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G8VNE2

- G8VNE2_PROAA

UniProt

G8VNE2 - G8VNE2_PROAA

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Protein
Submitted name:

Alpha-ketoglutarate decarboxylase

Gene
kgd, TIA2EST36_06245
Organism
Propionibacterium acnes TypeIA2 P.acn31
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. 2-oxoglutarate decarboxylase activity Source: UniProtKB-EC
  2. oxoglutarate dehydrogenase (succinyl-transferring) activity Source: InterPro
  3. thiamine pyrophosphate binding Source: InterPro
  4. transferase activity, transferring acyl groups Source: InterPro

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseImported

Enzyme and pathway databases

BioCyciPACN1114969:GJUU-1244-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha-ketoglutarate decarboxylaseImported (EC:4.1.1.71Imported)
Gene namesi
Name:kgdImported
ORF Names:TIA2EST36_06245Imported
OrganismiPropionibacterium acnes TypeIA2 P.acn31Imported
Taxonomic identifieri1114969 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesPropionibacterineaePropionibacteriaceaePropionibacterium
ProteomesiUP000007852: Chromosome

Family & Domainsi

Phylogenomic databases

KOiK00164.

Family and domain databases

Gene3Di3.30.559.10. 1 hit.
3.40.50.970. 2 hits.
InterProiIPR001078. 2-oxoacid_DH_actylTfrase.
IPR011603. 2oxoglutarate_DH_E1.
IPR023213. CAT-like_dom.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00198. 2-oxoacid_dh. 1 hit.
PF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.

Sequencei

Sequence statusi: Complete.

G8VNE2-1 [UniParc]FASTAAdd to Basket

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MSPAPHDKSN NSPDFGANDW LIEEMRDQYQ SDPNSVDPAW ATFFRKEAVE     50
STDSVTKSAA KDVPGASAPK PATKPQPVPA AKPAPITAPK PQKQPPRPPM 100
SADAPRHSAK LETVEPTVTK MKGAPMRTAK NMDQSLTMPT ATTVRDVPMQ 150
LVIEQRTMIN SFLKKAKGGK VSFTHILAYA MVQALKTVSA MNNAYAEIDG 200
KPHLIENHQI NLGMAIDVIA SDGSRKLVVP AIKGAEQMDF LDFWRAYEEI 250
VRKGRTNELT VDDFKGVTAS LTNPGGFGTN HSIARLMPGQ GMILGVGSID 300
YPAAYQGNSP TRIAELGISK VTTLTSTYDH RIIQGAQSGE FLRRMHQLLL 350
GADRFYEDIF ESLRIPYAPV QWASDRLANR ADQVGKQARV IELIDAWRRF 400
GHLSADLDPI EYRPRFHRDL MLNSHGLTLW DFDRTFPIAN FAGQRRATMS 450
LREILTILRD SYASKMGIEY MHIADYEQRK WFQDRFEKEH QPLSRKMHLQ 500
ILDQLNEAEI FETFLQTKFV GQKRFSLEGG ESAIVLLAAL CNRAADDGLN 550
EVCIGMPHRG RLNVLANIIG KSYGQIFREF EGNAEPVNSQ GSGDVKYHLG 600
DEGQFTAASG NTIKASVAAN PSHLEAVDPV LEGICRAKLD ALGNPEGFPV 650
LPILMHGDAA FAGQGVVYET LQMSQLGGYR TGGTIHVIVN NQVGFTTSPR 700
DGRSSTYCTD VAKAVGAPVL HVNGDDPASV VHAARIAYEY RQTFHRDVVV 750
DVVCYRRRGH NEGDDPSFTQ PHMYGLIAEK RSTRKLYTES LIGRGDITTE 800
DAEAVMTKFR SRLETVFKEV REATSTPEPY SGVPDYPVKH SGLHQTKVEP 850
DTMEAVARAH ENLPESFNAH PKVAPQMTRR AKHIREGGID WATGEMIALG 900
SLLRDGVHVR LAGQDSRRGT FSQRFAALVD HETGEFYVPV NHLGGEQAHL 950
DVFDSPLNEY AAMGFEYGYS VARPDSLVLW EAQFGDFTNG AQTIIDEFIA 1000
SAGSKWGQKS GVVLLLPHGY EGQGPDHSSA RLERFLNLCS EDALAVCQPS 1050
TPASYSHLLR QHAYVNMHRP VVIATPKSML RNKMATSDPE DFTTGRWRPV 1100
LPDPSITDPT AVTRIILCSG KARWELVKQR KATSLDGQLA IIPMERLYPL 1150
PVDELAEVLA PYTNVTDVRW VQEEPENQGA WYYMLTHLPQ AMSEKLPGFF 1200
DGLVGITRPP SSAPSVGQHS VHIREEQELL EKAMA 1235
Length:1,235
Mass (Da):136,717
Last modified:February 22, 2012 - v1
Checksum:iDA916B92886E8859
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003197 Genomic DNA. Translation: AEW83835.1.
RefSeqiWP_002517855.1. NC_016511.1.
YP_004944518.1. NC_016511.1.

Genome annotation databases

EnsemblBacteriaiAEW83835; AEW83835; TIA2EST36_06245.
GeneIDi11480493.
KEGGipax:TIA2EST36_06245.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003197 Genomic DNA. Translation: AEW83835.1 .
RefSeqi WP_002517855.1. NC_016511.1.
YP_004944518.1. NC_016511.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEW83835 ; AEW83835 ; TIA2EST36_06245 .
GeneIDi 11480493.
KEGGi pax:TIA2EST36_06245.

Phylogenomic databases

KOi K00164.

Enzyme and pathway databases

BioCyci PACN1114969:GJUU-1244-MONOMER.

Family and domain databases

Gene3Di 3.30.559.10. 1 hit.
3.40.50.970. 2 hits.
InterProi IPR001078. 2-oxoacid_DH_actylTfrase.
IPR011603. 2oxoglutarate_DH_E1.
IPR023213. CAT-like_dom.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view ]
PANTHERi PTHR23152. PTHR23152. 1 hit.
Pfami PF00198. 2-oxoacid_dh. 1 hit.
PF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view ]
PIRSFi PIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTi SM00861. Transket_pyr. 1 hit.
[Graphical view ]
SUPFAMi SSF52518. SSF52518. 2 hits.
TIGRFAMsi TIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete Genome Sequences of Three Propionibacterium acnes Isolates from the Type IA2 Cluster."
    Voros A., Horvath B., Hunyadkurti J., McDowell A., Barnard E., Patrick S., Nagy I.
    J. Bacteriol. 194:1621-1622(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: P.acn31Imported.

Entry informationi

Entry nameiG8VNE2_PROAA
AccessioniPrimary (citable) accession number: G8VNE2
Entry historyi
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: September 3, 2014
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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