Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

G8VL29

- G8VL29_PROAA

UniProt

G8VL29 - G8VL29_PROAA

Protein

Thymidine kinase

Gene

tdk

Organism
Propionibacterium acnes TypeIA2 P.acn31
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 16 (01 Oct 2014)
      Sequence version 1 (22 Feb 2012)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei87 – 871Proton acceptorUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi9 – 168ATPUniRule annotation
    Nucleotide bindingi86 – 894ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. thymidine kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    KinaseUniRule annotationSAAS annotationImported, Transferase

    Keywords - Biological processi

    DNA synthesisUniRule annotationSAAS annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciPACN1114969:GJUU-1029-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
    Gene namesi
    Name:tdkUniRule annotation
    ORF Names:TIA2EST36_05190Imported
    OrganismiPropionibacterium acnes TypeIA2 P.acn31Imported
    Taxonomic identifieri1114969 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesPropionibacterineaePropionibacteriaceaePropionibacterium
    ProteomesiUP000007852: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliG8VL29.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the thymidine kinase family.UniRule annotation

    Phylogenomic databases

    KOiK00857.

    Family and domain databases

    HAMAPiMF_00124. Thymidine_kinase.
    InterProiIPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020634. Thymidine_kinase_subgr.
    [Graphical view]
    PfamiPF00265. TK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF035805. TK_cell. 1 hit.
    SUPFAMiSSF52540. SSF52540. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    G8VL29-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAELVFHTGP MDSGKSTLAL QMDHAQSAHD RQGVRYAMHD RSGGARITSR    50
    IGLSVEAVEV TDSLDLYQDI VSRLSRGGRI DYLICDEAQF YRTKQIDQLA 100
    RVVDDLDIDV YCFGILADFR TELFPGSKRL VELADRVVEP PVSPLCWCGR 150
    PATHNARIVD GKLVREGDQV GVGDIGGGSE IHYEVLCRRH HRQGITGEIS 200
    RATLSEQTLP FDGSRS 216
    Length:216
    Mass (Da):23,926
    Last modified:February 22, 2012 - v1
    Checksum:iF6055E1F110118C5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003197 Genomic DNA. Translation: AEW83626.1.
    RefSeqiYP_004944309.1. NC_016511.1.

    Genome annotation databases

    EnsemblBacteriaiAEW83626; AEW83626; TIA2EST36_05190.
    GeneIDi11480278.
    KEGGipax:TIA2EST36_05190.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003197 Genomic DNA. Translation: AEW83626.1 .
    RefSeqi YP_004944309.1. NC_016511.1.

    3D structure databases

    ProteinModelPortali G8VL29.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEW83626 ; AEW83626 ; TIA2EST36_05190 .
    GeneIDi 11480278.
    KEGGi pax:TIA2EST36_05190.

    Phylogenomic databases

    KOi K00857.

    Enzyme and pathway databases

    BioCyci PACN1114969:GJUU-1029-MONOMER.

    Family and domain databases

    HAMAPi MF_00124. Thymidine_kinase.
    InterProi IPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020634. Thymidine_kinase_subgr.
    [Graphical view ]
    Pfami PF00265. TK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF035805. TK_cell. 1 hit.
    SUPFAMi SSF52540. SSF52540. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete Genome Sequences of Three Propionibacterium acnes Isolates from the Type IA2 Cluster."
      Voros A., Horvath B., Hunyadkurti J., McDowell A., Barnard E., Patrick S., Nagy I.
      J. Bacteriol. 194:1621-1622(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: P.acn31Imported.

    Entry informationi

    Entry nameiG8VL29_PROAA
    AccessioniPrimary (citable) accession number: G8VL29
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 22, 2012
    Last sequence update: February 22, 2012
    Last modified: October 1, 2014
    This is version 16 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3