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G8U432 (G8U432_BACCE) Unreviewed, UniProtKB/TrEMBL

Last modified January 22, 2014. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446

EC=1.1.1.42 RuleBase RU004446
Gene names
ORF Names:bcf_23005 EMBL AEW57720.1
OrganismBacillus cereus F837/76 [Complete proteome] EMBL AEW57720.1
Taxonomic identifier347495 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group

Protein attributes

Sequence length430 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity.

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
G8U432 [UniParc].

Last modified February 22, 2012. Version 1.
Checksum: 2238E99660A705F3

FASTA43046,973
        10         20         30         40         50         60 
MTTGEKITVT NGVMNVPNNP IIPFIEGDGI GPDIWAAASR VLEAAVEKAY DGEKKIVWKE 

        70         80         90        100        110        120 
VLAGEKAFNQ TGEWLPEETL NLIREYLIAI KGPLTTPVGG GIRSLNVALR QELDLYVCLR 

       130        140        150        160        170        180 
PVRYFEGVPS PVKRPEDTDM VIFRENTEDI YAGIEYAQGS PEAEKVLAFL KEAMGVNKIR 

       190        200        210        220        230        240 
FPETSGIGIK PISEEGTKRL VRAAIQYAIN EKRSSVTLVH KGNIMKFTEG AFKNWGYEVA 

       250        260        270        280        290        300 
EQEFGDKVFT WAEYDRIVEK DGKDAANKAM ADAEVAGKII VKDSIADIFL QQILTRPREF 

       310        320        330        340        350        360 
DVVATMNLNG DYISDALAAQ VGGIGIAPGA NINYVTGHAI FEATHGTAPK YAGLDKVNPS 

       370        380        390        400        410        420 
SVLLSGVLLL EHLGWNEAAK LVTASVEKTI ASKVVTYDFA RLMEGATEVK CSEFANELIK 

       430 
NMDVAIIKNA 

« Hide

References

[1]"Complete Genome Sequence of the Highly Hemolytic Strain Bacillus cereus F837/76."
Auger S., Galleron N., Segurens B., Dossat C., Bolotin A., Wincker P., Sorokin A.
J. Bacteriol. 194:1630-1630(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: F837/76 EMBL AEW57720.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003187 Genomic DNA. Translation: AEW57720.1.
RefSeqYP_005121233.1. NC_016779.1.

3D structure databases

ProteinModelPortalG8U432.
SMRG8U432. Positions 1-423.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEW57720; AEW57720; bcf_23005.
GeneID11678188.
KEGGbcf:bcf_23005.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00031.

Enzyme and pathway databases

BioCycBCER347495:GHGC-4601-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG8U432_BACCE
AccessionPrimary (citable) accession number: G8U432
Entry history
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: January 22, 2014
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)