Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

ATP-binding cassette sub-family A member 9

Gene

ABCA9

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi517 – 524ATPPROSITE-ProRule annotation8
Nucleotide bindingi1288 – 1295ATPPROSITE-ProRule annotation8

GO - Molecular functioni

Keywordsi

LigandATP-bindingPROSITE-ProRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-binding cassette sub-family A member 9Imported
Gene namesi
Name:ABCA9Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000154258.16.
HGNCiHGNC:39. ABCA9.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei31 – 48HelicalSequence analysisAdd BLAST18
Transmembranei215 – 241HelicalSequence analysisAdd BLAST27
Transmembranei265 – 287HelicalSequence analysisAdd BLAST23
Transmembranei294 – 323HelicalSequence analysisAdd BLAST30
Transmembranei329 – 350HelicalSequence analysisAdd BLAST22
Transmembranei357 – 378HelicalSequence analysisAdd BLAST22
Transmembranei398 – 420HelicalSequence analysisAdd BLAST23
Transmembranei1026 – 1045HelicalSequence analysisAdd BLAST20
Transmembranei1065 – 1085HelicalSequence analysisAdd BLAST21
Transmembranei1097 – 1116HelicalSequence analysisAdd BLAST20
Transmembranei1123 – 1145HelicalSequence analysisAdd BLAST23
Transmembranei1165 – 1185HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000154258.

PTM / Processingi

Proteomic databases

PeptideAtlasiH0Y4U7.
PRIDEiH0Y4U7.

Expressioni

Gene expression databases

BgeeiENSG00000154258.
ExpressionAtlasiH0Y4U7. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliH0Y4U7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini481 – 716ABC transporterInterPro annotationAdd BLAST236
Domaini1250 – 1483ABC transporterInterPro annotationAdd BLAST234

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0059. Eukaryota.
COG1131. LUCA.
GeneTreeiENSGT00760000118965.

Family and domain databases

InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR026082. ABCA.
IPR027417. P-loop_NTPase.
PANTHERiPTHR19229. PTHR19229. 2 hits.
PfamiView protein in Pfam
PF00005. ABC_tran. 2 hits.
SMARTiView protein in SMART
SM00382. AAA. 2 hits.
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiView protein in PROSITE
PS50893. ABC_TRANSPORTER_2. 2 hits.

Sequencei

Sequence statusi: Complete.

H0Y4U7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKRRMSVGQ QTWALLCKNC LKKWRMKRQT LLEWLFSFLL VLFLYLFFSN
60 70 80 90 100
LHQVHDTPQM SSMDLGRVDS FNDTNYVIAF APESKTTQEI MNKVASAPFL
110 120 130 140 150
KGRTIMGWPD EKSMDELDLN YSIDAVRVIF TDTFSYHLKF SWGHRIPMMK
160 170 180 190 200
EHRDHSAHCQ AVNEKMKCEG SEFWEKGFVA FQAAINAAII EIATNHSVME
210 220 230 240 250
QLMSVTGVHM KILPFVAQGG VATDFFIFFC IISFSTFIYY VSVNVTQERQ
260 270 280 290 300
YITSLMTMMG LRESAFWLSW GLMYAGFILI MATLMALIVK SAQIVVLTGF
310 320 330 340 350
VMVFTLFLLY GLSLITLAFL MSVLIKKPFL TGLVVFLLIV FWGILGFPAL
360 370 380 390 400
YTRLPAFLEW TLCLLSPFAF TVGMAQLIHL DYDVNSNAHL DSSQNPYLII
410 420 430 440 450
ATLFMLVFDT LLYLVLTLYF DKILPAEYGH RCSPLFFLKS CFWFQHGRAN
460 470 480 490 500
HVVLENETDS DPTPNDCFEP VSPEFCGKEA IRIKNLKKEY AGKCERVEAL
510 520 530 540 550
KGVVFDIYEG QITALLGHSG AGKTTLLNIL SGLSVPTSGS VTVYNHTLSR
560 570 580 590 600
MADIENISKF TGFCPQSNVQ FGFLTVKENL RLFAKIKGIL PHEVEKEVQR
610 620 630 640 650
VVQELEMENI QDILAQNLSG GQNRKLTFGI AILGDPQVLL LDEPTAGLDP
660 670 680 690 700
LSRHRIWNLL KEGKSDRVIL FSTQFIDEAD ILADRKVFIS NGKLKCAGSS
710 720 730 740 750
LFLKKKWGIG YHLSLHLNER CDPESITSLV KQHISDAKLT AQSEEKLVYI
760 770 780 790 800
LPLERTNKFP ELYRDLDRCS NQGIEDYGVS ITTLNEVFLK LEGKSTIDES
810 820 830 840 850
DIGIWGQLQT DGAKDIGSLV ELEQVLSSFH ETRKTISGVA LWRQQVCAIA
860 870 880 890 900
KVRFLKLKKE RKSLWTILLL FGISFIPQLL EHLFYESYQK SYPWELSPNT
910 920 930 940 950
YFLSPGQQPQ DPLTHLLVIN KTGSTIDNFL HSLRRQNIAI EVDAFGTRNG
960 970 980 990 1000
TDDPSYNGAI IVSGDEKDHR FSIACNTKRL NCFPVLLDVI SNGLLGIFNS
1010 1020 1030 1040 1050
SEHIQTDRST FFEEHMDYEY GYRSNTFFWI PMAASFTPYI AMSSIGDYKK
1060 1070 1080 1090 1100
KAHSQLRISG LYPSAYWFGQ ALVDVSLYFL ILLLMQIMDY IFSPEEIIFI
1110 1120 1130 1140 1150
IQNLLIQVVI FSIVATDLNE YGFLGLFFGT MLIPPFTLIG SLFIFSEISP
1160 1170 1180 1190 1200
DSMDYLGASE SEIVYLALLI PYLHFLIFLF ILRCLEMNCR KKLMRKDPVF
1210 1220 1230 1240 1250
RISPRSNAIF PNPEEPEGEE EDIQMERMRT VNAMAVRDFD ETPVIIASCL
1260 1270 1280 1290 1300
RKEYAGKKKN CFSKRKKKIA TRNVSFCVKK GEVIGLLGHN GAGKSTTIKM
1310 1320 1330 1340 1350
ITGDTKPTAG QVILKGSGGG EPLGFLGYCP QENALWPNLT VRQHLEVYAA
1360 1370 1380 1390 1400
VKGLRKGDAM IAITRLVDAL KLQDQLKAPV KTLSEGIKRK LCFVLSILGN
1410 1420 1430 1440 1450
PSVVLLDEPS TGMDPEGQQQ MWQVIRATFR NTERGALLTT HYMAEAEAVC
1460 1470 1480 1490 1500
DRVAIMVSGR LRCIGSIQHL KSKFGKDYLL EMKLKNLAQM EPLHAEILRL
1510 1520 1530 1540 1550
FPQAAQQERF SSLMVYKLPV EDVRPLSQAF FKLEIVKQSF DLEEYSLSQS
1560 1570 1580
TLEQVFLELS KEQELGDLEE DFDPSVKWKL LLQEEP
Length:1,586
Mass (Da):179,970
Last modified:January 9, 2013 - v2
Checksum:i22C72E2D3603073D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005922 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000453985; ENSP00000394264; ENSG00000154258.
UCSCiuc010dez.4. human.

Similar proteinsi

Entry informationi

Entry nameiH0Y4U7_HUMAN
AccessioniPrimary (citable) accession number: H0Y4U7
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: January 9, 2013
Last modified: January 31, 2018
This is version 44 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported