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Protein

DNA ligase

Gene

ligB

Organism
Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciASP134676:GL7H-1211-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Name:ligBImported
Ordered Locus Names:ACPL_1298Imported
OrganismiActinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110)Imported
Taxonomic identifieri134676 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicromonosporalesMicromonosporaceaeActinoplanes
ProteomesiUP000005440 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi134676.ACPL_1298.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

KOiK10747.
OMAiGRPRPFQ.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 2 hits.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G8S1T4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGIVRFLDIA ATSAAVAATG GRKAKIELLA HALRRLEPDE IAAGSAYLAG
60 70 80 90 100
ELRQRQTGVG YAGLRERPAP ALEPTLTVAG VDASIAEIAT VAGAGSQARR
110 120 130 140 150
RQLLGALFGA ATADEQRLLT GLFSGELRQG AQAGLLTEAI AVAAAVPVTG
160 170 180 190 200
VRRALLLSGD LKQVAAAALT GGAAALAAIS LRVGTPLTPM LAQSAPDIAA
210 220 230 240 250
ALLATGTPAV VDTKLDGIRI QVHRSGDEVA VFTRSLDDIT ERLPGVVAAA
260 270 280 290 300
RALPLREVVL DGEAMALDEQ GRPRPFQETS SRAATRAKTG GTDAAAVLVP
310 320 330 340 350
YFFDLLHLDG TDLLDEPGRV RWAALADALP AGLIVGRQTV ETQEQGAAAF
360 370 380 390 400
AAALAAGQEG VVVKAPDAPY DVGRRGSAWV KVKPRHTLDL VVLAVEWGHG
410 420 430 440 450
RRRGWLSNLH LGARDPETGG FVMLGKTFKG LTDELLRWQT ERFKELAVDD
460 470 480 490 500
NGWVVRVRPE QVVEIAFDGV QTSPRYPGGV ALRFARVLRY RDDKPAAEAD
510
TIDAVRAIGG GAVTS
Length:515
Mass (Da):53,884
Last modified:February 22, 2012 - v1
Checksum:iF2F2CBA77E39B03E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003170 Genomic DNA. Translation: AEV82195.1.

Genome annotation databases

EnsemblBacteriaiAEV82195; AEV82195; ACPL_1298.
KEGGiase:ACPL_1298.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003170 Genomic DNA. Translation: AEV82195.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi134676.ACPL_1298.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEV82195; AEV82195; ACPL_1298.
KEGGiase:ACPL_1298.

Phylogenomic databases

KOiK10747.
OMAiGRPRPFQ.

Enzyme and pathway databases

BioCyciASP134676:GL7H-1211-MONOMER.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 2 hits.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The complete genome sequence of the acarbose producer Actinoplanes sp. SE50/110."
    Schwientek P., Szczepanowski R., Kalinowski J., Klein A., Selber K., Wehmeier U.F., Stoye J., Puehler A.
    Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 31044 / CBS 674.73 / SE50/110Imported.

Entry informationi

Entry nameiG8S1T4_ACTS5
AccessioniPrimary (citable) accession number: G8S1T4
Entry historyi
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: July 22, 2015
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.