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G9M4M6

- G9M4M6_MOUSE

UniProt

G9M4M6 - G9M4M6_MOUSE

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Protein
Submitted name:

Autophagy-related 16-like 1 (Yeast), isoform CRA_a

Gene
Atg16l1, Atg16L1 gamma, mCG_16203
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. protein binding Source: MGI

GO - Biological processi

  1. autophagic vacuole assembly Source: MGI
  2. negative stranded viral RNA replication Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Autophagy-related 16-like 1 (Yeast), isoform CRA_aImported
Submitted name:
Autophagy-related 16-like 1 gammaImported
Gene namesi
Name:Atg16l1Imported
Synonyms:Atg16L1 gammaImported
ORF Names:mCG_16203Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1924290. Atg16l1.

Subcellular locationi

GO - Cellular componenti

  1. autophagic vacuole Source: MGI
  2. autophagic vacuole membrane Source: MGI
Complete GO annotation...

Family & Domainsi

Keywords - Domaini

RepeatUniRule annotation, WD repeatUniRule annotation

Phylogenomic databases

KOiK17890.
OMAiLETECQE.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR013923. Autophagy-rel_prot_16.
IPR020472. G-protein_beta_WD-40_rep.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF08614. ATG16. 1 hit.
PF00400. WD40. 5 hits.
[Graphical view]
PRINTSiPR00320. GPROTEINBRPT.
SMARTiSM00320. WD40. 7 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS00678. WD_REPEATS_1. 3 hits.
PS50082. WD_REPEATS_2. 6 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G9M4M6-1 [UniParc]FASTAAdd to Basket

« Hide

MSSGLRAADF PRWKRHIAEE LRRRDRLQRQ AFEEIILQYT KLLEKSDLHS    50
VLTQKLQAEK HDMPNRHEIS PGHDGAWNDS QLQEMAQLRI KHQEELTELH 100
KKRGELAQLV IDLNNQMQQK DKEIQMNEAK ISEYLQTISD LETNCLDLRT 150
KLQDLEVANQ TLKDEYDALQ ITFTALEEKL RKTTEENQEL VTRWMAEKAQ 200
EANRLNAENE KDSRRRQARL QKELAEAAKE PLPVEQDDDI EVIVDETSDH 250
TEETSPVRAV SRAATKRLSQ PAGGLLDSIT NIFGLSESPL LGHHSSDAAR 300
RRSVSSIPVP QDIMDTHPAS GKDVRVPTTA SYVFDAHDGE VNAVQFSPGS 350
RLLATGGMDR RVKLWEAFGD KCEFKGSLSG SNAGITSIEF DSAGAYLLAA 400
SNDFASRIWT VDDYRLRHTL TGHSGKVLSA KFLLDNARIV SGSHDRTLKL 450
WDLRSKVCIK TVFAGSSCND IVCTEQCVMS GHFDKKIRFW DIRSESVVRE 500
MELLGKITAL DLNPERTELL SCSRDDLLKV IDLRTNAVKQ TFSAPGFKCG 550
SDWTRVVFSP DGSYVAAGSA EGSLYVWSVL TGKVEKVLSK QHSSSINAVA 600
WAPSGLHVVS VDKGSRAVLW AQP 623
Length:623
Mass (Da):69,831
Last modified:February 22, 2012 - v1
Checksum:i823453BB5D7DE6FE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB476646 mRNA. Translation: BAL42358.1.
CH466520 Genomic DNA. Translation: EDL40144.1.
RefSeqiNP_001192320.1. NM_001205391.1.
UniGeneiMm.272972.
Mm.456099.

Genome annotation databases

GeneIDi77040.
KEGGimmu:77040.
UCSCiuc007bxm.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB476646 mRNA. Translation: BAL42358.1 .
CH466520 Genomic DNA. Translation: EDL40144.1 .
RefSeqi NP_001192320.1. NM_001205391.1.
UniGenei Mm.272972.
Mm.456099.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 77040.
KEGGi mmu:77040.
UCSCi uc007bxm.2. mouse.

Organism-specific databases

CTDi 55054.
MGIi MGI:1924290. Atg16l1.

Phylogenomic databases

KOi K17890.
OMAi LETECQE.

Miscellaneous databases

NextBioi 346354.
SOURCEi Search...

Family and domain databases

Gene3Di 2.130.10.10. 1 hit.
InterProi IPR013923. Autophagy-rel_prot_16.
IPR020472. G-protein_beta_WD-40_rep.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view ]
Pfami PF08614. ATG16. 1 hit.
PF00400. WD40. 5 hits.
[Graphical view ]
PRINTSi PR00320. GPROTEINBRPT.
SMARTi SM00320. WD40. 7 hits.
[Graphical view ]
SUPFAMi SSF50978. SSF50978. 1 hit.
PROSITEi PS00678. WD_REPEATS_1. 3 hits.
PS50082. WD_REPEATS_2. 6 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  2. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  3. "Atg16L2, a novel isoform of mammalian Atg16L that is not essential for canonical autophagy despite forming an Atg12-5-16L2 complex."
    Ishibashi K., Fujita N., Kanno E., Omori H., Yoshimori T., Itoh T., Fukuda M.
    Autophagy 7:1500-1513(2011)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Balb/CImported.
    Tissue: BrainImported.

Entry informationi

Entry nameiG9M4M6_MOUSE
AccessioniPrimary (citable) accession number: G9M4M6
Entry historyi
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: July 9, 2014
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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