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G8T9S6

- G8T9S6_NIAKG

UniProt

G8T9S6 - G8T9S6_NIAKG

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Protein

Thymidine kinase

Gene
tdk, Niako_5031
Organism
Niastella koreensis (strain DSM 17620 / KACC 11465 / GR20-10)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei93 – 931Proton acceptor By similarityUniRule annotation
Metal bindingi149 – 1491Zinc By similarityUniRule annotation
Metal bindingi152 – 1521Zinc By similarityUniRule annotation
Metal bindingi181 – 1811Zinc By similarityUniRule annotation
Metal bindingi184 – 1841Zinc By similarityUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi20 – 278ATP By similarityUniRule annotation
Nucleotide bindingi92 – 954ATP By similarityUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. thymidine kinase activity Source: UniProtKB-HAMAP
  3. zinc ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotationsImported, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotationSAAS annotations

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, Metal-bindingUniRule annotationSAAS annotations, Nucleotide-binding, ZincUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciNKOR700598:GHC3-5082-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotation
Ordered Locus Names:Niako_5031Imported
OrganismiNiastella koreensis (strain DSM 17620 / KACC 11465 / GR20-10)Imported
Taxonomic identifieri700598 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesSphingobacteriiaSphingobacterialesChitinophagaceaeNiastella
ProteomesiUP000005438: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotationSAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotations

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotationSAAS annotations

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

KOiK00857.
OMAiQAICLSC.

Family and domain databases

HAMAPiMF_00124. Thymidine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G8T9S6-1 [UniParc]FASTAAdd to Basket

« Hide

MFIEPNISGE RRGSIEVICG SMFSGKTEEL IRRLKRAKIA NLRVEIFKPK    50
IDVRYDVHNI VSHDENAILS TPIDNSQTIL LLHNEADVIG IDEAQFFDDQ 100
LPDVCDQLAL RGHRVIVAGL DMDYTGKPFG QIPFLLSKAD YITKLHAICV 150
KCGHIANYSF RKKADKTQVL LGEKDVYEPR CRKCYYEGAV ENG 193
Length:193
Mass (Da):21,842
Last modified:February 22, 2012 - v1
Checksum:iB48AF196D0EAD18B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003178 Genomic DNA. Translation: AEW01270.1.
RefSeqiYP_005010673.1. NC_016609.1.

Genome annotation databases

EnsemblBacteriaiAEW01270; AEW01270; Niako_5031.
GeneIDi11650980.
KEGGinko:Niako_5031.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003178 Genomic DNA. Translation: AEW01270.1 .
RefSeqi YP_005010673.1. NC_016609.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEW01270 ; AEW01270 ; Niako_5031 .
GeneIDi 11650980.
KEGGi nko:Niako_5031.

Phylogenomic databases

KOi K00857.
OMAi QAICLSC.

Enzyme and pathway databases

BioCyci NKOR700598:GHC3-5082-MONOMER.

Family and domain databases

HAMAPi MF_00124. Thymidine_kinase.
InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view ]
PANTHERi PTHR11441. PTHR11441. 1 hit.
Pfami PF00265. TK. 1 hit.
[Graphical view ]
PIRSFi PIRSF035805. TK_cell. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
PROSITEi PS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 17620 / KACC 11465 / GR20-10.

Entry informationi

Entry nameiG8T9S6_NIAKG
AccessioniPrimary (citable) accession number: G8T9S6
Entry historyi
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: June 11, 2014
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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