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G8S715

- G8S715_ACTS5

UniProt

G8S715 - G8S715_ACTS5

Protein

Glutamate decarboxylase

Gene

gadB

Organism
Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 14 (01 Oct 2014)
      Sequence version 1 (22 Feb 2012)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotation

    GO - Molecular functioni

    1. glutamate decarboxylase activity Source: UniProtKB-EC
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. glutamate metabolic process Source: InterPro

    Keywords - Molecular functioni

    DecarboxylaseUniRule annotation, Lyase

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Enzyme and pathway databases

    BioCyciASP134676:GL7H-4075-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
    Gene namesi
    Name:gadBImported
    Ordered Locus Names:ACPL_4149Imported
    OrganismiActinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110)Imported
    Taxonomic identifieri134676 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicromonosporineaeMicromonosporaceaeActinoplanes
    ProteomesiUP000005440: Chromosome

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the group II decarboxylase family.UniRule annotation

    Phylogenomic databases

    KOiK01580.
    OMAiKIHERTR.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProiIPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    [Graphical view]
    PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
    PfamiPF00282. Pyridoxal_deC. 1 hit.
    [Graphical view]
    SUPFAMiSSF53383. SSF53383. 1 hit.
    TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    G8S715-1 [UniParc]FASTAAdd to Basket

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    MSTDADAALF GNRFVTQEVP SRTFPDEGMT ATDAFRLVAE EMALEGDPAR    50
    NLATFVTTWM EPEAQRLIAA NLHRNFIDHA EYPLTAEIEQ RCIRMIADLF 100
    HAPGETTGAR TQGSSEAIML AGLSLKWNWR KRRGDTGSPN LVFGGDVHVV 150
    WEKFCRYFDV EPRIVPLRPG RYTIGPEDVE PHLDENTIGV AAVLGTTFTG 200
    HKDDIAGLNH LLLRIRGERG LDVPLHVDAA SGGFVWPFLY PDSPWDFRLE 250
    QVRSINVSGH KFGLVYPGIG WLIFRERADL AEDLVFEENY LGKTDKTFTL 300
    NFSTGSAMVL AQYYNLVRYG RAGYRYIMAN MRANARTLGE KLAAMNRFEL 350
    IGADQEQLPL VAFRLAADNG YDEFDLAWQL SAERGWMVPA YTLPPNAQHV 400
    TIMRALVKET MTRQHVDLLA EDIDDACATL DNKGGAHESE RRRIITGPGH 450
    Length:450
    Mass (Da):50,461
    Last modified:February 22, 2012 - v1
    Checksum:iCC8EA8456B993527
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003170 Genomic DNA. Translation: AEV85044.1.
    RefSeqiWP_014691116.1. NC_017803.1.
    YP_006267112.1. NC_017803.1.

    Genome annotation databases

    EnsemblBacteriaiAEV85044; AEV85044; ACPL_4149.
    GeneIDi12819432.
    KEGGiase:ACPL_4149.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003170 Genomic DNA. Translation: AEV85044.1 .
    RefSeqi WP_014691116.1. NC_017803.1.
    YP_006267112.1. NC_017803.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEV85044 ; AEV85044 ; ACPL_4149 .
    GeneIDi 12819432.
    KEGGi ase:ACPL_4149.

    Phylogenomic databases

    KOi K01580.
    OMAi KIHERTR.

    Enzyme and pathway databases

    BioCyci ASP134676:GL7H-4075-MONOMER.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProi IPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    [Graphical view ]
    PANTHERi PTHR11999:SF1. PTHR11999:SF1. 1 hit.
    Pfami PF00282. Pyridoxal_deC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53383. SSF53383. 1 hit.
    TIGRFAMsi TIGR01788. Glu-decarb-GAD. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The complete genome sequence of the acarbose producer Actinoplanes sp. SE50/110."
      Schwientek P., Szczepanowski R., Kalinowski J., Klein A., Selber K., Wehmeier U.F., Stoye J., Puehler A.
      Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 31044 / CBS 674.73 / SE50/110Imported.

    Entry informationi

    Entry nameiG8S715_ACTS5
    AccessioniPrimary (citable) accession number: G8S715
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 22, 2012
    Last sequence update: February 22, 2012
    Last modified: October 1, 2014
    This is version 14 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3