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Protein

NADH-ubiquinone oxidoreductase chain 3

Gene

ND3

Organism
Leucoraja erinacea (Little skate) (Raja erinacea)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.SAAS annotation

Catalytic activityi

NADH + ubiquinone + 5 H+(In) = NAD+ + ubiquinol + 4 H+(Out).UniRule annotationSAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
Biological processElectron transport, Respiratory chainSAAS annotation, Transport
LigandNADUniRule annotationSAAS annotation, UbiquinoneUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
NADH-ubiquinone oxidoreductase chain 3UniRule annotationSAAS annotation (EC:1.6.5.3UniRule annotation)
Gene namesi
Name:ND3Imported
Encoded oniMitochondrionImported
OrganismiLeucoraja erinacea (Little skate) (Raja erinacea)Imported
Taxonomic identifieri7782 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataChondrichthyesElasmobranchiiBatoideaRajiformesRajidaeLeucoraja

Subcellular locationi

  • Mitochondrion membrane SAAS annotation; Multi-pass membrane protein SAAS annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei6 – 25HelicalSequence analysisAdd BLAST20
Transmembranei56 – 78HelicalSequence analysisAdd BLAST23
Transmembranei90 – 108HelicalSequence analysisAdd BLAST19

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, MitochondrionUniRule annotationSAAS annotationImported

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I subunit 3 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

InterProiView protein in InterPro
IPR000440. NADH_UbQ/plastoQ_OxRdtase_su3.
PANTHERiPTHR11058. PTHR11058. 1 hit.
PfamiView protein in Pfam
PF00507. Oxidored_q4. 1 hit.

Sequencei

Sequence statusi: Complete.

G9L9I6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLITLSIAI PALVSLILAF IAFWLPALNP DSEKLSPYEC GFDPLGSARL
60 70 80 90 100
PFSLRFFLVA ILFLLFDLEI ALLLPLPWGD QLYSPLTTTL WASIIIILLT
110
LGLVYEWLQG GLEWAE
Length:116
Mass (Da):12,963
Last modified:February 22, 2012 - v1
Checksum:i5FE8B2852B09498B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JQ034406 Genomic DNA. Translation: AET87636.1.
RefSeqiYP_004935525.1. NC_016429.1.

Genome annotation databases

GeneIDi11452185.

Similar proteinsi

Entry informationi

Entry nameiG9L9I6_LEUER
AccessioniPrimary (citable) accession number: G9L9I6
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: June 7, 2017
This is version 22 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)