Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

DNA ligase

Gene

TDEL0G04510

Organism
Torulaspora delbrueckii (strain ATCC 10662 / CBS 1146 / NBRC 0425 / NCYC 2629 / NRRL Y-866) (Yeast) (Candida colliculosa)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: InterPro
  2. DNA ligation involved in DNA repair Source: InterPro
  3. DNA recombination Source: UniProtKB-KW
  4. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Name:TDEL0G04510Imported
ORF Names:TDEL_0G04510Imported
OrganismiTorulaspora delbrueckii (strain ATCC 10662 / CBS 1146 / NBRC 0425 / NCYC 2629 / NRRL Y-866) (Yeast) (Candida colliculosa)Imported
Taxonomic identifieri1076872 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeTorulaspora
ProteomesiUP000005627: Chromosome 7

Structurei

3D structure databases

ProteinModelPortaliG8ZY51.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

InParanoidiG8ZY51.
KOiK10777.
OrthoDBiEOG7QC84G.

Family and domain databases

Gene3Di2.40.50.140. 2 hits.
3.40.50.10190. 1 hit.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR029710. LIG4.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PANTHERiPTHR10459:SF7. PTHR10459:SF7. 1 hit.
PfamiPF00533. BRCT. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SMARTiSM00292. BRCT. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 2 hits.
SSF52113. SSF52113. 2 hits.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G8ZY51-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MESAEILTST HEVSQELQES ESTEKAPPNF APSPDFIWLC EELFVKLEDV
60 70 80 90 100
QRQGREHLGN KPLSVRYYEV ISHFIRLWRK TVGNNIFPAL VLSLPYRDRR
110 120 130 140 150
IYNIKDYTLV KAICSYLALP KQSATEKRLL KWKRRATRGV RLSNFCVEEI
160 170 180 190 200
RKRKSEPSPG RRITIDKLNE CLDHLVEERN AKGGFKGLSD SPTFNFCLQN
210 220 230 240 250
MSFIELRFFF DIVLKNRVIG GQEHKLLNCW HPDALDYLSV VSDLETVASR
260 270 280 290 300
LWDPEHRLRR DDLSINLGYA FVPQLAKKMT ISYEKICTKL NNDFLIEEKM
310 320 330 340 350
DGERIQVHYM DYGAKIRFLS RRGVDYTQLY GENLQSGTVA NYLNFDSNVR
360 370 380 390 400
DCVLDGEMIT FDTDRNVVLP FGMVKSSARQ ALSTEGICSQ GHRPMLMVLD
410 420 430 440 450
LVYLNGVSLI KLPLYQRKEF LNRVLKPCPH AVEILPYVRC SEHTAIRKSL
460 470 480 490 500
EKSISMGSEG IVLKSYKARY EIGARNDYWI KVKPEYLEQF GENLDLVIIG
510 520 530 540 550
RTPGKKDSLM CGLAVYEGEE DLNEIEAKRE SAIVNLDSEG DELDDTDGKK
560 570 580 590 600
IIKYFISFCV IANGISQQEF KEIDRKTRGA WVKSDQRLPS ADLLRFGSKI
610 620 630 640 650
PEEWIDPKNS IMLEVKARSL DNTESSKKKF AAGCTLHGGY CRRIRDDKDW
660 670 680 690 700
TGCYSFSELW QERLHKSSTG VGSFNKQYSK KMKSKKRKID PFSGQAAKKH
710 720 730 740 750
DVFDSTNIFK GLQFYVLSDY IDVSRNVRIT KSEFDDLILQ NSGKLVRNLI
760 770 780 790 800
SKHHSESQFR IISGKYTAEC RALIERGYDI LSPQWILDCI RNRMVVKLEP
810 820 830 840 850
RHCFNVSSEL MTIVNGRVDE YGDSFVNPIT EQQLDNLIDT NMKQTEPNLM
860 870 880 890 900
REANSELDVV PLFLFSTRAV YIPPQVFNAV DAYGLTSKFK LHGGSIASDI
910 920 930 940 950
PSCNLIIMPN ENQRLGTQSL VEMRQSVLQA MGRNDSTPSI PYIVTPDWVE
960
KSIEENCQVP EEDFTPVYA
Length:969
Mass (Da):111,242
Last modified:February 22, 2012 - v1
Checksum:iBE41935B409BD40B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE616748 Genomic DNA. Translation: CCE93818.1.
RefSeqiXP_003683029.1. XM_003682981.1.

Genome annotation databases

GeneIDi11505191.
KEGGitdl:TDEL_0G04510.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE616748 Genomic DNA. Translation: CCE93818.1.
RefSeqiXP_003683029.1. XM_003682981.1.

3D structure databases

ProteinModelPortaliG8ZY51.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi11505191.
KEGGitdl:TDEL_0G04510.

Phylogenomic databases

InParanoidiG8ZY51.
KOiK10777.
OrthoDBiEOG7QC84G.

Family and domain databases

Gene3Di2.40.50.140. 2 hits.
3.40.50.10190. 1 hit.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR029710. LIG4.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PANTHERiPTHR10459:SF7. PTHR10459:SF7. 1 hit.
PfamiPF00533. BRCT. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SMARTiSM00292. BRCT. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 2 hits.
SSF52113. SSF52113. 2 hits.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Evolutionary erosion of yeast sex chromosomes by mating-type switching accidents."
    Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P., Wolfe K.H.
    Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 10662 / CBS 1146 / NBRC 0425 / NCYC 2629 / NRRL Y-866Imported.

Entry informationi

Entry nameiG8ZY51_TORDC
AccessioniPrimary (citable) accession number: G8ZY51
Entry historyi
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: January 7, 2015
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.