Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Myosin IXA

Gene

MYO9A

Organism
Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi239 – 246ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActin-bindingPROSITE-ProRule annotation, Motor protein, MyosinPROSITE-ProRule annotationSAAS annotation
LigandATP-bindingSAAS annotation, Metal-bindingSAAS annotation, Nucleotide-binding, ZincSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Myosin IXAImported
Gene namesi
Name:MYO9AImported
OrganismiOtolemur garnettii (Small-eared galago) (Garnett's greater bushbaby)Imported
Taxonomic identifieri30611 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesStrepsirrhiniLorisiformesGalagidaeOtolemur
Proteomesi
  • UP000005225 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi30611.ENSOGAP00000005478

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 112Ras-associatingInterPro annotationAdd BLAST99
Domaini146 – 1016Myosin motorInterPro annotationAdd BLAST871
Domaini2070 – 2119Phorbol-ester/DAG-typeInterPro annotationAdd BLAST50
Domaini2134 – 2322Rho-GAPInterPro annotationAdd BLAST189

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni898 – 920Actin-bindingPROSITE-ProRule annotationAdd BLAST23

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1270 – 1290Sequence analysisAdd BLAST21
Coiled coili1482 – 1525Sequence analysisAdd BLAST44
Coiled coili2415 – 2442Sequence analysisAdd BLAST28

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1453 Eukaryota
KOG4229 Eukaryota
COG5022 LUCA
GeneTreeiENSGT00900000140810
InParanoidiH0WTJ1
OMAiSSKYSFQ
OrthoDBiEOG091G003X
TreeFamiTF316834

Family and domain databases

CDDicd00029 C1, 1 hit
cd01385 MYSc_Myo9, 1 hit
Gene3Di1.10.555.101 hit
3.40.850.103 hits
InterProiView protein in InterPro
IPR000048 IQ_motif_EF-hand-BS
IPR036961 Kinesin_motor_dom_sf
IPR028558 MYO9A
IPR001609 Myosin_head_motor_dom
IPR036023 MYSc_Myo9
IPR027417 P-loop_NTPase
IPR002219 PE/DAG-bd
IPR000159 RA_dom
IPR008936 Rho_GTPase_activation_prot
IPR000198 RhoGAP_dom
IPR029071 Ubiquitin-like_domsf
PANTHERiPTHR13140:SF9 PTHR13140:SF9, 1 hit
PfamiView protein in Pfam
PF00612 IQ, 4 hits
PF00063 Myosin_head, 2 hits
PF00788 RA, 1 hit
PF00620 RhoGAP, 1 hit
PRINTSiPR00193 MYOSINHEAVY
SMARTiView protein in SMART
SM00109 C1, 1 hit
SM00015 IQ, 5 hits
SM00242 MYSc, 1 hit
SM00314 RA, 1 hit
SM00324 RhoGAP, 1 hit
SUPFAMiSSF48350 SSF48350, 1 hit
SSF52540 SSF52540, 3 hits
SSF54236 SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS50096 IQ, 4 hits
PS51456 MYOSIN_MOTOR, 1 hit
PS50200 RA, 1 hit
PS50238 RHOGAP, 1 hit
PS00479 ZF_DAG_PE_1, 1 hit
PS50081 ZF_DAG_PE_2, 1 hit

Sequencei

Sequence statusi: Complete.

