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G8W5A3 (G8W5A3_KLEPH) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 11. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
60 kDa chaperonin RuleBase RU000419 HAMAP-Rule MF_00600
Alternative name(s):
GroEL protein HAMAP-Rule MF_00600
Protein Cpn60 HAMAP-Rule MF_00600
Gene names
Name:groL HAMAP-Rule MF_00600
Synonyms:groEL HAMAP-Rule MF_00600
Ordered Locus Names:KPHS_03800 EMBL AEW59078.1
OrganismKlebsiella pneumoniae subsp. pneumoniae (strain HS11286) [Complete proteome] [HAMAP] EMBL AEW59078.1
Taxonomic identifier1125630 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Klebsiella ›

Protein attributes

Sequence length548 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions By similarity. RuleBase RU000419 HAMAP-Rule MF_00600

Subunit structure

Oligomer of 14 subunits composed of two stacked rings of 7 subunits By similarity. RuleBase RU000419 HAMAP-Rule MF_00600

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00600.

Sequence similarities

Belongs to the chaperonin (HSP60) family. HAMAP-Rule MF_00600 RuleBase RU000418

Ontologies

Keywords
   Cellular componentCytoplasm HAMAP-Rule MF_00600
   LigandATP-binding HAMAP-Rule MF_00600 RuleBase RU003319
Nucleotide-binding
   Molecular functionChaperone HAMAP-Rule MF_00600 RuleBase RU003319
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processprotein refolding

Inferred from electronic annotation. Source: HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
G8W5A3 [UniParc].

Last modified February 22, 2012. Version 1.
Checksum: 0AC83B2B827BBE82

FASTA54857,126
        10         20         30         40         50         60 
MAAKDVKFGN DARVKMLRGV NVLADAVKVT LGPKGRNVVL DKSFGAPTIT KDGVSVAREI 

        70         80         90        100        110        120 
ELEDKFENMG AQMVKEVASK ANDAAGDGTT TATVLAQAIV NEGLKAVAAG MNPMDLKRGI 

       130        140        150        160        170        180 
DKAVLAAVEE LKALSVPCSD SKAIAQVGTI SANSDETVGK LIAEAMDKVG KEGVITVEDG 

       190        200        210        220        230        240 
TGLEDELDVV EGMQFDRGYL SPYFINKPDT GAVELESPFI LLADKKISNI REMLPVLEAV 

       250        260        270        280        290        300 
AKAGKPLVII AEDVEGEALA TLVVNTMRGI VKVAAVKAPG FGDRRKAMLQ DIATLTGGTV 

       310        320        330        340        350        360 
ISEEIGMELE KATLEDLGQA KRVVINKDTT TIIDGVGEES AIQGRVAQIR KQIEEATSDY 

       370        380        390        400        410        420 
DREKLQERVA KLAGGVAVIK VGAATEVEMK EKKARVDDAL HATRAAVEEG VVAGGGVALV 

       430        440        450        460        470        480 
RVAAKLAGLT GQNEDQNVGI KVALRAMEAP LRQIVSNAGE EPSVVANNVK AGDGNYGYNA 

       490        500        510        520        530        540 
ATEEYGNMID FGILDPTKVT RSALQYAASV AGLMITTECM VTDLPKGDAP DLGAAGGMGG 


MGGMGGMM

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References

[1]"Complete genome sequence of Klebsiella pneumoniae subsp. pneumoniae HS11286, a multidrug-resistant strain Isolated from human sputum."
Liu P., Li P., Jiang X., Bi D., Xie Y., Tai C., Deng Z., Rajakumar K., Ou H.Y.
J. Bacteriol. 194:1841-1842(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HS11286 EMBL AEW59078.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP003200 Genomic DNA. Translation: AEW59078.1.
RefSeqYP_005224680.1. NC_016845.1.

3D structure databases

ProteinModelPortalG8W5A3.
SMRG8W5A3. Positions 2-526.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEW59078; AEW59078; KPHS_03800.
GeneID11845367.
KEGGkpm:KPHS_03800.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK04077.

Family and domain databases

HAMAPMF_00600. CH60.
InterProIPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
[Graphical view]
PANTHERPTHR11353. PTHR11353. 1 hit.
PfamPF00118. Cpn60_TCP1. 1 hit.
[Graphical view]
PRINTSPR00298. CHAPERONIN60.
SUPFAMSSF48592. GroEL-ATPase. 1 hit.
TIGRFAMsTIGR02348. GroEL. 1 hit.
PROSITEPS00296. CHAPERONINS_CPN60. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG8W5A3_KLEPH
AccessionPrimary (citable) accession number: G8W5A3
Entry history
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: May 1, 2013
This is version 11 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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