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G8SIM4

- G8SIM4_ACTS5

UniProt

G8SIM4 - G8SIM4_ACTS5

Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 14 (01 Oct 2014)
      Sequence version 1 (22 Feb 2012)
      Previous versions | rss
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    Functioni

    Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

    Catalytic activityi

    Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

    Cofactori

    Magnesium.UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei141 – 1411UniRule annotation
    Active sitei578 – 5781UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. carbon fixation Source: UniProtKB-HAMAP
    2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
    3. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotationSAAS annotationImported

    Keywords - Biological processi

    Carbon dioxide fixationUniRule annotationSAAS annotation

    Keywords - Ligandi

    MagnesiumUniRule annotationSAAS annotation, PyruvateImported

    Enzyme and pathway databases

    BioCyciASP134676:GL7H-831-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
    Short name:
    PEPCUniRule annotation
    Short name:
    PEPCaseUniRule annotation
    Gene namesi
    Name:ppcUniRule annotationImported
    Ordered Locus Names:ACPL_925Imported
    OrganismiActinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110)Imported
    Taxonomic identifieri134676 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicromonosporineaeMicromonosporaceaeActinoplanes
    ProteomesiUP000005440: Chromosome

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PEPCase type 1 family.UniRule annotation

    Phylogenomic databases

    KOiK01595.
    OMAiELSTISC.

    Family and domain databases

    HAMAPiMF_00595. PEPcase_type1.
    InterProiIPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view]
    PfamiPF00311. PEPcase. 1 hit.
    [Graphical view]
    PRINTSiPR00150. PEPCARBXLASE.
    SUPFAMiSSF51621. SSF51621. 1 hit.
    PROSITEiPS00781. PEPCASE_1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G8SIM4-1 [UniParc]FASTAAdd to Basket

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    MTELPAHLDE REGPDAELRA DIRRIGTLLG QTLARQEGRP LLDLVEEIRA    50
    LVRQDVPAAA ERLAAMDITT GTKLARAFST YFHLANITEQ VHRARDLRRR 100
    RAKDGGWLDQ AAKRIAERGV PADEIASAAR RLAVRPVFTA HPTEASRRSI 150
    LSKLRQVADS LDAESAAAAL YGDTDTTQST KRFAELIDLL WQTDELRLDR 200
    PDPTDEARNA VYYLKDLYAE AAPQVLDDLA ETLRRLGVET APTSRPLTFG 250
    SWIGGDRDGN PFVTPAVTAA VLLIQHEHGI QATEKVMDKL IEELSVSRRL 300
    RGVSLDLSAS LAQDLDNLPE VADRFRRVNA EEPYRLKVRA IKAKLANTRS 350
    RLQHGTPHVA GRDYLGSDEL IADLELMRAS LARNSGQLPA VGVVATAIRQ 400
    ASAFGLQLAT LDVREHAEKH HEVLQQMYTQ VGEVEDYAAL DRTERTKLLA 450
    AELTGRRPLS SADTPLTDSA RKTFDVFNTI RESQERFGAD VIETYIISMT 500
    LGVDDVLAAA VLAREAGLVD IHTGRARVNI VPLLETPAEL DAGGDLLDEM 550
    LSLPAYRAIV RARGDVQEVM LGYSDSNKEA GITTSQWRIH KAQRSLRDVA 600
    ARHGVRLRLF HGRGGTVGRG GGPTHEAILA QPYGTLDGAI KVTEQGEVIS 650
    DKYTVPALAR ENLELTTAAV LQATLLHTTL SVDPVRLEVW DATMDTTSEA 700
    AFAAYRRLVE NPDLPAYFWA ATPTELLGAL NIGSRPAKRP NADAGLGGLR 750
    AIPWVFGWTQ TRQIVPGWFG VGTGLAAARK AGLGDVLTEM HDNWQFFRTF 800
    LSNVAMMLAK TDLSIARRYV ETLVPEELHP IFATIEAEYD RTVQEVLAIT 850
    GEPRILAAQP ELSRTLGVRD TYLEPLHHLQ VALLRQYRDL SDAARQMPTA 900
    PGARRGPSDS TALERALLTT VNGIAAGMRN TG 932
    Length:932
    Mass (Da):102,288
    Last modified:February 22, 2012 - v1
    Checksum:i503AFB82C588F320
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003170 Genomic DNA. Translation: AEV81822.1.
    RefSeqiWP_014687895.1. NC_017803.1.
    YP_006263890.1. NC_017803.1.

    Genome annotation databases

    EnsemblBacteriaiAEV81822; AEV81822; ACPL_925.
    GeneIDi12821740.
    KEGGiase:ACPL_925.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003170 Genomic DNA. Translation: AEV81822.1 .
    RefSeqi WP_014687895.1. NC_017803.1.
    YP_006263890.1. NC_017803.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEV81822 ; AEV81822 ; ACPL_925 .
    GeneIDi 12821740.
    KEGGi ase:ACPL_925.

    Phylogenomic databases

    KOi K01595.
    OMAi ELSTISC.

    Enzyme and pathway databases

    BioCyci ASP134676:GL7H-831-MONOMER.

    Family and domain databases

    HAMAPi MF_00595. PEPcase_type1.
    InterProi IPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view ]
    Pfami PF00311. PEPcase. 1 hit.
    [Graphical view ]
    PRINTSi PR00150. PEPCARBXLASE.
    SUPFAMi SSF51621. SSF51621. 1 hit.
    PROSITEi PS00781. PEPCASE_1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The complete genome sequence of the acarbose producer Actinoplanes sp. SE50/110."
      Schwientek P., Szczepanowski R., Kalinowski J., Klein A., Selber K., Wehmeier U.F., Stoye J., Puehler A.
      Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 31044 / CBS 674.73 / SE50/110Imported.

    Entry informationi

    Entry nameiG8SIM4_ACTS5
    AccessioniPrimary (citable) accession number: G8SIM4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 22, 2012
    Last sequence update: February 22, 2012
    Last modified: October 1, 2014
    This is version 14 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3