cyaA

Functionⁱ

GO - Molecular functionⁱ

adenylate cyclase activity Source: UniProtKB-EC
electron transfer activity Source: InterPro
iron-sulfur cluster binding Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

intracellular signal transduction Source: InterPro

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	LyaseImported

Molecular function

LyaseImported

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Ferredoxin:Adenylate/Guanylate cyclaseImported (EC:4.6.1.1Imported)
Gene namesⁱ	Name:cyaAImported ORF Names:BRAO375_950005Imported
Organismⁱ	Bradyrhizobium sp. (strain ORS 375)Imported
Taxonomic identifierⁱ	566679 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium
Proteomesⁱ	UP000003055 Componentⁱ: Unassembled WGS sequence

Subcellular locationⁱ

Topology

Feature key	Position(s)	DescriptionActions	Length
Transmembraneⁱ	12 – 34	HelicalSequence analysisAdd BLAST	23
Transmembraneⁱ	54 – 82	HelicalSequence analysisAdd BLAST	29
Transmembraneⁱ	94 – 112	HelicalSequence analysisAdd BLAST	19
Transmembraneⁱ	142 – 164	HelicalSequence analysisAdd BLAST	23
Transmembraneⁱ	176 – 193	HelicalSequence analysisAdd BLAST	18
Transmembraneⁱ	229 – 248	HelicalSequence analysisAdd BLAST	20

GO - Cellular componentⁱ

integral component of membrane Source: UniProtKB-KW
intracellular Source: GOC

View the complete GO annotation on QuickGO ...

Keywords - Cellular componentⁱ

Membrane

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	260 – 356	2Fe-2S ferredoxin-typeInterPro annotationAdd BLAST		97
Domainⁱ	377 – 509	Guanylate cyclaseInterPro annotationAdd BLAST		133

Keywords - Domainⁱ

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

Database of Orthologous Groups More...OrthoDBⁱ	POG091H0AUC.

OrthoDBⁱ

POG091H0AUC.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00207. fer2. 1 hit.
Gene3Dⁱ	3.10.20.30. 1 hit. 3.30.70.1230. 1 hit.
InterProⁱ	View protein in InterPro IPR036010. 2Fe-2S_ferredoxin-like_sf. IPR001041. 2Fe-2S_ferredoxin-type. IPR001054. A/G_cyclase. IPR012675. Beta-grasp_dom_sf. IPR029787. Nucleotide_cyclase. IPR034804. SQR/QFR_C/D.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00111. Fer2. 1 hit. PF00211. Guanylate_cyc. 1 hit.
SMARTⁱ	View protein in SMART SM00044. CYCc. 1 hit.
SUPFAMⁱ	SSF54292. SSF54292. 1 hit. SSF55073. SSF55073. 1 hit. SSF81343. SSF81343. 1 hit.
PROSITEⁱ	View protein in PROSITE PS51085. 2FE2S_FER_2. 1 hit. PS50125. GUANYLATE_CYCLASE_2. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

H0SSI2-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSHRFRTTLR SIGIRQLRLI CGIILFSYLL SHFLNHALGN ISLQALAVGV 
        60         70         80         90        100
AYHVAFWQFL PVAIVFYAAV LTHGALGVWA LYQRRQFSRT TLEPLQLVLG 
       110        120        130        140        150
LSIPALIFSH IAGVRLGQTL YGQEKLYPQV LYSYWTGPSW RVWLMSAALL 
       160        170        180        190        200
TSWTHGCIGL HFWLRLKPFY RRAAPWLLAC AVLIPALALL GFYRGGRDVI 
       210        220        230        240        250
SASAASQWRA ENLSSRQTGT PSEQATLEAI MNGFLIGYLG LIGAVLAARG 
       260        270        280        290        300
ARALHERRGG MVTLSYNNGR IIRVPKGLSV LEASQRNNVP HASTCGGRAR 
       310        320        330        340        350
CSTCRIRVIG DLNGLPAPSP REAFVLAQVG ADDPSIRLAC QLRPTDDLSF 
       360        370        380        390        400
FQLFMPNLTP GEHGNQRTRI GQERYLVSLF IDMRGSTSLA EKRLPFDVVF 
       410        420        430        440        450
IVNRFLGAVS QAVLSHGGQP NQFVGDGMLA LFGLAVDPQV ACRQAIQAAH 
       460        470        480        490        500
AIAANIAELN AVLSHDLDDP IRFGIGIHGG EVIVGEIGYR DHMVFTALGD 
       510        520        530        540        550
AVNVASRLQD LTKTLGCQVI ISDDVYARAG LAAGMLPQHE VEIRGRAEPM 
       560        570 
RVRTAMDAGE LADPGAPGEG EAA

