Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

G8U432

- G8U432_BACCE

UniProt

G8U432 - G8U432_BACCE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Isocitrate dehydrogenase [NADP]

Gene

bcf_23005

Organism
Bacillus cereus F837/76
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.UniRule annotation

Cofactori

Note: Binds 1 magnesium or manganese ion per subunit.UniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. magnesium ion binding Source: InterPro
  3. NAD binding Source: InterPro

GO - Biological processi

  1. glyoxylate cycle Source: UniProtKB-KW
  2. tricarboxylic acid cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Keywords - Biological processi

Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

Keywords - Ligandi

ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

Enzyme and pathway databases

BioCyciBCER347495:GHGC-4601-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
Gene namesi
ORF Names:bcf_23005Imported
OrganismiBacillus cereus F837/76Imported
Taxonomic identifieri347495 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
ProteomesiUP000007854: Chromosome

Structurei

3D structure databases

ProteinModelPortaliG8U432.
SMRiG8U432. Positions 1-423.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

Phylogenomic databases

KOiK00031.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G8U432-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTTGEKITVT NGVMNVPNNP IIPFIEGDGI GPDIWAAASR VLEAAVEKAY
60 70 80 90 100
DGEKKIVWKE VLAGEKAFNQ TGEWLPEETL NLIREYLIAI KGPLTTPVGG
110 120 130 140 150
GIRSLNVALR QELDLYVCLR PVRYFEGVPS PVKRPEDTDM VIFRENTEDI
160 170 180 190 200
YAGIEYAQGS PEAEKVLAFL KEAMGVNKIR FPETSGIGIK PISEEGTKRL
210 220 230 240 250
VRAAIQYAIN EKRSSVTLVH KGNIMKFTEG AFKNWGYEVA EQEFGDKVFT
260 270 280 290 300
WAEYDRIVEK DGKDAANKAM ADAEVAGKII VKDSIADIFL QQILTRPREF
310 320 330 340 350
DVVATMNLNG DYISDALAAQ VGGIGIAPGA NINYVTGHAI FEATHGTAPK
360 370 380 390 400
YAGLDKVNPS SVLLSGVLLL EHLGWNEAAK LVTASVEKTI ASKVVTYDFA
410 420 430
RLMEGATEVK CSEFANELIK NMDVAIIKNA
Length:430
Mass (Da):46,973
Last modified:February 22, 2012 - v1
Checksum:i2238E99660A705F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003187 Genomic DNA. Translation: AEW57720.1.
RefSeqiYP_005121233.1. NC_016779.1.

Genome annotation databases

EnsemblBacteriaiAEW57720; AEW57720; bcf_23005.
GeneIDi11678188.
KEGGibcf:bcf_23005.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003187 Genomic DNA. Translation: AEW57720.1 .
RefSeqi YP_005121233.1. NC_016779.1.

3D structure databases

ProteinModelPortali G8U432.
SMRi G8U432. Positions 1-423.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEW57720 ; AEW57720 ; bcf_23005 .
GeneIDi 11678188.
KEGGi bcf:bcf_23005.

Phylogenomic databases

KOi K00031.

Enzyme and pathway databases

BioCyci BCER347495:GHGC-4601-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 1 hit.
InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
PANTHERi PTHR11835. PTHR11835. 1 hit.
Pfami PF00180. Iso_dh. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
PROSITEi PS00470. IDH_IMDH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete Genome Sequence of the Highly Hemolytic Strain Bacillus cereus F837/76."
    Auger S., Galleron N., Segurens B., Dossat C., Bolotin A., Wincker P., Sorokin A.
    J. Bacteriol. 194:1630-1630(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: F837/76Imported.

Entry informationi

Entry nameiG8U432_BACCE
AccessioniPrimary (citable) accession number: G8U432
Entry historyi
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: November 26, 2014
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3