G8VWW7 (G8VWW7_KLEPH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrB HAMAP-Rule MF_01400
EC=1.8.4.12 HAMAP-Rule MF_01400

Alternative name(s):
Peptide-methionine (R)-S-oxide reductase HAMAP-Rule MF_01400

Gene names

Name:	msrB HAMAP-Rule MF_01400
Ordered Locus Names:	KPHS_20810 EMBL AEW60779.1

Organism

Klebsiella pneumoniae subsp. pneumoniae (strain HS11286) [Complete proteome] [HAMAP] EMBL AEW60779.1

Taxonomic identifier

1125630 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Klebsiella › Klebsiella pneumoniae › Klebsiella pneumoniae subsp. pneumoniae

Protein attributes

Sequence length	137 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin. HAMAP-Rule MF_01400
Cofactor	Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein By similarity. HAMAP-Rule MF_01400
Sequence similarities	Belongs to the MsrB Met sulfoxide reductase family. HAMAP-Rule MF_01400

Ontologies

Keywords
Ligand	Metal-binding HAMAP-Rule MF_01400 SAAS SAAS011057 Zinc HAMAP-Rule MF_01400 SAAS SAAS011057
Molecular function	Oxidoreductase HAMAP-Rule MF_01400 SAAS SAAS011057
Technical term	Complete proteome
Gene Ontology (GO)
Molecular_function	peptide-methionine (R)-S-oxide reductase activity Inferred from electronic annotation. Source: EC peptide-methionine (S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP zinc ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	118	1	Nucleophile By similarity HAMAP-Rule MF_01400
	Metal binding	46	1	Zinc By similarity HAMAP-Rule MF_01400
	Metal binding	49	1	Zinc By similarity HAMAP-Rule MF_01400
	Metal binding	95	1	Zinc By similarity HAMAP-Rule MF_01400
	Metal binding	98	1	Zinc By similarity HAMAP-Rule MF_01400

Sequences

	Sequence		Length	Mass (Da)
	G8VWW7 [UniParc]. Last modified February 22, 2012. Version 1. Checksum: 1D6ECACED2F665CC	FASTA	137	15,292
	10 20 30 40 50 60 MANKPTPEEL KNGLSEMQFY VTQHHGTEPP FTGRLLHNKK NGVYHCLVCD APLFNSQTKY 70 80 90 100 110 120 DSGCGWPSFY EPVSAEAIRY LTDNSHGMQR IEIRCGNCDA HLGHVFPDGP QPTGERYCVN 130 SASLSFTDEQ NGEQIKG

References

[1]

"Complete genome sequence of Klebsiella pneumoniae subsp. pneumoniae HS11286, a multidrug-resistant strain Isolated from human sputum." Liu P., Li P., Jiang X., Bi D., Xie Y., Tai C., Deng Z., Rajakumar K., Ou H.Y. J. Bacteriol. 194:1841-1842(2012) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HS11286 EMBL AEW60779.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP003200 Genomic DNA. Translation: AEW60779.1.
RefSeq	YP_005226381.1. NC_016845.1.
3D structure databases
ProteinModelPortal	G8VWW7.
SMR	G8VWW7. Positions 5-128.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AEW60779; AEW60779; KPHS_20810.
GeneID	11847099.
KEGG	kpm:KPHS_20810.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K07305.
Family and domain databases
Gene3D	2.170.150.20. 1 hit.
HAMAP	MF_01400. MsrB.
InterPro	IPR002579. Met_Sox_Rdtase_MsrB. IPR011057. Mss4-like. [Graphical view]
Pfam	PF01641. SelR. 1 hit. [Graphical view]
SUPFAM	SSF51316. Mss4_like. 1 hit.
TIGRFAMs	TIGR00357. TIGR00357. 1 hit.
ProtoNet	Search...

Entry information

Entry name

G8VWW7_KLEPH

Accession

Primary (citable) accession number: G8VWW7

Entry history

Integrated into UniProtKB/TrEMBL:	February 22, 2012
Last sequence update:	February 22, 2012
Last modified:	April 3, 2013
This is version 12 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)