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G8T0P8

- G8T0P8_BRUAO

UniProt

G8T0P8 - G8T0P8_BRUAO

Protein

Elongation factor Tu

Gene

tuf

Organism
Brucella abortus A13334
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 24 (01 Oct 2014)
      Sequence version 1 (22 Feb 2012)
      Previous versions | rss
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    Functioni

    This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi19 – 268GTPUniRule annotation
    Nucleotide bindingi76 – 805GTPUniRule annotation
    Nucleotide bindingi131 – 1344GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-HAMAP
    3. translation elongation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Elongation factorUniRule annotationImported

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciBABO1104320:GKD4-1254-MONOMER.
    BABO1104320:GKD4-1270-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tufUniRule annotation
    ORF Names:BAA13334_I01981Imported, BAA13334_I02004Imported
    OrganismiBrucella abortus A13334Imported
    Taxonomic identifieri1104320 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000006807: Chromosome 1

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Structurei

    3D structure databases

    SMRiG8T0P8. Positions 2-390.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.UniRule annotation
    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

    Phylogenomic databases

    KOiK02358.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. EFACTOR_GTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G8T0P8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAKSKFERTK PHVNIGTIGH VDHGKTSLTA AITKFFGEFK AYDQIDAAPE    50
    ERARGITIST AHVEYETANR HYAHVDCPGH ADYVKNMITG AAQMDGAILV 100
    VSAADGPMPQ TREHILLARQ VGVPAIVVFL NKCDQVDDAE LLELVELEVR 150
    ELLSKYEFPG DEIPIIKGSA LAALEDSSKE LGEDAIRNLM DAVDSYIPTP 200
    ERPIDQPFLM PIEDVFSISG RGTVVTGRVE RGIVKVGEEV EIVGIKATTK 250
    TTVTGVEMFR KLLDQGQAGD NIGALIRGVG REDVERGQVL CKPGSVKPHT 300
    KFKAEAYILT KDEGGRHTPF FTNYRPQFYF RTTDVTGVVT LPAGTEMVMP 350
    GDNVAMDVTL IVPIAMEEKL RFAIREGGRT VGAGIVSSII E 391
    Length:391
    Mass (Da):42,605
    Last modified:February 22, 2012 - v1
    Checksum:iED4CDF37183A900E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003176 Genomic DNA. Translation: AEW17595.1.
    CP003176 Genomic DNA. Translation: AEW17611.1.
    RefSeqiYP_005151598.1. NC_016795.1.
    YP_005151613.1. NC_016795.1.

    Genome annotation databases

    EnsemblBacteriaiAEW17595; AEW17595; BAA13334_I01981.
    AEW17611; AEW17611; BAA13334_I02004.
    GeneIDi11725367.
    11725383.
    KEGGibaa:BAA13334_I01981.
    baa:BAA13334_I02004.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003176 Genomic DNA. Translation: AEW17595.1 .
    CP003176 Genomic DNA. Translation: AEW17611.1 .
    RefSeqi YP_005151598.1. NC_016795.1.
    YP_005151613.1. NC_016795.1.

    3D structure databases

    SMRi G8T0P8. Positions 2-390.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEW17595 ; AEW17595 ; BAA13334_I01981 .
    AEW17611 ; AEW17611 ; BAA13334_I02004 .
    GeneIDi 11725367.
    11725383.
    KEGGi baa:BAA13334_I01981.
    baa:BAA13334_I02004.

    Phylogenomic databases

    KOi K02358.

    Enzyme and pathway databases

    BioCyci BABO1104320:GKD4-1254-MONOMER.
    BABO1104320:GKD4-1270-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. EFACTOR_GTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete Genome Sequence of Brucella abortus A13334, a New Strain Isolated from the Fetal Gastric Fluid of Dairy Cattle."
      Kim H., Jeong W., Jeoung H.Y., Song J.Y., Kim J.S., Beak J.H., Parisutham V., Lee S.K., Kim J.W., Kim J.Y., Jung S.C., Her M., An D.J.
      J. Bacteriol. 194:5444-5444(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: A13334Imported.

    Entry informationi

    Entry nameiG8T0P8_BRUAO
    AccessioniPrimary (citable) accession number: G8T0P8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 22, 2012
    Last sequence update: February 22, 2012
    Last modified: October 1, 2014
    This is version 24 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3