y8Y2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
QDIKMESQQE STLWEMQSDS VSSSFEPTMS ATTTVVGEQI SKVIITKTDV
60 70 80 90 100
DSDSWSEIRE DDEAFEARVK EEEQKIFGLM VDRQSQGTTP DTTPARTPTE
110 120 130 140 150
EGTPTSEQNP FLFQEGKLFE MTRSGAIDMT KRSYADESFH FFQIGQESRE
160 170 180 190 200
ETLSEDVKEG ATGADPLPLE TSAESLALSE SKETVDDEAD LLPDDVSEEV
210 220 230 240 250
EEIPASDAQL NSQMGISAST ETPTKEAVSV GTKDLPTVQT GDIPPLSGVK
260 270 280 290 300
QISCPDSSEP AVQVQLDFST LTRSVYSDRG DDSPDSSPEE QKSVIEIPTA
310 320 330 340 350
PMENVPFTES KSKIPVRTMP TSTPAPPSAE YESSVSEDFL SSVDEENKAD
360 370 380 390 400
EAKPKSKLPV KVPLQRVEQQ LSDLDTSVQK TVAPQGQDMA SIAPDNRSKS
410 420 430 440 450
ESDASSLDSK TKCPVKTRSY TETETESRER AEELELESEE GATRPKILTS
460 470 480 490 500
RLPVKSRSTT SSCRGGTSPT KESKEHFFDL YRNSIEFFEE ISDEASKLVD
510 520 530 540 550
RLTQSEREQE IVSDDESSSA LEVSVIENLP PVETEHSVPE DIFDTRPIWD
560 570 580 590 600
ESIETLIERI PDENGHDHAE DPQDEQERIE ERLAYIADHL GFSWTELARE
610 620 630 640 650
LDFTEEQIHQ IRIENPNSLQ DQSHALLKYW LERDGKHATD TNLVECLTKI
660 670 680 690 700
NRMDIVHLME TNTEPLQERI SHSYAEIEQT ITLDHSEGFS VLQEELCTAQ
710 720 730 740 750
HKQKEEQAVS KESETCDHPP IVSEEDISVG YSTFQDGVPK TEGDSSATAL
760 770 780 790 800
FPQTHKEQVQ QDFSGKMQDL PEESSLEYQQ EYFVTTPGTE TSETQKAMIV
810 820 830 840 850
PSSPSKTPEE VSTPAEEEKL YLQTPTSSER GGSPIIQEPE EPSEHREESS
860 870 880 890 900
PRKTSLVIVE SADNQPETCE RLDEDAAFEK GDDMPEIPPE TVTEEEYIDE
910 920 930 940 950
HGHTVVKKVT RKIIRRYVSS EGTEKEEIMV QGMPQEPVNI EEGDGYSKVI
960 970 980 990 1000
KRVVLKSDTE QSEVTLCEPS ILSSTSQFQA EPVEGRRVSK VVKTTVVLGE
1010 1020
RMEKHLGDSS LATDLPSAKD DFEEDNNE
Length:1,028
Mass (Da):114,698
Last modified:February 22, 2012 - v1
Checksum:iF7C800CA933E3A6E
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004057 Genomic DNA. No translation available.
AC017007 Genomic DNA. No translation available.
AC093617 Genomic DNA. No translation available.
AC093879 Genomic DNA. No translation available.
AC093900 Genomic DNA. No translation available.
AC108042 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000505342; ENSP00000422498; ENSG00000145362.
UCSCiuc062zdt.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004057 Genomic DNA. No translation available.
AC017007 Genomic DNA. No translation available.
AC093617 Genomic DNA. No translation available.
AC093879 Genomic DNA. No translation available.
AC093900 Genomic DNA. No translation available.
AC108042 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliH0Y8Y2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000349588.

Proteomic databases

PaxDbiH0Y8Y2.
PeptideAtlasiH0Y8Y2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000505342; ENSP00000422498; ENSG00000145362.
UCSCiuc062zdt.1. human.

Organism-specific databases

HGNCiHGNC:493. ANK2.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4177. Eukaryota.
COG0666. LUCA.
GeneTreeiENSGT00840000129677.

Miscellaneous databases

ChiTaRSiANK2. human.

Gene expression databases

BgeeiENSG00000145362.
ExpressionAtlasiH0Y8Y2. baseline and differential.

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
InterProiIPR030301. Ankyrin-B.
IPR011029. DEATH-like_dom.
IPR000488. Death_domain.
[Graphical view]
PANTHERiPTHR24123:SF17. PTHR24123:SF17. 1 hit.
PfamiPF00531. Death. 1 hit.
[Graphical view]
SMARTiSM00005. DEATH. 1 hit.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiPS50017. DEATH_DOMAIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiH0Y8Y2_HUMAN
AccessioniPrimary (citable) accession number: H0Y8Y2
Entry historyi
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: September 7, 2016
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.