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Protein
Submitted name:

Breakpoint cluster region protein

Gene

BCR

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Breakpoint cluster region proteinImported
Gene namesi
Name:BCRImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 22

Organism-specific databases

EuPathDBiHostDB:ENSG00000186716.19
HGNCiHGNC:1014 BCR

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000186716

PTM / Processingi

Proteomic databases

MaxQBiH0Y554
PeptideAtlasiH0Y554
PRIDEiH0Y554

Expressioni

Gene expression databases

BgeeiENSG00000186716
ExpressionAtlasiH0Y554 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliH0Y554
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini18 – 175DHInterPro annotationAdd BLAST158

Phylogenomic databases

GeneTreeiENSGT00910000143995

Family and domain databases

CDDicd00160 RhoGEF, 1 hit
Gene3Di1.20.900.10, 2 hits
2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR037769 Abr/Bcr
IPR035899 DBL_dom_sf
IPR000219 DH-domain
IPR001331 GDS_CDC24_CS
IPR011993 PH-like_dom_sf
PANTHERiPTHR23182 PTHR23182, 2 hits
PfamiView protein in Pfam
PF00621 RhoGEF, 2 hits
SMARTiView protein in SMART
SM00325 RhoGEF, 1 hit
SUPFAMiSSF48065 SSF48065, 1 hit
PROSITEiView protein in PROSITE
PS00741 DH_1, 1 hit
PS50010 DH_2, 1 hit

Sequencei

Sequence statusi: Fragment.

H0Y554-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
ALESTKASEL DLEKGLEMRK WVLSGILASE ETYLSHLEAL LLPMKPLKAA
60 70 80 90 100
ATTSQPVLTS QQIETIFFKV PELYEIHKEF YDGLFPRVQQ WSHQQRVGDL
110 120 130 140 150
FQKLNLRARS NKDAKDPTTK NSLETLLYKP VDRVTRSTLV LHDLLKHTPA
160 170 180 190 200
SHPDHPLLQD ALRISQNFLS SINEEITPRR QSMTVKKGEH RQLLKDSFMV
210 220 230 240 250
ELVEGARKLR HVFLFTDLLL CTKLKKQSGG KTQQYDCKWY IPLTDLSFQM

VDELEAV
Length:257
Mass (Da):29,612
Last modified:February 22, 2012 - v1
Checksum:iC4C1F16880B1907F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei257Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KF457370 Genomic DNA No translation available.
KF457372 Genomic DNA No translation available.
KF457379 Genomic DNA No translation available.
KF457382 Genomic DNA No translation available.
U07000 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000427791; ENSP00000396531; ENSG00000186716
UCSCiuc062cew.1 human

Similar proteinsi

Entry informationi

Entry nameiH0Y554_HUMAN
AccessioniPrimary (citable) accession number: H0Y554
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: March 28, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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