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Protein
Submitted name:

Transient receptor potential cation channel subfamily M member 8

Gene

TRPM8

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Transient receptor potential cation channel subfamily M member 8Imported
Gene namesi
Name:TRPM8Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000144481.16
HGNCiHGNC:17961 TRPM8

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei58 – 78HelicalSequence analysisAdd BLAST21
Transmembranei90 – 108HelicalSequence analysisAdd BLAST19
Transmembranei128 – 145HelicalSequence analysisAdd BLAST18
Transmembranei157 – 176HelicalSequence analysisAdd BLAST20
Transmembranei216 – 245HelicalSequence analysisAdd BLAST30
Transmembranei266 – 286HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000144481

PTM / Processingi

Proteomic databases

PRIDEiH0Y7P0

Expressioni

Gene expression databases

BgeeiENSG00000144481
ExpressionAtlasiH0Y7P0 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0Y7P0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini46 – 249Ion_transInterPro annotationAdd BLAST204

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410INBX Eukaryota
ENOG4110YBY LUCA
GeneTreeiENSGT00760000119127

Family and domain databases

InterProiView protein in InterPro
IPR005821 Ion_trans_dom
IPR029603 TRPM8
PANTHERiPTHR13800:SF9 PTHR13800:SF9, 2 hits
PfamiView protein in Pfam
PF00520 Ion_trans, 1 hit

Sequencei

Sequence statusi: Fragment.

H0Y7P0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
TECYSSDEDL AEQLLVYSCE AWGGSNCLEL AVEATDQHFI AQPGVQWYVN
60 70 80 90 100
GVNYFTDLWN VMDTLGLFYF IAGIVFRLHS SNKSSLYSGR VIFCLDYIIF
110 120 130 140 150
TLRLIHIFTV SRNLGPKIIM LQRMLIDVFF FLFLFAVWMV AFGVARQGIL
160 170 180 190 200
RQNEQRWRWI FRSVIYEPYL AMFGQVPSDV DGTTYDFAHC TFTGNESKPL
210 220 230 240 250
CVELDEHNLP RFPEWITIPL VCIYMLSTNI LLVNLLVAMF GYTVGTVQEN
260 270 280 290 300
NDQVWKFQRY FLVQEYCSRL NIPFPFIVFA YFYMVVKKCF KCCCKEKNME
310 320 330 340 350
SSVCCFKNED NETLAWEGVM KENYLVKINT KANDTSEEMR HRFRQLDTKI
360 370
ILRNADEQFC YRLLNERFSD PWVHGG
Length:376
Mass (Da):44,149
Last modified:February 22, 2012 - v1
Checksum:i080B241081061800
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005538 Genomic DNA No translation available.
KF510796 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000456930; ENSP00000414198; ENSG00000144481
UCSCiuc061two.1 human

Similar proteinsi

Entry informationi

Entry nameiH0Y7P0_HUMAN
AccessioniPrimary (citable) accession number: H0Y7P0
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: May 23, 2018
This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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