Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phospholipid-transporting ATPase

Gene

ATP11A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + H2O + phospholipid(Side 1) = ADP + phosphate + phospholipid(Side 2).UniRule annotationSAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotationSAAS annotation, MagnesiumSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Phospholipid-transporting ATPaseUniRule annotation (EC:3.6.3.1UniRule annotation)
Gene namesi
Name:ATP11AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 13

Organism-specific databases

EuPathDBiHostDB:ENSG00000068650.18.
HGNCiHGNC:13552. ATP11A.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei44 – 62HelicalUniRule annotationAdd BLAST19
Transmembranei270 – 293HelicalUniRule annotationAdd BLAST24
Transmembranei324 – 343HelicalUniRule annotationAdd BLAST20

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000068650.

PTM / Processingi

Proteomic databases

MaxQBiH0Y547.
PaxDbiH0Y547.
PeptideAtlasiH0Y547.
PRIDEiH0Y547.

Expressioni

Gene expression databases

BgeeiENSG00000068650.
ExpressionAtlasiH0Y547. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliH0Y547.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini18 – 71PhoLip_ATPase_NInterPro annotationAdd BLAST54
Domaini826 – 929PhoLip_ATPase_CInterPro annotationAdd BLAST104

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili603 – 627Sequence analysisAdd BLAST25

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0206. Eukaryota.
COG0474. LUCA.
GeneTreeiENSGT00870000136387.

Family and domain databases

Gene3Di3.40.1110.10. 1 hit.
3.40.50.1000. 1 hit.
InterProiView protein in InterPro
IPR030361. ATP11A.
IPR023299. ATPase_P-typ_cyto_dom_N.
IPR018303. ATPase_P-typ_P_site.
IPR023298. ATPase_P-typ_TM_dom_sf.
IPR008250. ATPase_P-typ_transduc_dom_A_sf.
IPR036412. HAD-like_sf.
IPR023214. HAD_sf.
IPR006539. P-type_ATPase_IV.
IPR032631. P-type_ATPase_N.
IPR001757. P_typ_ATPase.
IPR032630. P_typ_ATPase_c.
PANTHERiPTHR24092. PTHR24092. 1 hit.
PTHR24092:SF33. PTHR24092:SF33. 1 hit.
PfamiView protein in Pfam
PF16212. PhoLip_ATPase_C. 1 hit.
PF16209. PhoLip_ATPase_N. 1 hit.
SUPFAMiSSF56784. SSF56784. 3 hits.
SSF81653. SSF81653. 2 hits.
SSF81660. SSF81660. 1 hit.
SSF81665. SSF81665. 3 hits.
TIGRFAMsiTIGR01652. ATPase-Plipid. 1 hit.
TIGR01494. ATPase_P-type. 3 hits.
PROSITEiView protein in PROSITE
PS00154. ATPASE_E1_E2. 1 hit.

Sequencei

Sequence statusi: Fragment.

H0Y547-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
XYVGHREPPP GAEAYIPQRY PDNRIVSSKY TFWNFIPKNL FEQFRRVANF
60 70 80 90 100
YFLIIFLVQL IIDTPTSPVT SGLPLFFVIT VTAIKQGYED WLRHKADNAM
110 120 130 140 150
NQCPVHFIQH GKLVRKQSRK LRVGDIVMVK EDETFPCDLI FLSSNRGDGT
160 170 180 190 200
CHVTTASLDG ESSHKTHYAV QDTKGFHTEE DIGGLHATIE CEQPQPDLYK
210 220 230 240 250
FVGRINVYSD LNDPVVRPLG SENLLLRGAT LKNTEKIFGV AIYTGMETKM
260 270 280 290 300
ALNYQSKSQK RSAVEKSMNA FLIVYLCILI SKALINTVLK YMWQSEPFRD
310 320 330 340 350
EPWYNQKTES ERQRNLFLKA FTDFLAFMVL FNYIIPVSMY VTVEMQKFLG
360 370 380 390 400
SYFITWDEDM FDEETGEGPL VNTSDLNEEL GQVEYIFTDK TGTLTENNME
410 420 430 440 450
FKECCIEGHV YVPHVICNGQ VLPESSGIDM IDSSPSVNGR EREELFFRAL
460 470 480 490 500
CLCHTVQVKD DDSVDGPRKS PDGGKSCVYI SSSPDEVALV EGVQRLGFTY
510 520 530 540 550
LRLKDNYMEI LNRENHIERF ELLEILSFDS VRRRMSVIVK SATGEIYLFC
560 570 580 590 600
KGADSSIFPR VIEGKVDQIR ARVERNAVEG LRTLCVAYKR LIQEEYEGIC
610 620 630 640 650
KLLQAAKVAL QDREKKLAEA YEQIEKDLTL LGATAVEDRL QEKAADTIEA
660 670 680 690 700
LQKAGIKVWV LTGDKMETAA ATCYACKLFR RNTQLLELTT KRIEEQSLHD
710 720 730 740 750
VLFELSKTVL RHSGSLTRDN LSGLSADMQD YGLIIDGAAL SLIMKPREDG
760 770 780 790 800
SSGNYRELFL EICRSCSAVL CCRMAPLQKA QIVKLIKFSK EHPITLAIGD
810 820 830 840 850
GANDVSMILE AHVGIGVIGK EGRQAARNSD YAIPKFKHLK KMLLVHGHFY
860 870 880 890 900
YIRISELVQY FFYKNVCFIF PQFLYQFFCG FSQQTLYDTA YLTLYNISFT
910 920 930
SLPILLYSLM EQHVGIDVLK RDPTLYRYHP PNSLS
Length:935
Mass (Da):106,624
Last modified:February 22, 2012 - v1
Checksum:i9ECE6E67303D01BD
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL139384 Genomic DNA. No translation available.
AL162711 Genomic DNA. No translation available.
AL356740 Genomic DNA. No translation available.
AL356752 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000418678; ENSP00000396374; ENSG00000068650.
UCSCiuc058yjr.1. human.

Similar proteinsi

Entry informationi

Entry nameiH0Y547_HUMAN
AccessioniPrimary (citable) accession number: H0Y547
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: November 22, 2017
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation
The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported