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G8SIM4

- G8SIM4_ACTS5

UniProt

G8SIM4 - G8SIM4_ACTS5

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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Magnesium.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei141 – 1411UniRule annotation
Active sitei578 – 5781UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciASP134676:GL7H-831-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:ACPL_925Imported
OrganismiActinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110)Imported
Taxonomic identifieri134676 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicromonosporineaeMicromonosporaceaeActinoplanes
ProteomesiUP000005440: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.
OMAiELSTISC.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G8SIM4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTELPAHLDE REGPDAELRA DIRRIGTLLG QTLARQEGRP LLDLVEEIRA
60 70 80 90 100
LVRQDVPAAA ERLAAMDITT GTKLARAFST YFHLANITEQ VHRARDLRRR
110 120 130 140 150
RAKDGGWLDQ AAKRIAERGV PADEIASAAR RLAVRPVFTA HPTEASRRSI
160 170 180 190 200
LSKLRQVADS LDAESAAAAL YGDTDTTQST KRFAELIDLL WQTDELRLDR
210 220 230 240 250
PDPTDEARNA VYYLKDLYAE AAPQVLDDLA ETLRRLGVET APTSRPLTFG
260 270 280 290 300
SWIGGDRDGN PFVTPAVTAA VLLIQHEHGI QATEKVMDKL IEELSVSRRL
310 320 330 340 350
RGVSLDLSAS LAQDLDNLPE VADRFRRVNA EEPYRLKVRA IKAKLANTRS
360 370 380 390 400
RLQHGTPHVA GRDYLGSDEL IADLELMRAS LARNSGQLPA VGVVATAIRQ
410 420 430 440 450
ASAFGLQLAT LDVREHAEKH HEVLQQMYTQ VGEVEDYAAL DRTERTKLLA
460 470 480 490 500
AELTGRRPLS SADTPLTDSA RKTFDVFNTI RESQERFGAD VIETYIISMT
510 520 530 540 550
LGVDDVLAAA VLAREAGLVD IHTGRARVNI VPLLETPAEL DAGGDLLDEM
560 570 580 590 600
LSLPAYRAIV RARGDVQEVM LGYSDSNKEA GITTSQWRIH KAQRSLRDVA
610 620 630 640 650
ARHGVRLRLF HGRGGTVGRG GGPTHEAILA QPYGTLDGAI KVTEQGEVIS
660 670 680 690 700
DKYTVPALAR ENLELTTAAV LQATLLHTTL SVDPVRLEVW DATMDTTSEA
710 720 730 740 750
AFAAYRRLVE NPDLPAYFWA ATPTELLGAL NIGSRPAKRP NADAGLGGLR
760 770 780 790 800
AIPWVFGWTQ TRQIVPGWFG VGTGLAAARK AGLGDVLTEM HDNWQFFRTF
810 820 830 840 850
LSNVAMMLAK TDLSIARRYV ETLVPEELHP IFATIEAEYD RTVQEVLAIT
860 870 880 890 900
GEPRILAAQP ELSRTLGVRD TYLEPLHHLQ VALLRQYRDL SDAARQMPTA
910 920 930
PGARRGPSDS TALERALLTT VNGIAAGMRN TG
Length:932
Mass (Da):102,288
Last modified:February 22, 2012 - v1
Checksum:i503AFB82C588F320
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003170 Genomic DNA. Translation: AEV81822.1.
RefSeqiWP_014687895.1. NC_017803.1.
YP_006263890.1. NC_017803.1.

Genome annotation databases

EnsemblBacteriaiAEV81822; AEV81822; ACPL_925.
GeneIDi12821740.
KEGGiase:ACPL_925.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003170 Genomic DNA. Translation: AEV81822.1 .
RefSeqi WP_014687895.1. NC_017803.1.
YP_006263890.1. NC_017803.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEV81822 ; AEV81822 ; ACPL_925 .
GeneIDi 12821740.
KEGGi ase:ACPL_925.

Phylogenomic databases

KOi K01595.
OMAi ELSTISC.

Enzyme and pathway databases

BioCyci ASP134676:GL7H-831-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The complete genome sequence of the acarbose producer Actinoplanes sp. SE50/110."
    Schwientek P., Szczepanowski R., Kalinowski J., Klein A., Selber K., Wehmeier U.F., Stoye J., Puehler A.
    Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 31044 / CBS 674.73 / SE50/110Imported.

Entry informationi

Entry nameiG8SIM4_ACTS5
AccessioniPrimary (citable) accession number: G8SIM4
Entry historyi
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: October 29, 2014
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3