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G8VM15 (G8VM15_PROAA) Unreviewed, UniProtKB/TrEMBL

Last modified January 22, 2014. Version 12. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
Gene names
ORF Names:TIA2EST36_08520 EMBL AEW84274.1
OrganismPropionibacterium acnes TypeIA2 P.acn31 [Complete proteome] EMBL AEW84274.1
Taxonomic identifier1114969 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesPropionibacterineaePropionibacteriaceaePropionibacterium

Protein attributes

Sequence length734 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. PIRSR PIRSR009407-3

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region130 – 1378Substrate binding By similarity PIRSR PIRSR009407-2

Sites

Metal binding3471Magnesium or manganese By similarity
Metal binding5421Magnesium or manganese By similarity
Metal binding5461Magnesium or manganese By similarity
Binding site1431Substrate By similarity PIRSR PIRSR009407-2
Binding site5411Substrate By similarity PIRSR PIRSR009407-2
Site2521Critical for catalysis By similarity PIRSR PIRSR009407-1
Site4171Critical for catalysis By similarity PIRSR PIRSR009407-1

Sequences

Sequence LengthMass (Da)Tools
G8VM15 [UniParc].

Last modified February 22, 2012. Version 1.
Checksum: 74AD29981DA085D6

FASTA73479,967
        10         20         30         40         50         60 
MPTIVWTKID EAPALASYSL LPIVEGFLDG SGIDITTSDI SLAGRILAQF PDRLNEDQKV 

        70         80         90        100        110        120 
ADHLAELGEL TGSPDANIIK LPNISASVPQ LKAAIAELQS QGYELPDFPD KPSTDEEREI 

       130        140        150        160        170        180 
AARYATVLGS AVNPVLRQGN SDRRAPTAVK AYAKAHPHRM GQWTDQVKAR VAHMDHGDFF 

       190        200        210        220        230        240 
DHEESFVSRG QDLDVVLIGT DGSETTLVSG IKTLDGEIVD ATFMSVDALD EFYASSLAQA 

       250        260        270        280        290        300 
NEEDLLWSVH LKATMMKVSD PVLFGHAVRT FLVDVFDKYG DDLNSVGVNP DLGLGDLYTR 

       310        320        330        340        350        360 
LEKLPAERAT AIKAAIDSAF AARPALAMVD SDNGITNLHA GNLVIIDASM PTVVRDSGCM 

       370        380        390        400        410        420 
WNAEGKRQET LACIPDRSYA TMYAAIMDDC REHGALDPAT MGDVPNVGLM AQKAEEYGSH 

       430        440        450        460        470        480 
PTTFIVPHDG RVEVRCGDEV LTNQQVEAGD VWRMSRVRDI PVRDWVRLAI ERARITNTPA 

       490        500        510        520        530        540 
VFWLDKNRAH DARVIEKVKA YLPEHEGLDI RILAPADAMK FTLARIRRGE DTISVTGNVL 

       550        560        570        580        590        600 
RDYLTDVFPI LEIGTSAKML SVVPLLAGGG LFETGAGGSA PKHVAQFVAE DYLRWDSLGE 

       610        620        630        640        650        660 
FCALGACLEH IDQTSEGTKA GILAATLDKA IGAFLENDRS PARKLGQSDN RGSHYWLARY 

       670        680        690        700        710        720 
WASELAAQHD DAELADRFSD VATELAARED QILKELNGVQ GSPVDMGGYY HPDEELVAEA 

       730 
MRPSTTFNAI IESL 

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References

[1]"Complete Genome Sequences of Three Propionibacterium acnes Isolates from the Type IA2 Cluster."
Voros A., Horvath B., Hunyadkurti J., McDowell A., Barnard E., Patrick S., Nagy I.
J. Bacteriol. 194:1621-1622(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: P.acn31 EMBL AEW84274.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003197 Genomic DNA. Translation: AEW84274.1.
RefSeqYP_004944957.1. NC_016511.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEW84274; AEW84274; TIA2EST36_08520.
GeneID11481176.
KEGGpax:TIA2EST36_08520.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00031.

Enzyme and pathway databases

BioCycPACN1114969:GJUU-1700-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 3 hits.
InterProIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamPF03971. IDH. 1 hit.
[Graphical view]
PIRSFPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsTIGR00178. monomer_idh. 1 hit.
ProtoNetSearch...

Entry information

Entry nameG8VM15_PROAA
AccessionPrimary (citable) accession number: G8VM15
Entry history
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: January 22, 2014
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)