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Protein
Submitted name:

Prickle-like protein 3

Gene

PRICKLE3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Prickle-like protein 3Imported
Gene namesi
Name:PRICKLE3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000012211.12.
HGNCiHGNC:6645. PRICKLE3.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000012211.

PTM / Processingi

Proteomic databases

MaxQBiH0Y413.
PaxDbiH0Y413.
PeptideAtlasiH0Y413.

Expressioni

Gene expression databases

BgeeiENSG00000012211.
ExpressionAtlasiH0Y413. baseline and differential.

Interactioni

Protein-protein interaction databases

IntActiH0Y413. 2 interactors.

Structurei

3D structure databases

ProteinModelPortaliH0Y413.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 114PETInterPro annotationAdd BLAST109
Domaini116 – 180LIM zinc-bindingInterPro annotationAdd BLAST65
Domaini181 – 241LIM zinc-bindingInterPro annotationAdd BLAST61
Domaini242 – 305LIM zinc-bindingInterPro annotationAdd BLAST64

Keywords - Domaini

LIM domainPROSITE-ProRule annotationSAAS annotation, RepeatSAAS annotation

Phylogenomic databases

eggNOGiKOG1704. Eukaryota.
ENOG410XP0W. LUCA.
GeneTreeiENSGT00550000074438.

Family and domain databases

CDDicd09415. LIM1_Prickle. 1 hit.
cd09418. LIM2_Prickle. 1 hit.
cd09420. LIM3_Prickle. 1 hit.
cd09827. PET_Prickle. 1 hit.
InterProiView protein in InterPro
IPR033725. LIM1_prickle.
IPR033726. LIM2_prickle.
IPR033727. LIM3_prickle.
IPR010442. PET_domain.
IPR033723. PET_prickle.
IPR001781. Znf_LIM.
PfamiView protein in Pfam
PF00412. LIM. 3 hits.
PF06297. PET. 1 hit.
SMARTiView protein in SMART
SM00132. LIM. 3 hits.
PROSITEiView protein in PROSITE
PS00478. LIM_DOMAIN_1. 1 hit.
PS50023. LIM_DOMAIN_2. 3 hits.
PS51303. PET. 1 hit.

Sequencei

Sequence statusi: Complete.

H0Y413-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCRLISDFQR HSISDDDSGC ASEEYAWVPP GLKPEQVYQF FSCLPEDKVP
60 70 80 90 100
YVNSPGEKYR IKQLLHQLPP HDSEAQYCTA LEEEEKKELR AFSQQRKREN
110 120 130 140 150
LGRGIVRIFP VTITGAICEE CGKQIGGGDI AVFASRAGLG ACWHPQCFVC
160 170 180 190 200
TTCQELLVDL IYFYHVGKVY CGRHHAECLR PRCQACDEII FSPECTEAEG
210 220 230 240 250
RHWHMDHFCC FECEASLGGQ RYVMRQSRPH CCACYEARHA EYCDGCGEHI
260 270 280 290 300
GLDQGQMAYE GQHWHASDRC FCCSRCGRAL LGRPFLPRRG LIFCSRACSL
310 320 330 340 350
GSEPTAPGPS RRSWSAGPVT APLAASTASF SAVKGASETT TKGTSTELAP
360 370 380 390 400
ATGPEEPSRF LRGAPHRHSM PELGLRSVPE PPPESPGQPN LRPDDSAFGR
410 420 430 440 450
QSTPRVSFRD PLVSEGGPRR TLSAPPAQRR RPRSPPPRAP SRRRHHHHNH
460 470 480 490 500
HHHHNRHPSR RRHYQCDAGS GSDSESCSSS PSSSSSESSE DDGFFLGERI
510 520 530 540
PLPPHLCRPM PAQDTAMETF NSPSLSLPRD SRAGMPRQAR DKNCIVA
Length:547
Mass (Da):60,792
Last modified:October 29, 2014 - v2
Checksum:i245761350E0C3EF8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC232271 Genomic DNA. No translation available.
RefSeqiNP_001294908.1. NM_001307979.1.
UniGeneiHs.732712.

Genome annotation databases

EnsembliENST00000453382; ENSP00000388599; ENSG00000012211.
GeneIDi4007.
UCSCiuc064zev.1. human.

Similar proteinsi

Entry informationi

Entry nameiH0Y413_HUMAN
AccessioniPrimary (citable) accession number: H0Y413
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: October 29, 2014
Last modified: September 27, 2017
This is version 43 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported