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Protein

Glutamate decarboxylase

Gene

BCA52141_II0717

Organism
Brucella canis HSK A52141
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciBCAN1104321:GJV1-2639-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
ORF Names:BCA52141_II0717Imported
OrganismiBrucella canis HSK A52141Imported
Taxonomic identifieri1104321 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000006808: Chromosome 2

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

KOiK01580.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR021115. Pyridoxal-P_BS.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
PROSITEiPS00392. DDC_GAD_HDC_YDC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G8STU8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTGSNYPARD LIASVFGTEA LQEIAASRGF REKEMQANAV YQIIHDELFL
60 70 80 90 100
DGNARQNLAT FCQTWDDDYV HKLMDLSINK NWIDKEEYPQ SAAIDLRCVN
110 120 130 140 150
MVADLWNAPK FADNATGTNT IGSSEACMLG GMAMKWRWRK KMQEMGKPTD
160 170 180 190 200
KPNFVCGPVQ VCWHKFARYW DVEIREIPME PGRLFMGPEQ MLEAVDENTI
210 220 230 240 250
GVVPTFGVTY TGNYEFPEPL QDALDKLQKT KGLDIDIHVD AASGGFLAPF
260 270 280 290 300
CAPDIPWDFR LPRVKSISAS GHKYGLAPLG CGWVVWRDKE ALPEELIFNV
310
DYLGGQVGTF AINFSRPAG
Length:319
Mass (Da):35,790
Last modified:February 22, 2012 - v1
Checksum:i1903A01A894FDC5C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003175 Genomic DNA. Translation: AEW15625.1.
RefSeqiWP_004690094.1. NC_016796.1.
YP_005153018.1. NC_016796.1.

Genome annotation databases

EnsemblBacteriaiAEW15625; AEW15625; BCA52141_II0717.
GeneIDi11726613.
KEGGibsk:BCA52141_II0717.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003175 Genomic DNA. Translation: AEW15625.1.
RefSeqiWP_004690094.1. NC_016796.1.
YP_005153018.1. NC_016796.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEW15625; AEW15625; BCA52141_II0717.
GeneIDi11726613.
KEGGibsk:BCA52141_II0717.

Phylogenomic databases

KOiK01580.

Enzyme and pathway databases

BioCyciBCAN1104321:GJV1-2639-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR021115. Pyridoxal-P_BS.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
PROSITEiPS00392. DDC_GAD_HDC_YDC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete Genome Sequence of Brucella canis Strain HSK A52141, Isolated from the Blood of an Infected Dog."
    Kim J.S., Jeong W., Jeoung H.Y., Song J.Y., Kim H., Beak J.H., Parisutham V., Lee S.K., Kim J.W., Kim J.Y., Jung S.C., Her M., An D.J.
    J. Bacteriol. 194:5134-5134(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: A52141Imported.

Entry informationi

Entry nameiG8STU8_BRUCA
AccessioniPrimary (citable) accession number: G8STU8
Entry historyi
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: February 4, 2015
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.