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Protein
Submitted name:

Interleukin 2 receptor subunit alpha

Gene

IL2RA

Organism
Cavia porcellus (Guinea pig)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Interleukin 2 receptor subunit alphaImported
Gene namesi
Name:IL2RAImported
OrganismiCavia porcellus (Guinea pig)Imported
Taxonomic identifieri10141 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaHystricomorphaCaviidaeCavia
Proteomesi
  • UP000005447 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei235 – 257HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_501144868922 – 268Sequence analysisAdd BLAST247

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi24 ↔ 67PROSITE-ProRule annotation
Disulfide bondi121 ↔ 164PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10141.ENSCPOP00000005118

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 81SushiInterPro annotationAdd BLAST60
Domaini119 – 182SushiInterPro annotationAdd BLAST64

Keywords - Domaini

SignalSequence analysis, SushiPROSITE-ProRule annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410J24B Eukaryota
ENOG41116U7 LUCA
GeneTreeiENSGT00390000018872
InParanoidiH0V613
OrthoDBiEOG091G0NHH
TreeFamiTF337408

Family and domain databases

CDDicd00033 CCP, 1 hit
InterProiView protein in InterPro
IPR015486 IL-2_rcpt_alpha
IPR035976 Sushi/SCR/CCP_sf
IPR000436 Sushi_SCR_CCP_dom
PANTHERiPTHR10573 PTHR10573, 1 hit
PfamiView protein in Pfam
PF00084 Sushi, 1 hit
SMARTiView protein in SMART
SM00032 CCP, 2 hits
SUPFAMiSSF57535 SSF57535, 2 hits
PROSITEiView protein in PROSITE
PS50923 SUSHI, 2 hits

Sequencei

Sequence statusi: Complete.

H0V613-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPRLLTWGL FTFIMVPGCM TEDCDQDPPS ISYATFKALT YKNGTMVICD
60 70 80 90 100
CKKGFRRIKN GSMYLLCKGN SSWANKCQCA STSHNARERV TPQPEEHKGK
110 120 130 140 150
NTIEVQSQIQ PMDTINLPGD CREPAPWKHE AAKRTYHFKV GQTVHYQCIQ
160 170 180 190 200
GYKAIQRGPA ISVCKMTCGE AKWTQPQLTC IAENELHSSA GQEDSLESTD
210 220 230 240 250
ALPESETSCP ITTTESAKEM ETSVTVEMPI FPSEYHIAMA GCIFLLISVL
260
LLSGLTWQWR WKKNRRAI
Length:268
Mass (Da):30,154
Last modified:November 22, 2017 - v2
Checksum:iD933CA2AA9CC4AE1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAKN02021943 Genomic DNA No translation available.
RefSeqiXP_013011775.1, XM_013156321.1

Genome annotation databases

EnsembliENSCPOT00000005737; ENSCPOP00000005118; ENSCPOG00000005676
GeneIDi100715332

Similar proteinsi

Entry informationi

Entry nameiH0V613_CAVPO
AccessioniPrimary (citable) accession number: H0V613
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: November 22, 2017
Last modified: March 28, 2018
This is version 43 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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