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G8W3Y5 (G8W3Y5_KLEPH) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 8. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595
Short name=PEPC HAMAP-Rule MF_00595
Short name=PEPCase HAMAP-Rule MF_00595
EC=4.1.1.31 HAMAP-Rule MF_00595
Gene names
Name:ppc HAMAP-Rule MF_00595
Ordered Locus Names:KPHS_00980 EMBL AEW58796.1
OrganismKlebsiella pneumoniae subsp. pneumoniae (strain HS11286) [Complete proteome] [HAMAP] EMBL AEW58796.1
Taxonomic identifier1125630 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Klebsiella ›

Protein attributes

Sequence length883 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595 SAAS SAAS022805

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595 SAAS SAAS018129

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00595 SAAS SAAS018129

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00595

Sequence similarities

Belongs to the PEPCase type 1 family. HAMAP-Rule MF_00595

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1381 By similarity HAMAP-Rule MF_00595
Active site5461 By similarity HAMAP-Rule MF_00595

Sequences

Sequence LengthMass (Da)Tools
G8W3Y5 [UniParc].

Last modified February 22, 2012. Version 1.
Checksum: EFD19A5D64473999

FASTA88398,972
        10         20         30         40         50         60 
MNEQYSALRS NVSMLGKVLG DTIKDALGEN ILDRVETIRK LSKSSRAGNE ANRQELLTTL 

        70         80         90        100        110        120 
QNLSNDELLP VARAFSQFLN LANTAEQYHS ISPNGEAASN PEVIARTLRK LKDQPNLNEE 

       130        140        150        160        170        180 
TIKKAVESLS LELVLTAHPT EITRRTLIHK MVEVNNCLKQ LDNKDIADYE HHQLMRRLRQ 

       190        200        210        220        230        240 
LIAQSWHTDE IRKHRPSPVD EAKWGFAVVE NSLWEGVPNY LRELNEQLEA NLGYQLPVDF 

       250        260        270        280        290        300 
VPVRFTSWMG GDRDGNPNVT ADITRHVLLL SRWKATDLFL KDVQVLISEL SMVECTDELR 

       310        320        330        340        350        360 
ALAGAEGAQE PYRYLMKKLR SQLMETQAWL EARLKGQKLP KPAGLITQNE QLWEPLYACY 

       370        380        390        400        410        420 
KSLQACGMGI IANGELLDTL RRVKSFGVPL VRIDIRQEST RHTEALGEMT RYLGIGDYES 

       430        440        450        460        470        480 
WSEADKQAFL IRELNSKRPL LPRQWEPSEE TREVLDTCKV IAEAPRGSIA AYVISMAKTP 

       490        500        510        520        530        540 
SDVLAVHLLL KEAGIGFALP VAPLFETLDD LNNANDVMTQ LLNIDWYRGF IQGKQMVMIG 

       550        560        570        580        590        600 
YSDSAKDAGV MAASWAQYQA QDALIKTCEK AGIELTLFHG RGGSIGRGGA PAHAALLSQP 

       610        620        630        640        650        660 
PGSLKGGLRV TEQGEMIRFK YGLPEVTISS LSLYTSAILE ANLLPPPEPK AEWRDIMAEL 

       670        680        690        700        710        720 
SDVSCKMYRG YVRENKDFVP YFRSATPEQE LGKLPLGSRP AKRRPTGGVE SLRAIPWIFA 

       730        740        750        760        770        780 
WTQNRLMLPA WLGAGAALQK VVEGGKQSEL EAMCRDWPFF STRLGMLEMV YSKADLWLAE 

       790        800        810        820        830        840 
YYDQRLVKPE LWALGSELRK LLAADINVVL AIANDSHLMA DLPWIAESIQ LRNIYTDPLN 

       850        860        870        880 
VLQAELLHRS RQAEEEGKDP DPRVEQALMV TIAGVAAGMR NTG

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References

[1]"Complete genome sequence of Klebsiella pneumoniae subsp. pneumoniae HS11286, a multidrug-resistant strain Isolated from human sputum."
Liu P., Li P., Jiang X., Bi D., Xie Y., Tai C., Deng Z., Rajakumar K., Ou H.Y.
J. Bacteriol. 194:1841-1842(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HS11286 EMBL AEW58796.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP003200 Genomic DNA. Translation: AEW58796.1.
RefSeqYP_005224398.1. NC_016845.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEW58796; AEW58796; KPHS_00980.
GeneID11845076.
KEGGkpm:KPHS_00980.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01595.

Family and domain databases

HAMAPMF_00595. PEPcase_type1.
InterProIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase.
[Graphical view]
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSPR00150. PEPCARBXLASE.
SUPFAMSSF51621. Pyrv/PenolPyrv_Kinase_cat. 1 hit.
PROSITEPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG8W3Y5_KLEPH
AccessionPrimary (citable) accession number: G8W3Y5
Entry history
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: April 3, 2013
This is version 8 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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