H0WTJ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNINDGGRRR FEDNEHTLRI YPGTISEGTI YCPIPARKNS TAAEVIDSLI
60 70 80 90 100
NKLHLDKTKC YVLAEVKEFG GEEWILNPTD CPVQRMMLWP RMALENRLSG
110 120 130 140 150
EDYRFLLREK NLDGSIHYGS LQSWLRVTEE RRRMMERGFL PQPQQKDFDD
160 170 180 190 200
LCSLPDLNEK TLLENLRNRF KHEKIYTYVG SILIVINPFK FLPIYNPKYV
210 220 230 240 250
KMYDNHQLGK LEPHIYAVAD VAYHAMLQRK KNQCIVISGE SGSGKTQSTN
260 270 280 290 300
FLIHHLTALS QKGFASGVEQ IILGAGPVLE AFGNAKTAHN NNSSRFGKFI
310 320 330 340 350
QVNYQETGTV LGCFLFSILK AARRRFYQNK KIRNYHVFYY LLAGASEEER
360 370 380 390 400
SAFHLKQPEE YHYLNQITKK PLRQSWDDYY YDSEPDCFTV EGEDLRHDFE
410 420 430 440 450
RLQLAMEMVG FLPKTRRQIF SLLSAILHLG NICYKKKTYR DDSIDICNPE
460 470 480 490 500
VLPIVSELLE VKEEMLFEAL VTRKTVTVGE KLILPYKLAE AVTVRNSMAK
510 520 530 540 550
SLYSALFDWI VFRINHALLN SKDLEHETKT LSIGVLDIFG FEDYENNSFE
560 570 580 590 600
QFCINFANER LQHYFNQHIF KLEQEEYRTE GISWHNIDYI DNTCCINLIS
610 620 630 640 650
KKPTGLLHLL DEESNFPQAT NQTLLDKFKH QHEENSYIEF PAVMEPAFII
660 670 680 690 700
KHYAGKVKYG VKDFREKNTD HMRPDIVALL RSSKNAFISG MIGIDPVAVF
710 720 730 740 750
RWAILRAFFR AMVAFREAGK RHIHRKTGHD DTAPCAILRN MDSFSFLQHP
760 770 780 790 800
VHQRSLEILQ RCKEEKYSIT RKNPRTPLSD LQGMNTLNEK NQHDTFDIAW
810 820 830 840 850
NGRTGIRQSR LSSTTSLLDK DGIFANSASS KLLERAHGIL TRNKNFKSKP
860 870 880 890 900
ALPKHLLEVN SLKHLTRLTI QDRITKSLLH LHKKKKPPSI SAQFQASLNK
910 920 930 940 950
LMETLDQAEP YFVKCIRSNA EKLPLRFSDA LVLRQLRYTG MLETVRIRQS
960 970 980 990 1000
GYSSKYSFQD FVSHFHVLLP QNIIPSKLNI QDFFRKINLN PDNYQVGKTT
1010 1020 1030 1040 1050
VFLKEQERQH LQDLLHQEVL RRIILLQRWF RVLLCRQHFL HMRQASVIIQ
1060 1070 1080 1090 1100
RFWRNYLSQK QMRDAVVQKD AFAMGHAAVL LQASWRAHLE RHRYLELRAA
1110 1120 1130 1140 1150
AIIIQQRWRE HCRRRHMAAV CIQARWKAYR ESKRYQEQRD KIILLQSTCR
1160 1170 1180 1190 1200
GFRARQRFKA LKEQRLKETK LELGLANIKG YRSLEIQGSD PSEWEDRSFD
1210 1220 1230 1240 1250
NRVKAIEECK SVIESNRISR ENSVDCSRES PTKQQERARS HSGVDLQEGV
1260 1270 1280 1290 1300
IVRERPKSLE DLHQKKVGRA KRESRRMREL EQAIFSLELL KVRSLGGVSP
1310 1320 1330 1340 1350
SEERRWSTEL MPESLQSPQG TPDSESSQGS LELLSYEESQ KNKLESIILD
1360 1370 1380 1390 1400
EGDLQFPSPK VSRSPKFESQ DKTLSASRET SYAEHLKNGN VKGKLVCSSE
1410 1420 1430 1440 1450
PITCKPQPRD VFISNSLPTF FYIPQQDPQK TSSQLDTGIQ RNKLLENENI
1460 1470 1480 1490 1500
PGTALTLDIN RETRKYSFSG EDLVPSLNTD SSNAVLRKLE KLNTEKEERQ
1510 1520 1530 1540 1550
KQLQQQNEKE MMEQIRQQTD ILEKERKAFK TFDKPRIGES FPASSFYQSK
1560 1570 1580 1590 1600
QRVERPSSLL SLNTPNKGEH SFLGSPSVTT KDAALPPKDS SSAHLLPKDR
