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Protein
Submitted name:

4-aminobutyrate aminotransferase

Gene

KPHS_49790

Organism
Klebsiella pneumoniae subsp. pneumoniae (strain HS11286)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. 4-aminobutyrate transaminase activity Source: InterPro
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. gamma-aminobutyric acid metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseImported, Transferase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciKPNE1125630:GJUV-5065-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
4-aminobutyrate aminotransferaseImported
Gene namesi
Ordered Locus Names:KPHS_49790Imported
OrganismiKlebsiella pneumoniae subsp. pneumoniae (strain HS11286)Imported
Taxonomic identifieri1125630 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
ProteomesiUP000007841: Chromosome

Structurei

3D structure databases

ProteinModelPortaliG8W4V1.
SMRiG8W4V1. Positions 2-420.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

Phylogenomic databases

KOiK00823.
OMAiYHAQYPN.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00700. GABAtrnsam. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G8W4V1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKSSELNQRR QQATPRGVGV MCNYFVEKAE NATLWDIEGN EVIDFAAGIA
60 70 80 90 100
VLNTGHRHPK VVAAVADQLQ AFTHTAYQIV PYESYVSLAE RINDLAPIDG
110 120 130 140 150
PAKTAFFTTG AEAVENAVKI ARAYTGRPGL ITFGGGFHGR TFMTMALTGK
160 170 180 190 200
VAPYKIGFGP FPGSVYHGVY PNAAHGVTTA DALKSLERIF KADIAPDQVA
210 220 230 240 250
AIILEPIQGE GGFNVAPADF MQALRDLCDT HGILLIADEV QTGFARTGKL
260 270 280 290 300
FAMQHYEVKP DLMTMAKSLA GGFPLSGVVG RAEVMDAPAP GGLGGTYAGN
310 320 330 340 350
PLAVAAAHAV LDVIAEEQLC QRAEQLGSHL QEVLNQARAT CPAIVDVRGR
360 370 380 390 400
GSMVAVEFND PQTGEPSPEF TRLVQQKAQE NGLLLLSCGV YGNVIRFLYP
410 420
LTIPDAQFSK ALDILARVLK S
Length:421
Mass (Da):44,926
Last modified:February 22, 2012 - v1
Checksum:i3B1F5D8016FDD5A5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003200 Genomic DNA. Translation: AEW63677.1.
RefSeqiYP_005229279.1. NC_016845.1.

Genome annotation databases

EnsemblBacteriaiAEW63677; AEW63677; KPHS_49790.
GeneIDi11850048.
KEGGikpm:KPHS_49790.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003200 Genomic DNA. Translation: AEW63677.1.
RefSeqiYP_005229279.1. NC_016845.1.

3D structure databases

ProteinModelPortaliG8W4V1.
SMRiG8W4V1. Positions 2-420.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEW63677; AEW63677; KPHS_49790.
GeneIDi11850048.
KEGGikpm:KPHS_49790.

Phylogenomic databases

KOiK00823.
OMAiYHAQYPN.

Enzyme and pathway databases

BioCyciKPNE1125630:GJUV-5065-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00700. GABAtrnsam. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of Klebsiella pneumoniae subsp. pneumoniae HS11286, a multidrug-resistant strain Isolated from human sputum."
    Liu P., Li P., Jiang X., Bi D., Xie Y., Tai C., Deng Z., Rajakumar K., Ou H.Y.
    J. Bacteriol. 194:1841-1842(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HS11286Imported.

Entry informationi

Entry nameiG8W4V1_KLEPH
AccessioniPrimary (citable) accession number: G8W4V1
Entry historyi
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: January 7, 2015
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.