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Protein

Xylose isomerase

Gene

xylA

Organism
Rhizobium fredii (strain HH103) (Sinorhizobium fredii)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei100 – 1001UniRule annotation
Active sitei103 – 1031UniRule annotation
Metal bindingi231 – 2311Magnesium 1UniRule annotation
Metal bindingi267 – 2671Magnesium 1UniRule annotation
Metal bindingi267 – 2671Magnesium 2UniRule annotation
Metal bindingi270 – 2701Magnesium 2UniRule annotation
Metal bindingi295 – 2951Magnesium 1UniRule annotation
Metal bindingi306 – 3061Magnesium 2UniRule annotation
Metal bindingi308 – 3081Magnesium 2UniRule annotation
Metal bindingi338 – 3381Magnesium 1UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotation, Xylose metabolismUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciSFRE1117943:GJT5-2996-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotationImported
Ordered Locus Names:SFHH103_02958Imported
OrganismiRhizobium fredii (strain HH103) (Sinorhizobium fredii)Imported
Taxonomic identifieri1117943 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
ProteomesiUP000007735 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi1117943.SFHH103_02958.

Structurei

3D structure databases

ProteinModelPortaliG9A0Q4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

KOiK01805.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G9A0Q4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTGFFGDIA KIKYEGLEST NPLAFRHYNP DEVVLGKRME DHLRFAVAYW
60 70 80 90 100
HTFVWPGGDP FGGQTFERPW FKDTMDAAKL KADVAFEFFQ LLGVPFYCFH
110 120 130 140 150
DADVRPEGRN FAENTSNLNE IVDHFAEKQA ETGVKLLWGT ANLFSNRRYM
160 170 180 190 200
GGAATNPDPD VFAFAAATVK TCIDATQRLG GENYVLWGGR EGYETLLNTD
210 220 230 240 250
LKRELDQLGR FVNLVVEYKH KIGFKGAILI EPKPQEPTKH QYDFDVATVY
260 270 280 290 300
GFLKKYGLEN EVKVNIEQGH AILAGHSFEH ELALANALGI FGSIDMNRND
310 320 330 340 350
YQSGWDTDQF PNNVPEMALA YYHVLSGGGF KSGGTNFDAK LRRQSIDPED
360 370 380 390 400
LLIGHIGGMD CCARGLKAAA KMVEDKALSG PLEKRYAGWN VPEAKKMLDG
410 420 430
GFSLEEIEAW VRKADLNPQA KSGKQEYLEN VVNRYV
Length:436
Mass (Da):48,884
Last modified:February 22, 2012 - v1
Checksum:i9D9181BECB3AE72E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE616890 Genomic DNA. Translation: CCE97450.1.
RefSeqiWP_014329858.1. NC_016812.1.

Genome annotation databases

EnsemblBacteriaiCCE97450; CCE97450; SFHH103_02958.
KEGGisfh:SFHH103_02958.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE616890 Genomic DNA. Translation: CCE97450.1.
RefSeqiWP_014329858.1. NC_016812.1.

3D structure databases

ProteinModelPortaliG9A0Q4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi1117943.SFHH103_02958.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCCE97450; CCE97450; SFHH103_02958.
KEGGisfh:SFHH103_02958.

Phylogenomic databases

KOiK01805.

Enzyme and pathway databases

BioCyciSFRE1117943:GJT5-2996-MONOMER.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HH103Imported.

Entry informationi

Entry nameiG9A0Q4_RHIFH
AccessioniPrimary (citable) accession number: G9A0Q4
Entry historyi
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: July 22, 2015
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.