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Protein

DNA ligase

Gene

TDEL0C02040

Organism
Torulaspora delbrueckii (strain ATCC 10662 / CBS 1146 / NBRC 0425 / NCYC 2629 / NRRL Y-866) (Yeast) (Candida colliculosa)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Name:TDEL0C02040Imported
ORF Names:TDEL_0C02040Imported
OrganismiTorulaspora delbrueckii (strain ATCC 10662 / CBS 1146 / NBRC 0425 / NCYC 2629 / NRRL Y-866) (Yeast) (Candida colliculosa)Imported
Taxonomic identifieri1076872 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeTorulaspora
ProteomesiUP000005627 Componenti: Chromosome 3

Structurei

3D structure databases

ProteinModelPortaliG8ZRF1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

InParanoidiG8ZRF1.
KOiK10747.
OrthoDBiEOG7TXKRG.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G8ZRF1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFRVVGRPLV ELLINKGMSS GKKQATLARF FSAVQKDDTK EKVNGDVKII
60 70 80 90 100
ESRDNQDEPV TKKFKSSSPV KLQTSSLSPV KSAGVESGDK PVSPDLYYSK
110 120 130 140 150
VPYSDVCNVF QEIEGTSSRL SIIKICSEFF SRIMKDNPQN LIPTTYLFIN
160 170 180 190 200
RLGPDYEPGL ELGLGEGLLM KTISEACGKS LVQVKNRYRE MGDLGQIALE
210 220 230 240 250
ARNVQPTMFK PKPLTVGEVF ENLRAIAHSQ GKDSQTRKIK LIKRMLTACE
260 270 280 290 300
GVEAKFLIRS LESKLRIGLA EKTVLISLSK ALLTNEGETG KEPSMELVEQ
310 320 330 340 350
AEAKIRDAFC QVPNYEIVIN ACLDYGIMEL DKHCRLRPGI PLKPMLAKPT
360 370 380 390 400
KSITEVLDRF QGQTFTSEYK YDGERAQVHL LEDGTMRIYS RNGENMTERY
410 420 430 440 450
PEISIRDFVA DLEHTKTLIL DCEAVAWDKV QQKILPFQVL STRKRKDVEA
460 470 480 490 500
KDVKVRVCLF AFDIICHNGE RQINKSLRER RELLAQVTKP VAGEFQYAVE
510 520 530 540 550
LTTSSVEELQ KFLDQSVKDS CEGLMVKMLD GPESHYEPSK RSRNWLKLKK
560 570 580 590 600
DYLDGVGDSL DLCVLGAYYG RGKRTGTYGG FLLGCYNQDS GEFETCCKIG
610 620 630 640 650
TGFSDEMLQQ LYERFSKTTL DGPKATYVFD SSAEPDVWFE PTTLFEVLTA
660 670 680 690 700
DLSLSPVYKA GASTYDKGVS LRFPRFVRLR DDKSVEDATS SAQIVELYQD

QSHVA
Length:705
Mass (Da):79,333
Last modified:February 22, 2012 - v1
Checksum:i39C39F49AD819B0B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE616744 Genomic DNA. Translation: CCE91093.1.
RefSeqiXP_003680304.1. XM_003680256.1.

Genome annotation databases

GeneIDi11500428.
KEGGitdl:TDEL_0C02040.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE616744 Genomic DNA. Translation: CCE91093.1.
RefSeqiXP_003680304.1. XM_003680256.1.

3D structure databases

ProteinModelPortaliG8ZRF1.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi11500428.
KEGGitdl:TDEL_0C02040.

Phylogenomic databases

InParanoidiG8ZRF1.
KOiK10747.
OrthoDBiEOG7TXKRG.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Evolutionary erosion of yeast sex chromosomes by mating-type switching accidents."
    Gordon J.L., Armisen D., Proux-Wera E., Oheigeartaigh S.S., Byrne K.P., Wolfe K.H.
    Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 10662 / CBS 1146 / NBRC 0425 / NCYC 2629 / NRRL Y-866Imported.

Entry informationi

Entry nameiG8ZRF1_TORDC
AccessioniPrimary (citable) accession number: G8ZRF1
Entry historyi
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: April 29, 2015
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.