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Protein

Polyribonucleotide nucleotidyltransferase

Gene

pnp

Organism
Azoarcus sp. KH32C
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.UniRule annotation

Catalytic activityi

RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi487MagnesiumUniRule annotation1
Metal bindingi493MagnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferaseUniRule annotation, RNA-bindingUniRule annotation, Transferase
LigandMagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciASP748247:G1HGC-2253-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Polyribonucleotide nucleotidyltransferaseUniRule annotation (EC:2.7.7.8UniRule annotation)
Alternative name(s):
Polynucleotide phosphorylaseUniRule annotation
Short name:
PNPaseUniRule annotation
Gene namesi
Name:pnpUniRule annotationImported
ORF Names:AZKH_2255Imported
OrganismiAzoarcus sp. KH32CImported
Taxonomic identifieri748247 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaRhodocyclalesZoogloeaceaeAzoarcus
Proteomesi
  • UP000007106 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini623 – 691S1 motifInterPro annotationAdd BLAST69

Sequence similaritiesi

Belongs to the polyribonucleotide nucleotidyltransferase family.UniRule annotation

Phylogenomic databases

KOiK00962
OrthoDBiPOG091H00M0

Family and domain databases

Gene3Di3.30.1370.101 hit
3.30.230.702 hits
HAMAPiMF_01595 PNPase, 1 hit
InterProiView protein in InterPro
IPR001247 ExoRNase_PH_dom1
IPR015847 ExoRNase_PH_dom2
IPR036345 ExoRNase_PH_dom2_sf
IPR004087 KH_dom
IPR004088 KH_dom_type_1
IPR036612 KH_dom_type_1_sf
IPR012340 NA-bd_OB-fold
IPR012162 PNPase
IPR027408 PNPase/RNase_PH_dom_sf
IPR015848 PNPase_PH_RNA-bd_bac/org-type
IPR020568 Ribosomal_S5_D2-typ_fold
IPR022967 S1_dom
IPR003029 S1_domain
PANTHERiPTHR11252 PTHR11252, 1 hit
PfamiView protein in Pfam
PF00013 KH_1, 1 hit
PF03726 PNPase, 1 hit
PF01138 RNase_PH, 2 hits
PF03725 RNase_PH_C, 2 hits
PF00575 S1, 1 hit
PIRSFiPIRSF005499 PNPase, 1 hit
SMARTiView protein in SMART
SM00322 KH, 1 hit
SM00316 S1, 1 hit
SUPFAMiSSF50249 SSF50249, 1 hit
SSF54211 SSF54211, 2 hits
SSF54791 SSF54791, 1 hit
SSF55666 SSF55666, 2 hits
TIGRFAMsiTIGR03591 polynuc_phos, 1 hit
PROSITEiView protein in PROSITE
PS50126 S1, 1 hit

Sequencei

Sequence statusi: Complete.

H0PZN2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPTAIKKTFA YGAHTVTLET GEIARQAGGA VIVNMDDTVV LATVVAAKEA
60 70 80 90 100
KAGQDFFPLT VDYVEKFYAA GRIPGGFFKR EGRPTEKETL TSRLIDRPIR
110 120 130 140 150
PLFPDGFYNE VQIIVTVLSL NPEIDPDMPA MIAASAALAI SGVPFMGPIG
160 170 180 190 200
ACRVGYVNGE YVLNPTVEQL KSSQLNLVVA GTEVAVLMVE SEANELSEEV
210 220 230 240 250
MLGSVVFGHQ QMQAAIRAIN ELVEVAGKPE WNWQPPAKNE PLIARIKELA
260 270 280 290 300
GAQVEEAFRI TSKQARTERL NEIRKQAIAA ISEGVEDVPS ANELKDIFHE
310 320 330 340 350
LEAGVVRSRI LAGEPRIDGR DTRTVRPIDI RVGVLPRTHG SALFTRGETQ
360 370 380 390 400
ALVIATLGTG RDEQIIDAIA GEYRENFLLH YNFPPFSTGE TGRMGVTKRR
410 420 430 440 450
EVGHGRLAKR ALVAALPAPE EFSYTIRVVS EITESNGSSS MASVCGGSLA
460 470 480 490 500
MMDAGVPMRA HVAGIAMGLI KEGNRFAVLT DILGDEDHLG DMDFKVAGTE
510 520 530 540 550
NGVTALQMDI KIQGITKEIM QVALGQAREG RMHILGIMKQ SLASHRGEVS
560 570 580 590 600
EFAPRMLTMK INPEKIRDVI GKGGAVIRAL QEETGTIIEL EDDGSVTISS
610 620 630 640 650
VSAEGAEAAK KRIEAITAEV EVGKVYEGTV MRLLDFGAIV NILPGRDGLL
660 670 680 690 700
HVSQIANERV NNVADYVKEG QVVRVKVLET DERGKIRLSM KALLEKPAAE
Length:700
Mass (Da):75,717
Last modified:February 22, 2012 - v1
Checksum:i79BE5B2F56238D95
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP012304 Genomic DNA Translation: BAL24565.1
RefSeqiWP_015435870.1, NC_020516.1

Genome annotation databases

EnsemblBacteriaiBAL24565; BAL24565; AZKH_2255
KEGGiaza:AZKH_2255
PATRICifig|748247.4.peg.2214

Similar proteinsi

Entry informationi

Entry nameiH0PZN2_9RHOO
AccessioniPrimary (citable) accession number: H0PZN2
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: February 28, 2018
This is version 41 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported