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Protein
Submitted name:

Myeloid differentiation primary response protein MyD88

Gene

MYD88

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Myeloid differentiation primary response protein MyD88Imported
Gene namesi
Name:MYD88Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000172936.12
HGNCiHGNC:7562 MYD88

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000172936

PTM / Processingi

Proteomic databases

MaxQBiH0Y4G9
PRIDEiH0Y4G9

Expressioni

Gene expression databases

BgeeiENSG00000172936
ExpressionAtlasiH0Y4G9 baseline and differential
GenevisibleiH0Y4G9 HS

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliH0Y4G9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini44 – 121DeathInterPro annotationAdd BLAST78
Domaini171 – 316TIRInterPro annotationAdd BLAST146

Phylogenomic databases

eggNOGiENOG410IIN8 Eukaryota
ENOG410ZIY0 LUCA
GeneTreeiENSGT00510000048324
OMAiRCKRMVV

Family and domain databases

CDDicd08312 Death_MyD88, 1 hit
Gene3Di3.40.50.10140, 1 hit
InterProiView protein in InterPro
IPR011029 DEATH-like_dom_sf
IPR000488 Death_domain
IPR034249 MyD88_Death
IPR017281 Myelin_different_resp_MyD88
IPR000157 TIR_dom
IPR035897 Toll_tir_struct_dom_sf
PANTHERiPTHR15079 PTHR15079, 1 hit
PfamiView protein in Pfam
PF00531 Death, 1 hit
PF01582 TIR, 1 hit
PIRSFiPIRSF037756 MyD88, 1 hit
SMARTiView protein in SMART
SM00005 DEATH, 1 hit
SM00255 TIR, 1 hit
SUPFAMiSSF47986 SSF47986, 1 hit
SSF52200 SSF52200, 1 hit
PROSITEiView protein in PROSITE
PS50017 DEATH_DOMAIN, 1 hit
PS50104 TIR, 1 hit

Sequencei

Sequence statusi: Fragment.

H0Y4G9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
RPDRAEAPGP PAMAAGGPGA GSAAPVSSTS SLPLAALNMR VRRRLSLFLN
60 70 80 90 100
VRTQVAADWT ALAEEMDFEY LEIRQLETQA DPTGRLLDAW QGRPGASVGR
110 120 130 140 150
LLELLTKLGR DDVLLELGPS IEEDCQKYIL KQQQEEAEKP LQVAAVDSSV
160 170 180 190 200
PRTAELAGIT TLDDPLGHMP ERFDAFICYC PSDIQFVQEM IRQLEQTNYR
210 220 230 240 250
LKLCVSDRDV LPGTCVWSIA SELIEKRLAR RPRGGCRRMV VVVSDDYLQS
260 270 280 290 300
KECDFQTKFA LSLSPGAHQK RLIPIKYKAM KKEFPSILRF ITVCDYTNPC
310
TKSWFWTRLA KALSLP
Length:316
Mass (Da):35,313
Last modified:February 22, 2012 - v1
Checksum:i11249F8778C047B1
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006309 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000421516; ENSP00000391753; ENSG00000172936
UCSCiuc062ifw.1 human

Similar proteinsi

Entry informationi

Entry nameiH0Y4G9_HUMAN
AccessioniPrimary (citable) accession number: H0Y4G9
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: May 23, 2018
This is version 46 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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