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Protein
Submitted name:

Negative elongation factor C/D

Gene

TH1L

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Negative elongation factor C/DImported
Submitted name:
TH1-like (Drosophila), isoform CRA_bImported
Gene namesi
Name:TH1LImported
Synonyms:NELFCDImported
ORF Names:hCG_28547Imported
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

HGNCiHGNC:15934. NELFCD.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

EPDiH0UI80.
PaxDbiH0UI80.

Expressioni

Gene expression databases

ExpressionAtlasiH0UI80. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000342300.

Structurei

3D structure databases

ProteinModelPortaliH0UI80.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IFGF. Eukaryota.
ENOG410XSDJ. LUCA.
GeneTreeiENSGT00390000001799.
KOiK15181.
OMAiVMEPSYF.

Family and domain databases

InterProiIPR006942. TH1.
[Graphical view]
PANTHERiPTHR12144. PTHR12144. 1 hit.
PfamiPF04858. TH1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H0UI80-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRRARSREGM AGAVPGAIMD EDYYGSAAEW GDEADGGQQE DDSGEGEDDA
60 70 80 90 100
EVQQECLHKF STRDYIMEPS IFNTLKRYFQ AGGSPENVIQ LLSENYTAVA
110 120 130 140 150
QTVNLLAEWL IQTGVEPVQV QETVENHLKS LLIKHFDPRK ADSIFTEEGE
160 170 180 190 200
TPAWLEQMIA HTTWRDLFYK LAEAHPDCLM LNFTVKLISD AGYQGEITSV
210 220 230 240 250
STACQQLEVF SRVLRTSLAT ILDGGEENLE KNLPEFAKMV CHGEHTYLFA
260 270 280 290 300
QAMMSVLAQE EQGGSAVRRI AQEVQRFAQE KGHDASQITL ALGTAASYPR
310 320 330 340 350
ACQALGAMLS KGALNPADIT VLFKMFTSMD PPPVELIRVP AFLDLFMQSL
360 370 380 390 400
FKPGARINQD HKHKYIHILA YAASVVETWK KNKRVSINKD ELKSTSKAVE
410 420 430 440 450
TVHNLCCNEN KGASELVAEL STLYQCIRFP VVAMGVLKWV DWTVSEPRYF
460 470 480 490 500
QLQTDHTPVH LALLDEISTC HQLLHPQVLQ LLVKLFETEH SQLDVMEQLE
510 520 530 540 550
LKKTLLDRMV HLLSRGYVLP VVSYIRKCLE KLDTDISLIR YFVTEVLDVI
560 570 580 590
APPYTSDFVQ LFLPILENDS IAGTIKTEGE HDPVTEFIAH CKSNFIMVN
Length:599
Mass (Da):67,347
Last modified:February 22, 2012 - v1
Checksum:iA263C8E6262ABFBB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL109840 Genomic DNA. No translation available.
CH471077 Genomic DNA. Translation: EAW75452.1.
CH471077 Genomic DNA. Translation: EAW75453.1.
CH471077 Genomic DNA. Translation: EAW75454.1.
RefSeqiNP_945327.2. NM_198976.2.
UniGeneiHs.517148.

Genome annotation databases

EnsembliENST00000602795; ENSP00000473290; ENSG00000101158.
GeneIDi51497.
KEGGihsa:51497.
UCSCiuc002yag.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL109840 Genomic DNA. No translation available.
CH471077 Genomic DNA. Translation: EAW75452.1.
CH471077 Genomic DNA. Translation: EAW75453.1.
CH471077 Genomic DNA. Translation: EAW75454.1.
RefSeqiNP_945327.2. NM_198976.2.
UniGeneiHs.517148.

3D structure databases

ProteinModelPortaliH0UI80.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000342300.

Proteomic databases

EPDiH0UI80.
PaxDbiH0UI80.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000602795; ENSP00000473290; ENSG00000101158.
GeneIDi51497.
KEGGihsa:51497.
UCSCiuc002yag.4. human.

Organism-specific databases

CTDi51497.
HGNCiHGNC:15934. NELFCD.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IFGF. Eukaryota.
ENOG410XSDJ. LUCA.
GeneTreeiENSGT00390000001799.
KOiK15181.
OMAiVMEPSYF.

Miscellaneous databases

GenomeRNAii51497.

Gene expression databases

ExpressionAtlasiH0UI80. baseline and differential.

Family and domain databases

InterProiIPR006942. TH1.
[Graphical view]
PANTHERiPTHR12144. PTHR12144. 1 hit.
PfamiPF04858. TH1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence and comparative analysis of human chromosome 20."
    Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E.
    , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.
    Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "The sequence of the human genome."
    Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., Kodira C.D., Zheng X.H.
    , Chen L., Skupski M., Subramanian G., Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S., Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J., Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R., Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A., Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K., Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V., Brandon R., Cargill M., Chandramouliswaran I., Charlab R., Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K., Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z., Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A., Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V., Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B., Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J., Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C., Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L., Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S., Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A., Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D., Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L., Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N., Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S., Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F., Kline L., Koduru S., Love A., Mann F., May D., McCawley S., McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K., Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M., Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C., Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N., Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M., Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F., Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A., Mi H., Lazareva B., Hatton T., Narechania A., Diemer K., Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R., Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J., Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H., Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D., Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A., Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S., Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L., Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W., McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M., Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J., Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E., Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.
    Science 291:1304-1351(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. Cited for: NUCLEOTIDE SEQUENCE.
  4. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  5. Ensembl
    Submitted (MAY-2013) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiH0UI80_HUMAN
AccessioniPrimary (citable) accession number: H0UI80
Entry historyi
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: June 8, 2016
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.