Length:573

Mass (Da):62,326

Last modified:February 22, 2012 - v1

Checksum:ⁱ0FD589ECBCF39A32

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CAFI01000493 Genomic DNA. Translation: CCD97159.1.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

CAFI01000493 Genomic DNA. Translation: CCD97159.1.

Genome annotation databases

EnsemblBacteriaⁱ	CCD97159; CCD97159; BRAO375_950005.

EnsemblBacteriaⁱ

CCD97159; CCD97159; BRAO375_950005.

Similar proteinsⁱ

50% Identity

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
H0SSI2	A4YN47 Q132R4 A0A1H8R1P6 A0A1N6I184 UPI0009415AAC UPI000558CA26 A5EQY1 UPI000402AC24 A0A1H8I1U9 A0A1M5IHD0 +106	Bradyrhizobium sp. (strain ORS 278) Rhodopseudomonas palustris (strain BisB5) Rhodopseudomonas pseudopalustris Bradyrhizobium erythrophlei Bradyrhizobium sp. (strain ORS 375) Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182) Bradyrhizobium sp. Tv2a-2 Bradyrhizobium sp. OK095 Bradyrhizobium sp. STM 3809 Bradyrhizobium japonicum And more	577	UniRef50_A4YN47	Cluster: Ferredoxin:Adenylate/Guanylate cyclase	117

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CAFI01000493 Genomic DNA. Translation: CCD97159.1.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

CAFI01000493 Genomic DNA. Translation: CCD97159.1.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	CCD97159; CCD97159; BRAO375_950005.

EnsemblBacteriaⁱ

CCD97159; CCD97159; BRAO375_950005.

Phylogenomic databases

Database of Orthologous Groups More...OrthoDBⁱ	POG091H0AUC.

OrthoDBⁱ

POG091H0AUC.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00207. fer2. 1 hit.
Gene3Dⁱ	3.10.20.30. 1 hit. 3.30.70.1230. 1 hit.
InterProⁱ	View protein in InterPro IPR036010. 2Fe-2S_ferredoxin-like_sf. IPR001041. 2Fe-2S_ferredoxin-type. IPR001054. A/G_cyclase. IPR012675. Beta-grasp_dom_sf. IPR029787. Nucleotide_cyclase. IPR034804. SQR/QFR_C/D.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00111. Fer2. 1 hit. PF00211. Guanylate_cyc. 1 hit.
SMARTⁱ	View protein in SMART SM00044. CYCc. 1 hit.
SUPFAMⁱ	SSF54292. SSF54292. 1 hit. SSF55073. SSF55073. 1 hit. SSF81343. SSF81343. 1 hit.
PROSITEⁱ	View protein in PROSITE PS51085. 2FE2S_FER_2. 1 hit. PS50125. GUANYLATE_CYCLASE_2. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	H0SSI2_BRAS3
Accessionⁱ	H0SSI2Primary (citable) accession number: H0SSI2
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	February 22, 2012
	Last sequence update:	February 22, 2012
	Last modified:	February 28, 2018
	This is version 26 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termⁱ

Complete proteomeImported

UniProtKB - H0SSI2 (H0SSI2_BRAS3)

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Ferredoxin:Adenylate/Guanylate cyclase

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Topology

GO - Cellular componentⁱ

Keywords - Cellular componentⁱ

Family & Domainsⁱ

Domains and Repeats

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Caution

Keywords - Technical termⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - H0SSI2 (H0SSI2_BRAS3)

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Ferredoxin:Adenylate/Guanylate cyclase

cyaA

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Caution

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