G8VNE2 (G8VNE2_PROAA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Alpha-ketoglutarate decarboxylase EMBL AEW83835.1
EC=4.1.1.71 EMBL AEW83835.1

Gene names

Name:	kgd EMBL AEW83835.1
ORF Names:	TIA2EST36_06245 EMBL AEW83835.1

Organism

Propionibacterium acnes TypeIA2 P.acn31 EMBL AEW83835.1

Taxonomic identifier

1114969 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Propionibacterineae › Propionibacteriaceae › Propionibacterium › Propionibacterium acnes

Protein attributes

Sequence length	1235 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Lyase EMBL AEW83835.1
Gene Ontology (GO)
Biological_process	tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Molecular_function	2-oxoglutarate decarboxylase activity Inferred from electronic annotation. Source: EC oxoglutarate dehydrogenase (succinyl-transferring) activity Inferred from electronic annotation. Source: InterPro thiamine pyrophosphate binding Inferred from electronic annotation. Source: InterPro transferase activity, transferring acyl groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	G8VNE2 [UniParc]. Last modified February 22, 2012. Version 1. Checksum: DA916B92886E8859	FASTA	1,235	136,717
	10 20 30 40 50 60 MSPAPHDKSN NSPDFGANDW LIEEMRDQYQ SDPNSVDPAW ATFFRKEAVE STDSVTKSAA 70 80 90 100 110 120 KDVPGASAPK PATKPQPVPA AKPAPITAPK PQKQPPRPPM SADAPRHSAK LETVEPTVTK 130 140 150 160 170 180 MKGAPMRTAK NMDQSLTMPT ATTVRDVPMQ LVIEQRTMIN SFLKKAKGGK VSFTHILAYA 190 200 210 220 230 240 MVQALKTVSA MNNAYAEIDG KPHLIENHQI NLGMAIDVIA SDGSRKLVVP AIKGAEQMDF 250 260 270 280 290 300 LDFWRAYEEI VRKGRTNELT VDDFKGVTAS LTNPGGFGTN HSIARLMPGQ GMILGVGSID 310 320 330 340 350 360 YPAAYQGNSP TRIAELGISK VTTLTSTYDH RIIQGAQSGE FLRRMHQLLL GADRFYEDIF 370 380 390 400 410 420 ESLRIPYAPV QWASDRLANR ADQVGKQARV IELIDAWRRF GHLSADLDPI EYRPRFHRDL 430 440 450 460 470 480 MLNSHGLTLW DFDRTFPIAN FAGQRRATMS LREILTILRD SYASKMGIEY MHIADYEQRK 490 500 510 520 530 540 WFQDRFEKEH QPLSRKMHLQ ILDQLNEAEI FETFLQTKFV GQKRFSLEGG ESAIVLLAAL 550 560 570 580 590 600 CNRAADDGLN EVCIGMPHRG RLNVLANIIG KSYGQIFREF EGNAEPVNSQ GSGDVKYHLG 610 620 630 640 650 660 DEGQFTAASG NTIKASVAAN PSHLEAVDPV LEGICRAKLD ALGNPEGFPV LPILMHGDAA 670 680 690 700 710 720 FAGQGVVYET LQMSQLGGYR TGGTIHVIVN NQVGFTTSPR DGRSSTYCTD VAKAVGAPVL 730 740 750 760 770 780 HVNGDDPASV VHAARIAYEY RQTFHRDVVV DVVCYRRRGH NEGDDPSFTQ PHMYGLIAEK 790 800 810 820 830 840 RSTRKLYTES LIGRGDITTE DAEAVMTKFR SRLETVFKEV REATSTPEPY SGVPDYPVKH 850 860 870 880 890 900 SGLHQTKVEP DTMEAVARAH ENLPESFNAH PKVAPQMTRR AKHIREGGID WATGEMIALG 910 920 930 940 950 960 SLLRDGVHVR LAGQDSRRGT FSQRFAALVD HETGEFYVPV NHLGGEQAHL DVFDSPLNEY 970 980 990 1000 1010 1020 AAMGFEYGYS VARPDSLVLW EAQFGDFTNG AQTIIDEFIA SAGSKWGQKS GVVLLLPHGY 1030 1040 1050 1060 1070 1080 EGQGPDHSSA RLERFLNLCS EDALAVCQPS TPASYSHLLR QHAYVNMHRP VVIATPKSML 1090 1100 1110 1120 1130 1140 RNKMATSDPE DFTTGRWRPV LPDPSITDPT AVTRIILCSG KARWELVKQR KATSLDGQLA 1150 1160 1170 1180 1190 1200 IIPMERLYPL PVDELAEVLA PYTNVTDVRW VQEEPENQGA WYYMLTHLPQ AMSEKLPGFF 1210 1220 1230 DGLVGITRPP SSAPSVGQHS VHIREEQELL EKAMA

References

[1]

"Complete Genome Sequences of Three Propionibacterium acnes Isolates from the Type IA2 Cluster." Voros A., Horvath B., Hunyadkurti J., McDowell A., Barnard E., Patrick S., Nagy I. J. Bacteriol. 194:1621-1622(2012) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: P.acn31 EMBL AEW83835.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP003197 Genomic DNA. Translation: AEW83835.1.
RefSeq	YP_004944518.1. NC_016511.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AEW83835; AEW83835; TIA2EST36_06245.
GeneID	11480493.
KEGG	pax:TIA2EST36_06245.
Phylogenomic databases
KO	K00164.
Family and domain databases
Gene3D	3.30.559.10. 1 hit.
InterPro	IPR001078. 2-oxoacid_DH_actylTfrase. IPR011603. 2oxoglutarate_DH_E1. IPR023213. CAT-like_dom. IPR001017. DH_E1. IPR005475. Transketolase-like_Pyr-bd. [Graphical view]
PANTHER	PTHR23152. PTHR23152. 1 hit.
Pfam	PF00198. 2-oxoacid_dh. 1 hit. PF00676. E1_dh. 1 hit. PF02779. Transket_pyr. 1 hit. [Graphical view]
PIRSF	PIRSF000157. Oxoglu_dh_E1. 1 hit.
SMART	SM00861. Transket_pyr. 1 hit. [Graphical view]
TIGRFAMs	TIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNet	Search...

Entry information

Entry name

G8VNE2_PROAA

Accession

Primary (citable) accession number: G8VNE2

Entry history

Integrated into UniProtKB/TrEMBL:	February 22, 2012
Last sequence update:	February 22, 2012
Last modified:	April 3, 2013
This is version 9 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)