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Protein

Aconitate hydratase, mitochondrial

Gene

VIN7_2508

Organism
Saccharomyces cerevisiae x Saccharomyces kudriavzevii (strain VIN7) (Yeast)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Cofactori

[4Fe-4S] clusterUniRule annotationNote: Binds 1 [4Fe-4S] cluster per subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotation
LigandIron, Iron-sulfurUniRule annotation, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Aconitate hydratase, mitochondrialUniRule annotation (EC:4.2.1.-UniRule annotation)
Short name:
AconitaseUniRule annotation
Gene namesi
ORF Names:VIN7_2508Imported
OrganismiSaccharomyces cerevisiae x Saccharomyces kudriavzevii (strain VIN7) (Yeast)Imported
Taxonomic identifieri1095631 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000009009 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

MitochondrionUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 486AconitaseInterPro annotationAdd BLAST448
Domaini567 – 694Aconitase_CInterPro annotationAdd BLAST128

Sequence similaritiesi

Belongs to the aconitase/IPM isomerase family.UniRule annotation

Keywords - Domaini

Transit peptideUniRule annotation

Phylogenomic databases

PhylomeDBiH0GIG2.

Family and domain databases

Gene3Di3.20.19.10. 1 hit.
3.30.499.10. 2 hits.
3.40.1060.10. 1 hit.
InterProiView protein in InterPro
IPR015931. Acnase/IPM_dHydase_lsu_aba_1/3.
IPR001030. Acoase/IPM_deHydtase_lsu_aba.
IPR015928. Aconitase/3IPM_dehydase_swvl.
IPR015932. Aconitase/IPMdHydase_lsu_aba_2.
IPR018136. Aconitase_4Fe-4S_BS.
IPR006248. Aconitase_mito-like.
IPR000573. AconitaseA/IPMdHydase_ssu_swvl.
PfamiView protein in Pfam
PF00330. Aconitase. 1 hit.
PF00694. Aconitase_C. 1 hit.
PRINTSiPR00415. ACONITASE.
SUPFAMiSSF52016. SSF52016. 1 hit.
SSF53732. SSF53732. 1 hit.
TIGRFAMsiTIGR01340. aconitase_mito. 1 hit.
PROSITEiView protein in PROSITE
PS00450. ACONITASE_1. 1 hit.
PS01244. ACONITASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

H0GIG2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFPSVSKNFQ TKVPPYAKLL TNLDKIKQIT NNAPLTLAEK ILYSHLCDPE
60 70 80 90 100
ESITSSDLST IRGNKYLKLN PDRVAMQDAS AQMALLQFMT TGLNQTSVPA
110 120 130 140 150
SIHCDHLIVG KDGETKDLPS SIATNQEVFD FLESCAKRYG IQFWGPGSGI
160 170 180 190 200
IHQIVLENFS APGLMMLGTD SHTPNAGGLG AIAIGVGGAD AVDALTGTPW
210 220 230 240 250
ELKAPKILGV KLTGKLNGWS TPKDVITKLA GLLTVRGGTG YIVEYFGEGV
260 270 280 290 300
STLSCTGMAT ICNMGAEIGA TTSTFPYQEA HKRYLQATNR AEVAEAADVA
310 320 330 340 350
LNKFNFLRAD KDAQYDKVIE IDLSAIEPHV NGPFTPDLST PISQYAEKSL
360 370 380 390 400
KENWPQKVSA GLIGSCTNSS YQDMSRVVDL VRQASKAGLK PRIPFFVTPG
410 420 430 440 450
SEQIRATLER DGIIDIFQEN GAKVLANACG PCIGQWDRED VSKTSKETNT
460 470 480 490 500
IFTSFNRNFR ARNDGNRNTM NFLTSPEIVT AMSYSGDAQF NPLTDSIKLP
510 520 530 540 550
NGKDFKFQPP KGDELPKRGF EHGRDKFYPE MDPKPDSSVE IKVDPNSDRL
560 570 580 590 600
QLLEPFKPWN GKELKTNVLL KVEGKCTTDH ISAAGVWLKY KGHLENISYN
610 620 630 640 650
TLIGAQNKET GEVNKAYDLD GTEYDIPGLM MKWKSDGRPW TVIAEHNYGE
660 670 680 690 700
GSAREHAALS PRFLGGEILL VKSFARIHET NLKKQGVLPL TFANESDYDK
710 720 730 740 750
ISSGDVLETL NLVDMVAKDG NNGGEIDVKI TKPNGESFTI KAKHTMSKDQ
760 770
IDFFKAGSAI NYIGNIRRNE
Length:770
Mass (Da):84,359
Last modified:February 22, 2012 - v1
Checksum:i456067EB4F031243
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AGVY01000034 Genomic DNA. Translation: EHN06391.1.

Genome annotation databases

EnsemblFungiiEHN06391; EHN06391; VIN7_2508.

Similar proteinsi

Entry informationi

Entry nameiH0GIG2_SACCK
AccessioniPrimary (citable) accession number: H0GIG2
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: May 10, 2017
This is version 21 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported