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G9M4M6

- G9M4M6_MOUSE

UniProt

G9M4M6 - G9M4M6_MOUSE

Protein
Submitted name:

Autophagy-related 16-like 1 (Yeast), isoform CRA_a

Gene

Atg16l1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 20 (01 Oct 2014)
      Sequence version 1 (22 Feb 2012)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. protein binding Source: MGI

    GO - Biological processi

    1. autophagic vacuole assembly Source: MGI
    2. negative stranded viral RNA replication Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Autophagy-related 16-like 1 (Yeast), isoform CRA_aImported
    Submitted name:
    Autophagy-related 16-like 1 gammaImported
    Gene namesi
    Name:Atg16l1Imported
    Synonyms:Atg16L1 gammaImported
    ORF Names:mCG_16203Imported
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:1924290. Atg16l1.

    Subcellular locationi

    GO - Cellular componenti

    1. autophagic vacuole Source: MGI
    2. autophagic vacuole membrane Source: MGI

    Family & Domainsi

    Keywords - Domaini

    RepeatUniRule annotation, WD repeatUniRule annotation

    Phylogenomic databases

    KOiK17890.
    OMAiLETECQE.

    Family and domain databases

    Gene3Di2.130.10.10. 1 hit.
    InterProiIPR013923. Autophagy-rel_prot_16.
    IPR020472. G-protein_beta_WD-40_rep.
    IPR015943. WD40/YVTN_repeat-like_dom.
    IPR001680. WD40_repeat.
    IPR019775. WD40_repeat_CS.
    IPR017986. WD40_repeat_dom.
    [Graphical view]
    PfamiPF08614. ATG16. 1 hit.
    PF00400. WD40. 5 hits.
    [Graphical view]
    PRINTSiPR00320. GPROTEINBRPT.
    SMARTiSM00320. WD40. 7 hits.
    [Graphical view]
    SUPFAMiSSF50978. SSF50978. 1 hit.
    PROSITEiPS00678. WD_REPEATS_1. 3 hits.
    PS50082. WD_REPEATS_2. 6 hits.
    PS50294. WD_REPEATS_REGION. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G9M4M6-1 [UniParc]FASTAAdd to Basket

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    MSSGLRAADF PRWKRHIAEE LRRRDRLQRQ AFEEIILQYT KLLEKSDLHS    50
    VLTQKLQAEK HDMPNRHEIS PGHDGAWNDS QLQEMAQLRI KHQEELTELH 100
    KKRGELAQLV IDLNNQMQQK DKEIQMNEAK ISEYLQTISD LETNCLDLRT 150
    KLQDLEVANQ TLKDEYDALQ ITFTALEEKL RKTTEENQEL VTRWMAEKAQ 200
    EANRLNAENE KDSRRRQARL QKELAEAAKE PLPVEQDDDI EVIVDETSDH 250
    TEETSPVRAV SRAATKRLSQ PAGGLLDSIT NIFGLSESPL LGHHSSDAAR 300
    RRSVSSIPVP QDIMDTHPAS GKDVRVPTTA SYVFDAHDGE VNAVQFSPGS 350
    RLLATGGMDR RVKLWEAFGD KCEFKGSLSG SNAGITSIEF DSAGAYLLAA 400
    SNDFASRIWT VDDYRLRHTL TGHSGKVLSA KFLLDNARIV SGSHDRTLKL 450
    WDLRSKVCIK TVFAGSSCND IVCTEQCVMS GHFDKKIRFW DIRSESVVRE 500
    MELLGKITAL DLNPERTELL SCSRDDLLKV IDLRTNAVKQ TFSAPGFKCG 550
    SDWTRVVFSP DGSYVAAGSA EGSLYVWSVL TGKVEKVLSK QHSSSINAVA 600
    WAPSGLHVVS VDKGSRAVLW AQP 623
    Length:623
    Mass (Da):69,831
    Last modified:February 22, 2012 - v1
    Checksum:i823453BB5D7DE6FE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB476646 mRNA. Translation: BAL42358.1.
    CH466520 Genomic DNA. Translation: EDL40144.1.
    RefSeqiNP_001192320.1. NM_001205391.1.
    UniGeneiMm.272972.
    Mm.456099.

    Genome annotation databases

    GeneIDi77040.
    KEGGimmu:77040.
    UCSCiuc007bxm.2. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB476646 mRNA. Translation: BAL42358.1 .
    CH466520 Genomic DNA. Translation: EDL40144.1 .
    RefSeqi NP_001192320.1. NM_001205391.1.
    UniGenei Mm.272972.
    Mm.456099.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 77040.
    KEGGi mmu:77040.
    UCSCi uc007bxm.2. mouse.

    Organism-specific databases

    CTDi 55054.
    MGIi MGI:1924290. Atg16l1.

    Phylogenomic databases

    KOi K17890.
    OMAi LETECQE.

    Miscellaneous databases

    NextBioi 346354.
    SOURCEi Search...

    Family and domain databases

    Gene3Di 2.130.10.10. 1 hit.
    InterProi IPR013923. Autophagy-rel_prot_16.
    IPR020472. G-protein_beta_WD-40_rep.
    IPR015943. WD40/YVTN_repeat-like_dom.
    IPR001680. WD40_repeat.
    IPR019775. WD40_repeat_CS.
    IPR017986. WD40_repeat_dom.
    [Graphical view ]
    Pfami PF08614. ATG16. 1 hit.
    PF00400. WD40. 5 hits.
    [Graphical view ]
    PRINTSi PR00320. GPROTEINBRPT.
    SMARTi SM00320. WD40. 7 hits.
    [Graphical view ]
    SUPFAMi SSF50978. SSF50978. 1 hit.
    PROSITEi PS00678. WD_REPEATS_1. 3 hits.
    PS50082. WD_REPEATS_2. 6 hits.
    PS50294. WD_REPEATS_REGION. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
      Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
      , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
      Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    2. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
      Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    3. "Atg16L2, a novel isoform of mammalian Atg16L that is not essential for canonical autophagy despite forming an Atg12-5-16L2 complex."
      Ishibashi K., Fujita N., Kanno E., Omori H., Yoshimori T., Itoh T., Fukuda M.
      Autophagy 7:1500-1513(2011)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: Balb/CImported.
      Tissue: BrainImported.

    Entry informationi

    Entry nameiG9M4M6_MOUSE
    AccessioniPrimary (citable) accession number: G9M4M6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 22, 2012
    Last sequence update: February 22, 2012
    Last modified: October 1, 2014
    This is version 20 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)