1610 1620 1630 1640 1650
PVTLFFESKG SPCQSSTVRE LSKTDRTGTK LNVACKLSNN RISKRESHRP
1660 1670 1680 1690 1700
TQSYSHKTDD LSREGNTRTI FFTPRDNMSI PLVNKEALNS GNPQVHKQDE
1710 1720 1730 1740 1750
PARKPVKLAG PGQGEVARPA HKKKARMART RSDFLTRGTF ADGEGDTEED
1760 1770 1780 1790 1800
DYDDLIEPLL SLDQASHSER GPVPSLGQAS HSDSEMTSQR FSSVDQQAKL
1810 1820 1830 1840 1850
HKTMSQGEIT KLAVRQKASD LNIRPQRAKM RFWAKGKQGE KKMTRVKHAT
1860 1870 1880 1890 1900
QPEGSALFAA SEVIPADQFP DELAQYHPTP PLSPELPGSC RKEFKENKQP
1910 1920 1930 1940 1950
SPKAKRKRSV KISNVALDSV HWQNDSVQII ASTSDLKSMD EFLLKKMNDL
1960 1970 1980 1990 2000
DNEDSKKDTL VDVVFKKALK EFRQNIFSFY SSALAMDDGK SIRYKDLYAL
2010 2020 2030 2040 2050
FEQILEKTMR LEQRNWRESP VRVWVNTFKV FLDEYMNEFK TSDCTVTKVP
2060 2070 2080 2090 2100
KTERKKRRKK ETDLVEEHNG HIFKATQYSI PTYCEYCSSL IWIMDRASVC
2110 2120 2130 2140 2150
KLCKYACHKK CCLKTTAKCS KKYDPELSSR QFGVELSRLT SEERTVPLVV
2160 2170 2180 2190 2200
EKLINYIEMH GLYTEGIYRK SGSTNKIKEL RQGLDTDAES VNLDDYNIHV
2210 2220 2230 2240 2250
IASVFKQWLR DLPNPLMTFE LYEEFLRAMG LQERKETIHG VYSVIDQLSR
2260 2270 2280 2290 2300
THLNTLERLI FHLVRIALQE DTNRMSANAL AIVFAPCILR CPDTIDPLQS
2310 2320 2330 2340 2350
VQDISKTTTC VELIVVEQMN KYKARLKDIS SLEFAENKAK TRLSLIRRSM
2360 2370 2380 2390 2400
KPVLIAVRFM SITRSSVSGK GRIRRGNYPS PSSPVVVRLP SMSDVPEETL
2410 2420 2430 2440 2450
TSEAAVETDI TEQQQTAMQQ EERVLTEQIE NLQKEKEELT FEMLVLEPRA
2460 2470 2480 2490 2500
SDDETLESEA SIGTADSSEN LNLESEGRSL AFSTLKAAGK SEPSSKLRKQ
2510 2520 2530 2540 2550
LKKQQDSLDS VDSTVSSLCL SNTTSSHGTR KRFQIYSKSP FYRAASAGEA
2560 2570 2580 2590 2600
LGMEGPLGQK SLEDRPQFIS RGTFNPEKGK QKLKNVKNTP QKTKENPEGT
2610 2620
VMPGRRKTVD PDCTSTQQLA LFGNNEFMV
Length:2,629
Mass (Da):302,327
Last modified:February 22, 2012 - v1
Checksum:iD5376F1AAF799452
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAQR03026272 Genomic DNA No translation available.
AAQR03026273 Genomic DNA No translation available.
AAQR03026274 Genomic DNA No translation available.
AAQR03026275 Genomic DNA No translation available.
AAQR03026276 Genomic DNA No translation available.
AAQR03026277 Genomic DNA No translation available.
AAQR03026278 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSOGAT00000006137; ENSOGAP00000005478; ENSOGAG00000006133

Similar proteinsi

Entry informationi

Entry nameiH0WTJ1_OTOGA
AccessioniPrimary (citable) accession number: H0WTJ1
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: April 25, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported